The University of Massachusetts Center for Clinical and Translational Science (UMCCTS) was founded in 2006 to enhance clinical and translational research across the five University of Massachusetts campuses (Amherst, Boston, Dartmouth, Lowell, UMass Medical School) and our clinical partners, UMass Memorial Health Care and Baystate Medical Center. With the receipt of an NIH Clinical and Translational Science Award (CTSA) in 2010, and its successful renewal in 2015, the UMCCTS joined a network of 62 NIH-funded centers collaborating to transform the conduct of clinical and translational research across the U.S. Other key partners include our patients and communities, foundations, biotechnology and pharmaceutical companies, and members of the venture capital and philanthropic communities. Our goals are to accelerate basic discoveries and develop and support the next generation in clinical and translational research. This collection showcases publications that are the result of UMCCTS supported research.

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Publications from 2013

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Delayed hospital presentation in acute decompensated heart failure: Clinical and patient reported factors, Chad E. Darling, Jane S. Saczynski, David D. McManus, Darleen M. Lessard, Frederick A. Spencer, and Robert J. Goldberg

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Gestational angiogenic biomarker patterns in high risk preeclampsia groups, Sharon E. Maynard, Sybil L. Crawford, Susanne Bathgate, Jing Yan, Laura Robidoux, Melissa J. Moore, and Tiffany A. Moore Simas

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Ahead of the curve: next generation estimators of drug resistance in malaria infections, Nicole Mideo, David A. Kennedy, Jane M. Carlton, Jeffrey A. Bailey, Jonathan J. Juliano, and Andrew F. Read

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Humoral and Cellular Immunity to Plasmodium falciparum Merozoite Surface Protein 1 and Protection from Blood-stage Infection, Ann M. Moormann, Peter Odada Sumba, Kiprotich Chelimo, Hua Fang, Daniel J. Tisch, Arlene E. Dent, Chandy C. John, Carole A. Long, John Vulule, and James W. Kazura

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Rethinking the composition of a rational antibiotic arsenal for the 21st century, Margaret A. Riley, Sandra M. Robinson, Christopher M. Roy, and Robert L. Dorit

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Community Mental Health Provider Reluctance to Provide Pharmacotherapy May Be a Barrier to Addressing Perinatal Depression: A Preliminary Study, Nancy Byatt, Kathleen Biebel, Gifty Debordes-Jackson, Rebecca S. Lundquist, Tiffany A. Moore Simas, Linda F. Weinreb, and Douglas M. Ziedonis

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GABAergic neuroactive steroids and resting-state functional connectivity in postpartum depression: a preliminary study, Kristina M. Deligiannidis, Elif M. Sikoglu, Scott A. Shaffer, Blaise Frederick, Abby E. Svenson, Andre Kopoyan, Chelsea A. Kosma, Anthony J. Rothschild, and Constance M. Moore

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Contemporary trends in necrotizing soft-tissue infections in the United States, Charles M. Psoinos, Julie M. Flahive, Joshua J. Shaw, YouFu Li, Sing Chau Ng, Jennifer F. Tseng, and Heena P. Santry

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A meta-composite software development approach for translational research, Rajani S. Sadasivam and Murat M. Tanik

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Interference Mitigation for Cyber-Physical Wireless Body Area Network System Using Social Networks, Zhaoyang Zhang, Honggang Wang, Chonggang Wang, and Hua (Julia) Fang

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Improved survival after heart failure: a community-based perspective, Samuel W. Joffe, Kristy T. Webster, David D. McManus, Michael S. Kiernan, Darleen M. Lessard, Jorge L. Yarzebski, Chad E. Darling, Joel M. Gore, and Robert J. Goldberg

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Recent Trends in the Incidence, Treatment, and Prognosis of Patients With Heart Failure and Atrial Fibrillation (the Worcester Heart Failure Study), David D. McManus, Jane S. Saczynski, Darleen M. Lessard, Menhel Kinno, Rahul Pidikiti, Nada Esa, Josephine Harrington, and Robert J. Goldberg

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Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction, Li Zhong, Nirav Malani, Mengxin Li, Troy Brady, Jun Xie, Peter Bell, Shaoyong Li, Haven Jones, James M. Wilson, Terence R. Flotte, Frederic D. Bushman, and Guangping Gao

