The University of Massachusetts Center for Clinical and Translational Science (UMCCTS) was founded in 2006 to enhance clinical and translational research across the five University of Massachusetts campuses (Amherst, Boston, Dartmouth, Lowell, UMass Medical School) and our clinical partners, UMass Memorial Health Care and Baystate Medical Center. With the receipt of an NIH Clinical and Translational Science Award (CTSA) in 2010, and its successful renewal in 2015, the UMCCTS joined a network of 62 NIH-funded centers collaborating to transform the conduct of clinical and translational research across the U.S. Other key partners include our patients and communities, foundations, biotechnology and pharmaceutical companies, and members of the venture capital and philanthropic communities. Our goals are to accelerate basic discoveries and develop and support the next generation in clinical and translational research. This collection showcases publications that are the result of UMCCTS supported research.

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Publications from 2011

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30-year trends in heart failure in patients hospitalized with acute myocardial infarction, David D. McManus, Marcello Chinali, Jane S. Saczynski, Joel M. Gore, Jorge L. Yarzebski, Frederick A. Spencer, Darleen M. Lessard, and Robert J. Goldberg

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Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI, David D. McManus, Joel M. Gore, Jorge L. Yarzebski, Frederick A. Spencer, Darleen M. Lessard, and Robert J. Goldberg

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Adipose tissue palmitoleic acid and obesity in humans: does it behave as a lipokine, Jian Gong, Hannia Campos, Stephen McGarvey, Zhijin Wu, Robert J. Goldberg, and Ana Baylin

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Geographic and demographic variability in 20-year hypertension incidence: the CARDIA study, Deborah A. Levine, Cora E. Lewis, O. Dale Williams, Monika M. Safford, Kiang Liu, David A. Calhoun, Yongin Kim, David R. Jacobs Jr., and Catarina I. Kiefe

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Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity, Olga T. Hardy, Richard A. Perugini, Sarah M. Nicoloro, Karen A. Gallagher-Dorval, Vishwajeet Puri, Juerg R. Straubhaar, and Michael P. Czech

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A new look at quantifying tobacco exposure during pregnancy using fuzzy clustering, Hua Fang, Craig Johnson, Christian Stopp, and Kimberly Andrews Espy

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Physician and Patient Influences on Provider Performance: {beta}-Blockers in Post-Myocardial Infarction Management in the MI-Plus Study, Ellen M. Funkhouser, Thomas K. Houston, Deborah A. Levine, Joshua S. Richman, Jeroan J. Allison, and Catarina I. Kiefe

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Racial/ethnic disparities in access to physician care and medications among US stroke survivors, Deborah A. Levine, M. V. Neidecker, Catarina I. Kiefe, S. Karve, L. S. Williams, and Jeroan J. Allison

Publications from 2008

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Gene therapy for cystic fibrosis, Christian Mueller and Terence R. Flotte