The University of Massachusetts Center for Clinical and Translational Science (UMCCTS) was founded in 2006 to enhance clinical and translational research across the five University of Massachusetts campuses (Amherst, Boston, Dartmouth, Lowell, UMass Medical School) and our clinical partners, UMass Memorial Health Care and Baystate Medical Center. With the receipt of an NIH Clinical and Translational Science Award (CTSA) in 2010, and its successful renewal in 2015, the UMCCTS joined a network of 62 NIH-funded centers collaborating to transform the conduct of clinical and translational research across the U.S. Other key partners include our patients and communities, foundations, biotechnology and pharmaceutical companies, and members of the venture capital and philanthropic communities. Our goals are to accelerate basic discoveries and develop and support the next generation in clinical and translational research. This collection showcases publications that are the result of UMCCTS supported research.

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Publications from 2015

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Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study), David D. McManus, Kahraman Tanriverdi, Honghuang Lin, Nada Esa, Menhel Kinno, Divakar Mandapati, Stanley Tam, Nsidinanya Okike, Patrick T. Ellinor, John F. Keaney, J. Kevin Donahue, Emelia J. Benjamin, and Jane E. Freedman

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Heterogeneity of postpartum depression: a latent class analysis, Postpartum Depression: Action Towards Causes and Treatment (PACT) Consortium, Kristina M. Deligiannidis, and Samantha Meltzer-Brody

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Variations in the implementation of acute care surgery: results from a national survey of university-affiliated hospitals, Heena Santry, John C. Madore, Courtney E. Collins, M. Didem Ayturk, George C. Velmahos, L. D. Britt, and Catarina I. Kiefe

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Follow-up compliance after endovascular abdominal aortic aneurysm repair in Medicare beneficiaries, Andres Schanzer, Louis M. Messina, Kaushik Ghosh, Jessica P. Simons, William P. Robinson III, Francesco A. Aiello, Robert J. Goldberg, and Allison B. Rosen

Publications from 2014

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Evaluating and selecting mobile health apps: strategies for healthcare providers and healthcare organizations, Edwin D. Boudreaux, Molly E. Waring, Rashelle B. Hayes, Rajani S. Sadasivam, Sean Mullen, and Sherry L. Pagoto

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Longitudinal association of anthropometric measures of adiposity with cardiometabolic risk factors in postmenopausal women, Geoffrey C. Kabat, Moonseong Heo, Linda V. Van Horn, Rasa Kazlauskaite, Asqual Getaneh, Jamy Ard, Mara Z. Vitolins, Molly E. Waring, Oleg Zaslavsky, Sylvia Wassertheil-Smoller, and Thomas E. Rohan

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Cognitive status in patients hospitalized with acute decompensated heart failure, Seth N. Levin, Alexandra M. Hajduk, David D. McManus, Chad E. Darling, Jerry H. Gurwitz, Frederick A. Spencer, Robert J. Goldberg, and Jane S. Saczynski

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Health literacy and pap testing in insured women, Kathleen M. Mazor, Andrew E. Williams, Douglas W. Roblin, Bridget Gaglio, Sarah L. Cutrona, Mary E. Costanza, Paul K. J. Han, Joann L. Wagner, Hassan Fouayzi, and Terry S. Field

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Medication adherence among pediatric patients with sickle cell disease: a systematic review, Kathleen E. Walsh, Sarah L. Cutrona, Patricia L. Kavanagh, Lori E. Crosby, Christopher Malone, Katie Lobner, and David G. Bundy

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Pregnant women's interest in a website or mobile application for healthy gestational weight gain, Molly E. Waring, Tiffany A. Moore Simas, Rui Sherry Xiao, Lisa Lombardini, Jeroan J. Allison, Milagros C. Rosal, and Sherry L. Pagoto

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Federated Aggregate Cohort Estimator (FACE): an easy to deploy, vendor neutral, multi-institutional cohort query architecture, Matthew C. Wyatt, R. Curtis Hendrickson, Michael Ames, Jessica Bondy, Paul Ranauro, Thomas M. English, Keith Bobitt, Arthur Davidson, Thomas K. Houston, Peter J. Embi, and Eta S. Berner

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Academic medical product development: an emerging alliance of technology transfer organizations and the CTSA, Lynn M. Rose, Maaike Everts, Caren Heller, Christine Burke, Nathaniel Hafer, and Scott Steele

