Practical behavioral trials to advance evidence-based behavioral medicine

UMMS Affiliation

Department of Medicine, Division of Preventive and Behavioral Medicine

Publication Date


Document Type



Behavioral Medicine; *Clinical Trials as Topic; Diabetes Mellitus; Evidence-Based Medicine; Humans; Interdisciplinary Communication; Patient Care Team; Therapy, Computer-Assisted


Life Sciences | Medicine and Health Sciences | Women's Studies


There is a well-documented gap between research and practice in many areas of behavioral medicine. This gap is due in part to limitations in the capacity of the research database to address questions that are of central concern to clinicians, administrative decision makers, and policymakers. Thus, there has been a call for "practical clinical trials" that compare clinically viable alternative interventions and assess multiple outcomes important for clinical and policy decisions in diverse patient populations and settings. Such trials offer great potential, and they raise interesting challenges regarding optimal research design and source of funding. We discuss issues related to practical clinical trials in behavioral medicine, propose a need for practical behavioral trials (PBTs), and describe design features that will facilitate clinical and policy decision making. This type of PBT can help to close the gap between research and practice and advance the field of evidence-based behavioral medicine. We discuss potential challenges and objections to PBTs and conclude by providing recommendations for the design, conduct, reporting, and review of practical trials.

DOI of Published Version



Ann Behav Med. 2006 Feb;31(1):5-13. Link to article on publisher's site

Journal/Book/Conference Title

Annals of behavioral medicine : a publication of the Society of Behavioral Medicine

Related Resources

Link to article in PubMed

PubMed ID