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Diversity of T cell epitopes in Plasmodium falciparum circumsporozoite protein likely due to protein-protein interactions, Nagesh R. Aragam, Kelly M. Thayer, Nabi Nge, Irving Hoffman, Francis Martinson, Debbie Kamwendo, Feng-Chang Lin, Colin Sutherland, Jeffrey A. Bailey, and Jonathan J. Juliano

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Gene transfer in the liver using recombinant adeno-associated virus, Seemin Seher Ahmed, Jia Li, Jonathan G. Godwin, Guangping Gao, and Li Zhong

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Contemporary Prevalence and Correlates of Incident Heart Failure with Preserved Ejection Fraction, Jerry H. Gurwitz, David J. Magid, David H. Smith, Robert J. Goldberg, David D. McManus, Larry A. Allen, Jane S. Saczynski, Micah L. Thorp, Grace Hsu, Sue Hee Sung, and Alan S. Go

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Who participates in web-assisted tobacco interventions? The quit-primo and national dental practice-based research network hi-quit studies, Rajani S. Sadasivam, Rebecca L. Kinney, Kathryn L. Delaughter, Sowmya R. Rao, Jessica Hillman Williams, Heather L. Coley, Midge N. Ray, Gregg H. Gilbert, Jeroan J. Allison, Daniel E. Ford, and Thomas K. Houston

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Timing of video capsule endoscopy relative to overt obscure GI bleeding: implications from a retrospective study, Anupam Singh, Christopher Marshall, Biswashree Chaudhuri, Chidimma Okoli, Anne Foley, Sharina D. Person, Kanishka Bhattacharya, and David R. Cave

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Timing of video capsule endoscopy relative to overt obscure GI bleeding: implications from a retrospective study, Anupam Singh, Christopher Marshall, Biswashree Chaudhuri, Chidimma Okoli, Anne Foley, Sharina D. Person, Kanishka Bhattacharya, and David R. Cave

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Gene transfer to the CNS using recombinant adeno-associated virus, Lorelei Stoica, Seemin Seher Ahmed, Guangping Gao, and Miguel Sena-Esteves

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Mediation of smoking-associated postoperative mortality by perioperative complications in veterans undergoing elective surgery: data from Veterans Affairs Surgical Quality Improvement Program (VASQIP)--a cohort study, Jasvinder A. Singh, Mary T. Hawn, Elizabeth J. Campagna, William G. Henderson, Joshua S. Richman, and Thomas K. Houston

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Characterization of FUS mutations in amyotrophic lateral sclerosis using RNA-Seq, Marka van Blitterswijk, Eric T. Wang, Brad A. Friedman, Pamela J. Keagle, Ashley Lyn Leclerc, Leonard H. van den Berg, David E. Housman, Jan H. Veldink, John E. Landers, and Patrick Lowe

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Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium, Alvaro Alonso, David D. McManus, and CHARGE‐AF Consortium

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GLI1 regulates a novel neuropilin-2/alpha6beta1 integrin based autocrine pathway that contributes to breast cancer initiation, Hira Lal Goel, Bryan M. Pursell, Cheng Chang, Leslie M. Shaw, Junhao Mao, Karl Simin, Prashant Kumar, Craig W. Vander Kooi, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Charlotte Kuperwasser, and Arthur M. Mercurio

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The Tec kinase ITK regulates thymic expansion, emigration, and maturation of gammadelta NKT cells, Catherine C. Yin, Ok Hyun Cho, Katelyn E. Sylvia, Kavitha Narayan, Amanda L. Prince, John W. Evans, Joonsoo Kang, and Leslie J. Berg

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Internal versus external motivation in referral of primary care patients with depression to an internet support group: randomized controlled trial, Benjamin W. Van Voorhees, Robert C. Hsiung, Monika Marko-Holguin, Thomas K. Houston, Joshua Fogel, Royce Lee, and Daniel E. Ford

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Changes in Waist Circumference and Body Mass Index in the US CARDIA Cohort: Fixed-Effects Associations with Self-Reported Experiences of Racial/Ethnic Discrimination, Timothy J. Cunningham, Lisa F. Berkman, Ichiro Kawachi, David R. Jacobs Jr., Teresa E. Seeman, Catarina I. Kiefe, and Steven L. Gortmaker