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The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila, Qi Li, Sebastian Mana-Capelli, Rachel J. Roth Flach, Laura V. Danai, Alla Amcheslavsky, Yingchao Nie, Satoshi Kaneko, Xiaohao Yao, Xiaochu Chen, Jennifer L. Cotton, Junhao Mao, Dannel McCollum, Michael P. Czech, Lan Xu, and Y. Tony Ip

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The home environment and childhood obesity in low-income households: indirect effects via sleep duration and screen time, Bradley M. Appelhans, Stephanie L. Fitzpatrick, Hong Li, Vernon Cail, Molly E. Waring, Kristin L. Schneider, Matthew C. Whited, Andrew M. Busch, and Sherry L. Pagoto

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Statin discontinuation in nursing home residents with advanced dementia, Jennifer Tjia, Sarah L. Cutrona, Daniel Peterson, George W. Reed, Susan E. Andrade, and Susan L. Mitchell

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Depression and anxiety among high-risk obstetric inpatients, Nancy Byatt, Katherine Hicks-Courant, Autumn Davidson, Ruth Levesque, Eric O. Mick, Jeroan J. Allison, and Tiffany A. Moore Simas

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Tweeting it off: characteristics of adults who tweet about a weight loss attempt, Sherry L. Pagoto, Kristin L. Schneider, Martinus M. Evans, Molly E. Waring, Brad Appelhans, Andrew M. Busch, Matthew C. Whited, Herpreet Thind, and Michelle Ziedonis

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Planning and implementing a statewide soccer HIV awareness and health promotion intervention for African-born men living in the United States, Augustus Woyah, Chioma Nnaji, and Carol A. Bova

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The impact of sleep, stress, and depression on postpartum weight retention: A systematic review, Rui Sherry Xiao, Aimee R. Kroll-Desrosiers, Robert J. Goldberg, Sherry L. Pagoto, Sharina D. Person, and Molly E. Waring

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Healthy lifestyle and decreasing risk of heart failure in women: the Women's Health Initiative observational study, Golareh Agha, Eric B. Loucks, Lesley F. Tinker, Molly E. Waring, Dominique S. Michaud, Randi E. Foraker, Wenjun Li, Lisa W. Martin, Philip Greenland, JoAnn E. Manson, and Charles B. Eaton

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Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila, Alla Amcheslavsky, Wei Song, Qi Li, Yingchao Nie, Ivan Bragatto, Dominique Ferrandon, Norbert Perrimon, and Y. Tony Ip

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Effect of preinjury warfarin use on outcomes after head trauma in Medicare beneficiaries, Courtney E. Collins, Elan R. Witkowski, Julie Flahive, Frederick A. Anderson Jr., and Heena Santry

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Interleukin-6 and interleukin-10 gene promoter polymorphisms and risk of endemic burkitt lymphoma, Cliff I. Oduor, Kiprotich Chelimo, Collins Ouma, David H. Mulama, Joslyn Foley, John M. Vulule, Jeffrey A. Bailey, and Ann M. Moormann

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Long-term survival for patients with acute decompensated heart failure according to ejection fraction findings, Andrew H. Coles, Kimberly A. Fisher, Chad E. Darling, Jorge L. Yarzebski, David D. McManus, Joel M. Gore, Darleen M. Lessard, and Robert J. Goldberg

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What Happens to Mental Health Treatment During Pregnancy? Women's Experience with Prescribing Providers, Linda F. Weinreb, Nancy Byatt, Tiffany A. Moore Simas, Karen Tenner, and Judith A. Savageau

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TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis, Shiyan Yu, Yingchao Nie, Y. Tony Ip, and Nan Gao

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A population-based dietary inflammatory index predicts levels of C-reactive protein in the Seasonal Variation of Blood Cholesterol Study (SEASONS), Nitin Shivappa, Susan E. Steck, Thomas G. Hurley, James R. Hussey, Yunsheng Ma, Ira S. Ockene, Fred Tabung, and James R. Hebert

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Gene expression profiling identifies the zinc-finger protein Charlatan as a regulator of intestinal stem cells in Drosophila, Alla Amcheslavsky, Yingchao Nie, Qi Li, Feng He, Leo Tsuda, Michele Markstein, and Y. Tony Ip

