Title

Drug toxicity, HIV progression, or comorbidity of aging: does tipranavir use increase the risk of intracranial hemorrhage

UMMS Affiliation

Department of Quantitative Health Sciences

Publication Date

2008-11

Document Type

Article

Subjects

Adult; Age Factors; Anti-HIV Agents; California; Cohort Studies; Databases, Factual; Female; HIV Infections; Humans; Intracranial Hemorrhages; Male; Medicaid; Middle Aged; Pyridines; Pyrones; Risk Factors; United States; Veterans

Disciplines

Immune System Diseases | Investigative Techniques | Medical Pharmacology

Abstract

The US Food and Drug Administration has issued a warning that tipranavir may be associated with increased risk of intracranial hemorrhage. We studied 2 large cohorts to estimate the background rate of intracranial hemorrhage and compared it with rates reported among persons who had been exposed to tipranavir.

DOI of Published Version

10.1086/592302

Source

Clin Infect Dis. 2008 Nov 1;47(9):1226-30. doi: 10.1086/592302. Link to article on publisher's site

Journal/Book/Conference Title

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Comments

At the time of publication, Kristin Mattocks was not yet affiliated with the University of Massachusetts Medical School.

Related Resources

Link to Article in PubMed

PubMed ID

18831696

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