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A novel application for the detection of an irregular pulse using an iPhone 4S in patients with atrial fibrillation, David D. McManus, Jinseok Lee, Oscar Maitas, Nada Esa, Rahul Pidikiti, Alex Carlucci, Josephine Harrington, Eric Mick, and Ki H. Chon

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Is routine intraoperative cholangiogram necessary in the twenty-first century? A national view, Elizaveta Ragulin Coyne, Elan R. Witkowski, Zeling Chau, Sing Chau Ng, Heena P. Santry, Mark P. Callery, Shimul A. Shah, and Jennifer F. Tseng

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Internet health information seeking is a team sport: analysis of the Pew Internet Survey, Rajani S. Sadasivam, Mark J. Sotir, Rebecca L. Kinney, Stephenie C. Lemon, Stephanie L. Shimada, Jeroan J. Allison, and Thomas K. Houston

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Patient-provider secure messaging in VA: variations in adoption and association with urgent care utilization, Stephanie L. Shimada, Timothy P. Hogan, Sowmya R. Rao, Jeroan J. Allison, Ann L. Quill, Hua Feng, Barrett Phillips, Kim M. Nazi, Susan T. Haidary, and Thomas K. Houston

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Cluster-randomized trial of a web-assisted tobacco quality improvement intervention of subsequent patient tobacco product use: A national dental PBRN study, Thomas K. Houston, Kathryn L. Delaughter, Midge N. Ray, Gregg H. Gilbert, Jeroan J. Allison, Catarina I. Kiefe, and Julie E. Volkman

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Antidepressant use in pregnancy: a critical review focused on risks and controversies, Nancy Byatt, Kristina M. Deligiannidis, and Marlene P. Freeman

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Greater knowledge and appreciation of commonly-used research study designs, Robert J. Goldberg, David D. McManus, and Jeroan J. Allison

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Gene transfer in skeletal and cardiac muscle using recombinant adeno-associated virus, Alisha M. Gruntman, Lawrence T. Bish, Christian Mueller, H. Lee Sweeney, Terence R. Flotte, and Guangping Gao

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Increased Toll-like receptor (TLR) mRNA expression in monocytes is a feature of metabolic syndrome in adolescents, Olga T. Hardy, Albert Kim, Carol A. Ciccarelli, Laura L. Hayman, and Jean Wiecha

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Atrial fibrillation and outcomes in heart failure with preserved versus reduced left ventricular ejection fraction, David D. McManus, Grace Hsu, Sue Hee Sung, Jane S. Saczynski, David H. Smith, David J. Magid, Jerry H. Gurwitz, Robert J. Goldberg, and Alan S. Go

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Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases, Jacques P. Tremblay, Terence R. Flotte, and Guangping Gao

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Retinal gene delivery by rAAV and DNA electroporation, Aditya Venkatesh, Shan Ma, Fernanda Langellotto, Guangping Gao, and Claudio Punzo

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Closing the Feedback Loop: An Interactive Voice Response System to Provide Follow-up and Feedback in Primary Care Settings, James H. Willig, Marc Krawitz, Anantachai Panjamapirom, Midge N. Ray, Christa R. Nevin, Thomas M. English, Mark P. Cohen, and Eta S. Berner

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Evaluation of intravenous voriconazole in patients with compromised renal function, Craig M. Lilly, Verna Welch, Thomas Mayer, Paul Ranauro, Joanne Meisner, and David R. Luke

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Young patients hospitalized with an acute coronary syndrome, Hamza H. Awad, David D. McManus, Frederick A. Anderson Jr., Joel M. Gore, and Robert J. Goldberg

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Racial discrimination, racial/ethnic segregation, and health behaviors in the CARDIA study, Luisa N. Borrell, Catarina I. Kiefe, Ana V. Diez-Roux, David R. Williams, and Penny Gordon-Larsen