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Trends in stroke rates, risk, and outcomes in the United States, 1988 to 2008, Margaret C. Fang, Marcelo Coca Perraillon, Kaushik Ghosh, David M. Cutler, and Allison B. Rosen

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Automatically Recognizing Medication and Adverse Event Information From Food and Drug Administration's Adverse Event Reporting System Narratives, Balaji Polepalli Ramesh, Steven M. Belknap, Zuofeng Li, Nadya Frid, Dennis P. West, and Hong Yu

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Psychometric evaluation of the care transition measure in TRACE-CORE: do we need a better measure, Milena D. Anatchkova, Constance M. Barysauskas, Rebecca L. Kinney, Catarina I. Kiefe, Arlene S. Ash, Lisa Lombardini, and Jeroan J. Allison

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Epidemiology and outcomes of community-acquired Clostridium difficile infections in Medicare beneficiaries, Courtney E. Collins, M. Didem Ayturk, Julie Flahive, Timothy A. Emhoff, Frederick A. Anderson Jr., and Heena Santry

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Surgeon volume and elective resection for colon cancer: an analysis of outcomes and use of laparoscopy, Rachelle N. Damle, Christopher W. Macomber, Julie M. Flahive, Jennifer S. Davids, W. Brian Sweeney, Paul R. Sturrock, Justin A. Maykel, Heena P. Santry, and Karim Alavi

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Rates of insurance for injured patients before and after health care reform in Massachusetts: a possible case of double jeopardy, Heena Santry, Courtney E. Collins, Jason T. Wiseman, Charles M. Psoinos, Julie Flahive, and Catarina I. Kiefe

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Not just full of hot air: hyperbaric oxygen therapy increases survival in cases of necrotizing soft tissue infections., Joshua J. Shaw, Charles M. Psoinos, Timothy A. Emhoff, Shimul A. Shah, and Heena Santry

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Decade-long trends in the magnitude, treatment, and outcomes of patients aged 30 to 54 years hospitalized with ST-segment elevation and non-ST-segment elevation myocardial infarction, Mayra Tisminetzky, Jennifer A. Coukos, David D. McManus, Chad E. Darling, Samuel W. Joffe, Joel M. Gore, Darleen M. Lessard, and Robert J. Goldberg

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Weight-based discrimination and medication adherence among low-income African Americans with hypertension: how much of the association is mediated by self-efficacy?, Michael P. Richardson, Molly E. Waring, Monica L. Wang, Lisa Nobel, Yendelela L. Cuffee, Sharina D. Person, Sandral Hullett, Catarina I. Kiefe, and Jeroan J. Allison

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Whole blood gene expression and atrial fibrillation: the Framingham Heart Study, Honghuang Lin, Xiaoyan Yin, Kathryn L. Lunetta, Josee Dupuis, David D. McManus, Steven A. Lubitz, Jared W. Magnani, Roby Joehanes, Peter J. Munson, Martin G. Larson, Daniel Levy, Patrick T. Ellinor, and Emelia J. Benjamin

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Individual and composite study endpoints: separating the wheat from the chaff, Robert J. Goldberg, Joel M. Gore, Bruce A. Barton, and Jerry H. Gurwitz

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An electronic health record-based intervention to increase follow-up office visits and decrease rehospitalization in older adults, Jerry H. Gurwitz, Terry S. Field, Jessica Ogarek, Jennifer Tjia, Sarah L. Cutrona, Leslie R. Harrold, Shawn J. Gagne, Peggy Preusse, Jennifer L. Donovan, Abir O. Kanaan, George W. Reed, and Lawrence D. Garber

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Galectin 3 and incident atrial fibrillation in the community, Jennifer E. Ho, Xiaoyan Yin, Daniel Levy, Ramachandran S. Vasan, Jared W. Magnani, Patrick T. Ellinor, David D. McManus, Steven A. Lubitz, Martin G. Larson, and Emelia J. Benjamin

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A qualitative analysis of acute care surgery in the United States: it's more than just "a competent surgeon with a sharp knife and a willing attitude", Heena Santry, Patricia L. Pringle, Courtney E. Collins, and Catarina I. Kiefe

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Decade-long trends in the characteristics, management and hospital outcomes of diabetic patients with ST-segment elevation myocardial infarction, Mayra Tisminetzky, Samuel W. Joffe, David D. McManus, Chad E. Darling, Joel M. Gore, Jorge L. Yarzebski, Darleen M. Lessard, and Robert J. Goldberg

