Are depressive symptoms associated with cancer screening and cancer stage at diagnosis among postmenopausal women? The Women's Health Initiative observational cohort
Authors
Aggarwal, ArpitaFreund, Karen
Sato, Alicia
Adams-Campbell, Lucile L.
Lopez, Ana Maria
Lessin, Lawrence S.
Ockene, Judith K.
Wallace, Robert B.
Williams, Carla D.
Bonds, Denise E.
UMass Chan Affiliations
Department of Medicine, Division of Preventive and Behavioral MedicineDocument Type
Journal ArticlePublication Date
2008-10-01Keywords
AgedBreast Neoplasms
Cohort Studies
Colorectal Neoplasms
Depressive Disorder
Endoscopy
Feces
Female
Humans
Linear Models
Mammography
Mass Screening
Middle Aged
Neoplasm Staging
Patient Acceptance of Health Care
Postmenopause
Psychiatric Status Rating Scales
Risk Factors
United States
Women's Health
Life Sciences
Medicine and Health Sciences
Women's Studies
Metadata
Show full item recordAbstract
BACKGROUND: Women with depressive symptoms may use preventive services less frequently and experience poorer health outcomes. We investigated the association of depressive symptoms with breast and colorectal cancer screening rates and stage of cancer among a cohort of postmenopausal women. METHODS: In The Women's Health Initiative Observational Study, 93,676 women were followed on average for 7.6 years. Depressive symptoms were measured at baseline and at 3 years using the 6-item scale from the Center for Epidemiological Studies Depression scale (CES-D). We calculated a cancer screening rate expressed as a proportion of the years that women were current with recommended cancer screening over the number of follow-up visits in the study. Breast and colorectal cancers were staged based on Surveillance, Epidemiology and End Results (SEER) classification. RESULTS: At baseline, 15.8% (12,621) women were positive for depressive symptoms, and 6.9% (4,777) were positive at both baseline screening and at 3 years. The overall average screening rate was 71% for breast cancer and 53% for colorectal cancer. The breast cancer screening rate was 1.5% (CI 0.9%-2.0%) lower among women who reported depressive symptoms at baseline than among those who did not. Depressive symptoms were not a predictor for colorectal cancer screening. Stage of breast and colorectal cancer was not found to be associated with depressive symptoms after adjusting for covariates. CONCLUSIONS: Among a healthy and self-motivated cohort of women, self-reported depressive symptoms were associated with lower rates of screening mammography but not with colorectal cancer screening.Source
J Womens Health (Larchmt). 2008 Oct;17(8):1353-61. Link to article on publisher's site
DOI
10.1089/jwh.2007.0544Permanent Link to this Item
http://hdl.handle.net/20.500.14038/50962PubMed ID
18788983Related Resources
ae974a485f413a2113503eed53cd6c53
10.1089/jwh.2007.0544