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Validation of acute myocardial infarction in the Food and Drug Administration's Mini-Sentinel program, Sarah L. Cutrona, Sengwee Toh, Aarthi Iyer, Sarah Foy, Gregory W. Daniel, Vinit P. Nair, Daniel Ng, Melissa G. Butler, Denise M. Boudreau, Susan Forrow, Robert J. Goldberg, Joel M. Gore, David D. McManus, Judith A. Racoosin, and Jerry H. Gurwitz

Publications from 2012

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Speckle echocardiographic left atrial strain and stiffness index as predictors of maintenance of sinus rhythm after cardioversion for atrial fibrillation: a prospective study, Amir Y. Shaikh, Abhishek Mann, Umar A. Khan, Gerard P. Aurigemma, Jeffrey C. Hill, Jennifer L. Kane, Dennis A. Tighe, Eric Mick, and David D. McManus

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Resistance is futile: the bacteriocin model for addressing the antibiotic resistance challenge, Margaret A. Riley, Sandra M. Robinson, Christopher M. Roy, Morgan Dennis, Vivian Liu, and Robert L. Dorit

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The Ottawa Statement on the Ethical Design and Conduct of Cluster Randomized Trials, Charles Weijer, Jeremy M. Grimshaw, Martin P. Eccles, Andrew D. McRae, Angela White, Jamie C. Brehaut, Monica Taljaard, Ottawa Ethics of Cluster Randomized Trials Consensus Group, and Catarina I. Kiefe

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Brief depressive symptoms in patients with bipolar disorder: analysis of long-term self-reported data, Michael Bauer, Tasha Glenn, Michael Keil, Rita Bauer, Wendy K. Marsh, Paul Grof, Martin Alda, Kemal Sagduyu, Greg Murray, Danilo Quiroz, Christopher Baethge, and Peter C. Whybrow

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Atherosclerotic Risk Factors and Their Association With Hospital Mortality Among Patients With First Myocardial Infarction (from the National Registry of Myocardial Infarction), John G. Canto, Catarina I. Kiefe, William J. Rogers, Eric D. Peterson, Paul D. Frederick, William J. French, C. Michael Gibson, Charles V. Pollack Jr., Joseph P. Ornato, Robert J. Zalenski, Jan Penney, Alan J. Tiefenbrunn, Philip Greenland, and NRMI Investigators

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MedTxting: learning based and knowledge rich SMS-style medical text contraction, Feifan LIu, Soheil Moosavinasab, Thomas K. Houston, and Hong Yu

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Trends in atrial fibrillation in patients hospitalized with an acute coronary syndrome, David D. McManus, Wei Huang, Kunal V. Domakonda, Jeanine Ward, Jane S. Saczynski, Joel M. Gore, and Robert J. Goldberg

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Using a resource effect study pre-pilot to inform a large randomized trial: the Decide2Quit.Org Web-assisted tobacco intervention, Rajani S. Sadasivam, Jeroan J. Allison, Midge N. Ray, Daniel E. Ford, and Thomas K. Houston

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The CPEB protein Orb2 has multiple functions during spermatogenesis in Drosophila melanogaster, Shuwa Xu, Nathaniel Hafer, Blessing Agunwamba, and Paul Schedl

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Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2β, Sohan Punia, Kyle K. Rumery, Elizabeth A. Yu, Christopher M. Lambert, Abner L. Notkins, and David R. Weaver

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An update on the prognosis of patients with atrial fibrillation, David D. McManus, Michael Rienstra, and Emelia J. Benjamin

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Detecting Graded Exposure Effects: A Report on an East Boston Pregnancy Cohort, Hua Julia Fang, Vanja Dukic, Kate E. Pickett, Lauren Wakschlag, and Kimberly Andrews Espy

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Transitions, Risks, and Actions in Coronary Events--Center for Outcomes Research and Education (TRACE-CORE): Design and Rationale, Molly E. Waring, Richard H. McManus, Jane S. Saczynski, Milena D. Anatchkova, David D. McManus, Randolph Devereaux, Robert J. Goldberg, Jeroan J. Allison, and Catarina I. Kiefe

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Risk-adjusted payment and performance assessment for primary care, Arlene S. Ash and Randall P. Ellis