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Early-treatment weight loss predicts 6-month weight loss in women with obesity and depression: Implications for stepped care, Molly E. Waring, Kristin L. Schneider, Bradley M. Appelhans, Andrew M. Busch, Matthew C. Whited, Stephanie Rodrigues, Stephenie C. Lemon, and Sherry L. Pagoto

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Differing patterns of selection and geospatial genetic diversity within two leading Plasmodium vivax candidate vaccine antigens, Christian M. Parobek, Jeffrey A. Bailey, Nicholas J. Hathaway, Duong Socheat, William O. Rogers, and Jonathan J. Juliano

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Electronic medical record: research tool for pancreatic cancer, Edward J. Arous, Theodore P. McDade, Jillian K. Smith, Sing Chau Ng, Mary E. Sullivan, Ralph J. Zottola, Paul J. Ranauro, Shimul A. Shah, Giles F. Whalen, and Jennifer F. Tseng

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Pharmacotherapy for Mood Disorders in Pregnancy: A Review of Pharmacokinetic Changes and Clinical Recommendations for Therapeutic Drug Monitoring, Kristina M. Deligiannidis, Nancy Byatt, and Marlene P. Freeman

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Systematic review of the use of online questionnaires of older adults, Meegan L. Remillard, Kathleen M. Mazor, Sarah L. Cutrona, Jerry H. Gurwitz, and Jennifer Tjia

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Epstein-barr virus latent membrane protein 1 genetic variability in peripheral blood B cells and oropharyngeal fluids, Nicholas Renzette, Mohan Somasundaran, Frank E. Brewster, James Coderre, Eric R. Weiss, Margaret M. McManus, Thomas C. Greenough, Barbara Tabak, Manuel Garber, Timothy F. Kowalik, and Katherine Ruiz De Luzuriaga

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The CTSA Consortium's Catalog of Assets for Translational and Clinical Health Research (CATCHR), Jana Shirey-Rice, Brandy Mapes, and Nathaniel Hafer

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30-year trends in patient characteristics, treatment practices, and long-term outcomes of adults aged 35 to 54 years hospitalized with acute myocardial infarction, Mayra Tisminetzky, David D. McManus, Joel M. Gore, Jorge L. Yarzebski, Andrew H. Coles, Darleen M. Lessard, and Robert J. Goldberg

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Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals, Stefan Washietl, Manolis Kellis, and Manuel Garber

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Retromer promotes immune quiescence by suppressing Spatzle-Toll pathway in Drosophila, Bo Zhou, Eun-Young Yun, Lorraine Ray, Jia You, Y. Tony Ip, and Xinhua Lin

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What is suppression of anti-adeno-associated virus capsid T-cells achieving, Terence R. Flotte and Christian Mueller

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Targeted sequencing in candidate genes for atrial fibrillation: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study, Honghuang Lin, Moritz F. Sinner, David D. McManus, Patrick T. Ellinor, Emelia J. Benjamin, and CHARGE Atrial Fibrillation Working Group

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National trends in pancreaticoduodenal trauma: interventions and outcomes, Elizaveta Ragulin-Coyne, Elan R. Witkowski, Zeling Chau, Daniel Wemple, Sing Chau Ng, Heena P. Santry, Shimul A. Shah, and Jennifer F. Tseng

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Urinary Isoflavone Concentrations Are Inversely Associated with Cardiometabolic Risk Markers in Pregnant U.S. Women, Ling Shi, Heather Harker Ryan, Emily Jones, Tiffany A. Moore Simas, Alice H. Lichtenstein, Qi Sun, and Laura L. Hayman

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The potential of adeno-associated viral vectors for gene delivery to muscle tissue, Dan Wang, Li Zhong, M. Abu Nahid, and Guangping Gao

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CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligo, Medhi Rashighi, Priti Agarwal, Jillian M. Richmond, Tajie H. Harris, Karen A. Dresser, Ming-Wan Su, Youwen Zhou, April Deng, Christopher A. Hunter, Andrew D. Luster, and John E. Harris

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Mediterranean and Dietary Approaches to Stop Hypertension dietary patterns and risk of sudden cardiac death in postmenopausal women, Monica L. Bertoia, Elizabeth W. Triche, Dominique S. Michaud, Ana Baylin, Joseph W. Hogan, Marian L. Neuhouser, Lesley F. Tinker, Linda Van Horn, Molly E. Waring, Wenjun Li, James M. Shikany, and Charles B. Eaton

