Interviewer effects in a cohort study. Results from the Massachusetts Women's Health Study

UMMS Affiliation

New England Research Institutes

Publication Date


Document Type



Depression; *Effect Modifiers (Epidemiology); Female; Humans; Logistic Models; Massachusetts; *Menopause; Middle Aged; Odds Ratio; Predictive Value of Tests; Prospective Studies; Telephone; *Women's Health


Life Sciences | Medicine and Health Sciences | Women's Studies


Although interviewer error is widely recognized as an important source of variation in epidemiologic investigations, scant published information exists documenting the impact of interviewer variation on study findings. Using data from the Massachusetts Women's Health Study, a population-based cohort study of 2,569 middle-aged women (1982-1987), the authors evaluated interviewer variation in responses to different types of questions, and assessed the impact of interviewer variation on inferences derived from study data. Respondent sociodemographic and lifestyle characteristics were similar for the four study interviewers at the first follow-up. No interviewer variation was detected for questions concerning recall of specific events, but responses to questions regarding recall of subjective or personal information or those which required further probing did differ significantly by interviewer. Adjustment for interviewer effects had no impact on the conclusions obtained from one analysis of predictors of depression, despite significant interviewer variation in the outcome and predictor variables, but it did change conclusions from an analysis of the impact of support networks on psychological symptoms, wherein the interviewer variable was strongly related to the outcome after data were controlled for predictor variables. Given these findings, examination of data for interviewer effects is advisable despite incorporation of quality control measures in a study's design.

DOI of Published Version



Am J Epidemiol. 1997 Sep 1;146(5):429-38.

Journal/Book/Conference Title

American journal of epidemiology

Related Resources

Link to article in PubMed

PubMed ID