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Web-based smoking cessation intervention that transitions from inpatient to outpatient: study protocol for a randomized controlled trial, Kathleen F. Harrington, Julie A. McDougal, Maria Pisu, Bin Zhang, Rajani S. Sadasivam, Thomas K. Houston, and William C. Bailey

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Centre volume and resource consumption in liver transplantation, Christopher W. Macomber, Joshua J. Shaw, Heena P. Santry, Reza F. Saidi, Nicolas Jabbour, Jennifer F. Tseng, Adel Bozorgzadeh, and Shimul A. Shah

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Progression of female reproductive stages associated with bipolar illness exacerbation, Wendy K. Marsh, Terence A. Ketter, Sybil L. Crawford, Julia V. Johnson, Aimee R. Kroll-Desrosiers, and Anthony J. Rothschild

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The dangers of being a "weekend warrior": A new call for injury prevention efforts, Charles M. Psoinos, A. Emhoff Timothy, W. Brian Sweeney, Jennifer F. Tseng, and Heena P. Santry

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Gender Differences in the Fagerström Test for Nicotine Dependence in Korean Americans, Sun Kim, (Julia) Hua Fang, Joseph R. DiFranza, Douglas M. Ziedonis, and Grace X. Ma

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Genome-wide identification and characterization of replication origins by deep sequencing, Jia Xu, Yoshimi Yanagisawa, Alexander M. Tsankov, Christopher Hart, Keita Aoki, Naveen Kommajosyula, Kathleen E. Steinmann, James Bochicchio, Carsten Russ, Aviv Regev, Oliver J. Rando, Chad Nusbaum, Hironori Niki, Patrice Milos, Zhiping Weng, and Nicholas R. Rhind

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HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells, Haojian Zhang, Huawei Li, Hualin S. Xi, and Shaoguang Li

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Long-term, efficient inhibition of microRNA function in mice using rAAV vectors, Jun Xie, Stefan L. Ameres, Randall H. Friedline, Jui-Hung Hung, Yu Zhang, Qing Xie, Li Zhong, Qin Su, Ran He, Mengxin Li, Huapeng Li, Xin Mu, Hongwei Zhang, Jennifer A. Broderick, Jason K. Kim, Zhiping Weng, Terence R. Flotte, Phillip D. Zamore, and Guangping Gao

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Effects of a multicomponent wellness intervention on dyslipidemia among overweight adolescents, Olga T. Hardy, Jean Wiecha, Albert Kim, Carlos Salas, Rayna Briceno, Kwesi Moody, Joan Becker, Greer Glazer, Carol A. Ciccarelli, Ling Shi, and Laura L. Hayman

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The role of unconscious bias in surgical safety and outcomes, Heena P. Santry and Sherry M. Wren

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A systematic review of validated methods for identifying heart failure using administrative data, Jane S. Saczynski, Susan E. Andrade, Leslie R. Harrold, Jennifer Tjia, Sarah L. Cutrona, Katherine S. Dodd, Robert J. Goldberg, and Jerry H. Gurwitz

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A systematic review of validated methods for identifying cerebrovascular accident or transient ischemic attack using administrative data, Susan E. Andrade, Leslie R. Harrold, Jennifer Tjia, Sarah L. Cutrona, Jane S. Saczynski, Katherine S. Dodd, Robert J. Goldberg, and Jerry H. Gurwitz

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Design for validation of acute myocardial infarction cases in Mini-Sentinel, Sarah L. Cutrona, Sengwee Toh, Aarthi Iyer, Sarah Foy, Elizabeth Cavagnaro, Susan Forrow, Judith A. Racoosin, Robert J. Goldberg, and Jerry H. Gurwitz

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Is it worth looking? Abdominal imaging after pancreatic cancer resection: a national study, Elan R. Witkowski, Jillian K. Smith, Elizaveta Ragulin-Coyne, Sing Chau Ng, Shimul A. Shah, and Jennifer F. Tseng

Publications from 2011

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Assessment of differential item functioning in the experiences of discrimination index: the Coronary Artery Risk Development in Young Adults (CARDIA) Study, Timothy J. Cunningham, Lisa F. Berkman, Steven L. Gortmaker, Catarina I. Kiefe, David R. Jacobs Jr., Teresa E. Seeman, and Ichiro Kawachi