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Gene expression and genetic variation in human atria, Honghuang Lin, Elena V. Dolmatova, Michael P. Morley, Kathryn L. Lunetta, David D. McManus, Jared W. Magnani, Kenneth B. Margulies, Hakon Hakonarson, Federica del Monte, Emelia J. Benjamin, Thomas P. Cappola, and Patrick T. Ellinor

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Sickle cell trait is not associated with endemic Burkitt lymphoma: an ethnicity and malaria endemicity-matched case-control study suggests factors controlling EBV may serve as a predictive biomarker for this pediatric cancer, David H. Mulama, Jeffrey A. Bailey, Joslyn Foley, Kiprotich Chelimo, Collins Ouma, Walter G.Z.O. Jura, Juliana A. Otieno, John M. Vulule, and Ann M. Moormann

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Pharmacokinetics, safety, and 48-week efficacy of oral raltegravir in HIV-1-infected children aged 2 through 18 years, Sharon Nachman and International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1066 Study Team

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Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis, Hongyan Wang, Bin Yang, Linghua Qiu, Chunxing Yang, Joshua Kramer, Qin Su, Yansu Guo, Robert H. Brown Jr., Guangping Gao, and Zuoshang Xu

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Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study, David D. McManus, Honghuang Lin, Kahraman Tanriverdi, Michael Quercio, Xiaoyan Yin, Martin G. Larson, Patrick T. Ellinor, Daniel Levy, Jane E. Freedman, and Emelia J. Benjamin

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Complementary and alternative medicine therapies for perinatal depression, Kristina M. Deligiannidis and Marlene P. Freeman

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Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach, Shuping Dou, Yuzhen Wang, Bruce A. Barton, Ling Chen, Mary Rusckowski, Leonard D. Shultz, Dale L. Greiner, and Guozheng Liu

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Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells, Nicola A. Kearns, Ryan M. J. Genga, Metewo Selase Enuameh, Manuel Garber, Scot A. Wolfe, and Rene Maehr

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Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation, Michiel Rienstra, Xiaoyan Yin, Martin G. Larson, Joao D. Fontes, Jared W. Magnani, David D. McManus, Elizabeth L. McCabe, Erin E. Coglianese, Michael Amponsah, Jennifer E. Ho, James L. Januzzi Jr., Kai C. Wollert, Michael G. Fradley, Ramachandran S. Vasan, Patrick T. Ellinor, Thomas J. Wang, and Emelia J. Benjamin

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Obesity and Late-Age Survival Without Major Disease or Disability in Older Women, Eileen Rillamas-Sun, Andrea Z. LaCroix, Molly E. Waring, Candyce H. Kroenke, Michael J. Lamonte, Mara Z. Vitolins, Rebecca A. Seguin, Christina L. Bell, Margery Gass, Todd M. Manini, Kamal H. Masaki, and Robert B. Wallace

Publications from 2013

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Institute of medicine 2009 gestational weight gain guideline knowledge: survey of obstetrics/gynecology and family medicine residents of the United States, Tiffany A. Moore Simas, Molly E. Waring, Gina M. T. Sullivan, Xun Liao, Milagros C. Rosal, Janet R. Hardy, and Robert E. Berry Jr.

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Challenges in sodium intake reduction and meal consumption patterns among participants with metabolic syndrome in a dietary trial, Jinsong Wang, Barbara C. Olendzki, Nicole M. Wedick, Gioia M. Persuitte, Annie L. Culver, Wenjun Li, Philip A. Merriam, James Carmody, Hua Julia Fang, Zhiying Zhang, Gin-Fei Olendzki, Liang Zheng, and Yunsheng Ma

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Genome-wide assessment of post-transcriptional control in the fly brain, Shaul Mezan, Reut Ashwal-Fluss, Rom Shenhav, Manuel Garber, and Sebastian Kadener