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Genetic variation in stearoyl-CoA desaturase 1 is associated with metabolic syndrome prevalence in Costa Rican adults, Jian Gong, Hannia Campos, Stephen T. McGarvey, Zhijin Wu, Robert J. Goldberg, and Ana Baylin

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Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains, Zhao Zhang, Jia Xu, Birgit S. Koppetsch, Jie Wang, Cindy Tipping, Shengmei Ma, Zhiping Weng, William E. Theurkauf, and Phillip D. Zamore

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Venous thromboembolism in patients with reduced estimated GFR: a population-based perspective, Amisha M. Parikh, Frederick A. Spencer, Darleen M. Lessard, Catherine Emery, Ana Baylin, Crystal Linkletter, and Robert J. Goldberg

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Development of an interactive, Web-delivered system to increase provider-patient engagement in smoking cessation, Rajani S. Sadasivam, Kathryn Delaughter, Katie Crenshaw, Heather J. Sobko, Jessica H. Williams, Heather L. Coley, Midge N. Ray, Daniel E. Ford, Jeroan J. Allison, and Thomas K. Houston

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Long-term Trends in Short-term Outcomes in Acute Myocardial Infarction, Hoa L. Nguyen, Jane S. Saczynski, Joel M. Gore, Molly E. Waring, Darleen M. Lessard, Jorge L. Yarzebski, George W. Reed, Frederick A. Spencer, Shu-Xia Li, and Robert J. Goldberg

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The Plasma Membrane-Associated GTPase Rin Interacts with the Dopamine Transporter and Is Required for Protein Kinase C-Regulated Dopamine Transporter Trafficking, Deanna M. Navaroli, Zachary H. Stevens, Zeljko Uzelac, Luke Gabriel, Michael J. King, Lawrence M. Lifshitz, Harald H. Sitte, and Haley E. Melikian

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Recruitment activities for a nationwide, population-based, group-randomized trial: the VA MI-Plus study, Ellen M. Funkhouser, Deborah A. Levine, Joe K. Gerald, Thomas K. Houston, Nancy K. Johnson, Jeroan J. Allison, and Catarina I. Kiefe

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Weight and mortality following heart failure hospitalization among diabetic patients, Molly E. Waring, Jane S. Saczynski, David D. McManus, Michael Zacharias, Darleen M. Lessard, Joel M. Gore, and Robert J. Goldberg

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Thirty-year (1975 to 2005) trends in the incidence rates, clinical features, treatment practices, and short-term outcomes of patients [less than] 55 years of age hospitalized with an initial acute myocardial infarction, David D. McManus, Stephen M. Piacentine, Darleen M. Lessard, Joel M. Gore, Jorge L. Yarzebski, Frederick A. Spencer, and Robert J. Goldberg

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A prospective study of the rate of progression in compensated, histologically advanced chronic hepatitis C, Jules L. Dienstag, Marc G. Ghany, Timothy R. Morgan, Adrian M. Di Bisceglie, Herbert L. Bonkovsky, Hae-Young Kim, Leonard B. Seeff, Gyongyi Szabo, Elizabeth C. Wright, Richard K. Sterling, Gregory T. Everson, Karen L. Lindsay, William M. Lee, Anna S. F. Lok, Chihiro Morishima, Anne M. Stoddard, and James E. Everhart

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Racial variation in willingness to trade financial resources for life-prolonging cancer treatment, Michelle Y. Martin, Maria Pisu, Robert A. Oster, Julie M. Urmie, Deborah Schrag, Haiden A. Huskamp, Jeannette Lee, Catarina I. Kiefe, and Mona N. Fouad

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Six-month mortality and cardiac catheterization in non-ST-segment elevation myocardial infarction patients with anemia, Wen-Chih Wu, Molly E. Waring, Darleen M. Lessard, Jorge L. Yarzebski, Joel M. Gore, and Robert J. Goldberg

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Fast food restaurants and food stores: longitudinal associations with diet in young to middle-aged adults: the CARDIA study, Janne Boone-Heinonen, Penny Gordon-Larsen, Catarina I. Kiefe, James M. Shikany, Cora E. Lewis, and Barry M. Popkin

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Temporal Trends in Presentation for Outpatient HIV Medical Care 2000-2010: Implications for Short-term Mortality, Paula S. Seal, David A. Jackson, Eric Chamot, James H. Willig, Christa R. Nevin, Jeroan J. Allison, James L. Raper, Mirjam Kempf, Joseph E. Schumacher, Michael S. Saag, and Michael J. Mugavero

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Activating peripheral arterial disease patients to reduce cholesterol: a randomized trial, Mary McGrae McDermott, George W. Reed, Philip Greenland, Kathleen M. Mazor, Sherry L. Pagoto, Judith K. Ockene, Rex Graff, Philip A. Merriam, Katherine Leung, Larry Manheim, Melina R. Kibbe, Barbara C. Olendzki, William H. Pearce, and Ira S. Ockene

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Professional values and reported behaviours of doctors in the USA and UK: quantitative survey, Martin Roland, Sowmya R. Rao, Bonnie Sibbald, Mark Hann, Stephen Harrison, Alex Walter, Bruce Guthrie, Catherine M. DesRoches, Timothy G. Ferris, and Eric G. Campbell

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Food insufficiency and health services utilization in a national sample of homeless adults, Travis P. Baggett, Daniel E. Singer, Sowmya R. Rao, James J. O'Connell, Monica Bharel, and Nancy A. Rigotti

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Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants, Nicholas Renzette, Bornali Bhattacharjee, Jeffrey D. Jensen, Laura L. Gibson, and Timothy F. Kowalik

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Social isolation, C-reactive protein, and coronary heart disease mortality among community-dwelling adults, Kathi L. Heffner, Molly E. Waring, Mary B. Roberts, Charles B. Eaton, and Robert Gramling

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Electronic health records in small physician practices: availability, use, and perceived benefits, Sowmya R. Rao, Catherine M. DesRoches, Karen Donelan, Eric G. Campbell, Paola D. Miralles, and Ashish K. Jha

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Randomized trial of a literacy-sensitive, culturally tailored diabetes self-management intervention for low-income latinos: latinos en control, Milagros C. Rosal, Ira S. Ockene, Angela Restrepo, Mary Jo White, Amy Borg, Barbara C. Olendzki, Jeffrey Scavron, Lucy M. Candib, Garry Welch, and George W. Reed

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Neighborhood socioeconomic status predictors of physical activity through young to middle adulthood: the CARDIA study, Janne Boone-Heinonen, Ana V. Diez-Roux, Catarina I. Kiefe, Cora E. Lewis, David K. Guilkey, and Penny Gordon-Larsen

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Socioeconomic status and polycystic ovary syndrome, Sharon Stein Merkin, Ricardo Azziz, Teresa E. Seeman, Ronit Calderon-Margalit, Martha L. Daviglus, Catarina I. Kiefe, Karen A. Matthews, Barbara Sternfeld, and David S. Siscovick

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Patient complexity and diabetes quality of care in rural settings, Amanda H. Salanitro, Monika M. Safford, Thomas K. Houston, Jessica H. Williams, Fernando Ovalle, Pamela Payne-Foster, Jeroan J. Allison, and Carlos A. Estrada

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What Should We Include in a Cultural Competence Curriculum? An Emerging Formative Evaluation Process to Foster Curriculum Development, Katie Crenshaw, Richard M. Shewchuk, Haiyan Qu, Lisa J. Stanton, Judy Ann Bigby, Thomas K. Houston, Jeroan J. Allison, and Carlos A. Estrada

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Cognitive Mapping Tobacco Control Advice for Dentistry: A Dental PBRN Study, Haiyan Qu, Thomas K. Houston, Jessica H. Williams, Gregg H. Gilbert, and Richard M. Shewchuk

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Alcohol Screening and Risk of Postoperative Complications in Male VA Patients Undergoing Major Non-cardiac Surgery, Katharine A. Bradley, Anna D. Rubinsky, Haili Sun, Chris L. Bryson, Michael J. Bishop, David K. Blough, William G. Henderson, Charles Maynard, Mary T. Hawn, Hanne Tonnesen, Grant Hughes, Lauren A. Beste, Alex H.S. Harris, Eric J. Hawkins, Thomas K. Houston, and Daniel R. Kivlahan