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Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression, Christian Mueller, Jeffrey D. Chulay, Bruce C. Trapnell, Margaret Humphries, Brenna Carey, Robert A. Sandhaus, Noel G. McElvaney, Louis M. Messina, Qiushi Tang, Farshid N. Rouhani, Martha Campbell-Thompson, Ann Dongtao Fu, Anthony Yachnis, David R. Knop, Guo-Jie Ye, Mark Brantly, Roberto Calcedo, Suryanarayan Somanathan, Lee P. Richman, Robert H. Vonderheide, Maigan A. Hulme, Todd M. Brusko, James M. Wilson, and Terence R. Flotte

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A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in canavan mice, Seemin Seher Ahmed, Huapeng Li, Chunyan Cao, Elif M. Sikoglu, Andrew R. Denninger, Qin Su, Samuel Eaton, Ana A. Liso Navarro, Jun Xie, Sylvia Szucs, Hongwei Zhang, Constance M. Moore, Daniel A. Kirschner, Thomas N. Seyfried, Terence R. Flotte, Reuben Matalon, and Guangping Gao

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Regulation of Toll signaling and inflammation by beta-arrestin and the SUMO protease Ulp1, Saima G. Anjum, Wenjian Xu, Niusha Nikkholgh, Sukanya Basu, Yingchao Nie, Mary Thomas, Mridula Satyamurti, Bogdan A. Budnik, Y. Tony Ip, and Alexey Veraksa

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Gudu, an Armadillo repeat-containing protein, is required for spermatogenesis in Drosophila, Wei Cheng, Y. Tony Ip, and Zuoshang Xu

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Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy, Carla E. Ransom, Yanling Huo, Kunjal Patel, Gwendolyn B. Scott, Heather D. Watts, Paige Williams, George K. Siberry, Elizabeth G. Livingston, and P1025 Team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group

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Implementing point of care "e-referrals" in 137 clinics to increase access to a quit smoking internet system: the Quit-Primo and National Dental PBRN HI-QUIT Studies, Rajani S. Sadasivam, Timothy P. Hogan, Julie E. Volkman, Bridget M. Smith, Heather L. Coley, Jessica H. Williams, Kathryn Delaughter, Midge N. Ray, Gregg H. Gilbert, Daniel E. Ford, Jeroan J. Allison, Thomas K. Houston, and National Dental PBRN and QUITPRIMO Collaborative Groups

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Beverage-consumption patterns and associations with metabolic risk factors among low-income Latinos with uncontrolled type 2 diabetes, Monica L. Wang, Stephenie C. Lemon, Barbara C. Olendzki, and Milagros C. Rosal

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Adult Willingness to Use Email and Social Media for Peer-to-Peer Cancer Screening Communication: Quantitative Interview Study, Sarah L. Cutrona, Douglas W. Roblin, Joann L. Wagner, Bridget Gaglio, Andrew E. Williams, Rosalie A. Torres Stone, Terry S. Field, and Kathleen M. Mazor

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All-Cause, Cardiovascular, and Cancer Mortality Rates in Postmenopausal White, Black, Hispanic, and Asian Women With and Without Diabetes in the United States: The Women's Health Initiative, 1993-2009, Yunsheng Ma, James R. Hebert, Raji Balasubramanian, Nicole M. Wedick, Barbara V. Howard, Milagros C. Rosal, Simin Liu, Chloe E. Bird, Barbara C. Olendzki, Judith K. Ockene, Jean Wactawski-Wende, Lawrence S. Phillips, Michael J. Lamonte, Kristin L. Schneider, Lorena Garcia, Ira S. Ockene, Philip A. Merriam, Deidre M. Sepavich, Rachel H. Mackey, Karen C. Johnson, and JoAnn E. Manson

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The impact of cardiac and noncardiac comorbidities on the short-term outcomes of patients hospitalized with acute myocardial infarction: a population-based perspective, Han-Yang Chen, Jane S. Saczynski, David D. McManus, Darleen M. Lessard, Jorge L. Yarzebski, Kate L. Lapane, Joel M. Gore, and Robert J. Goldberg

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Absence of detectable HIV-1 viremia after treatment cessation in an infant, Deborah Persaud, Hannah Gay, Carrie Ziemniak, Ya Hui Chen, Michael Piatak Jr., Tae-Wook Chun, Matthew Strain, Douglas Richman, and Katherine Luzuriaga

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Patient's views on depression care in obstetric settings: how do they compare to the views of perinatal health care professionals, Nancy Byatt, Kathleen Biebel, Liz Friedman, Gifty Debordes-Jackson, Douglas M. Ziedonis, and Lori Pbert

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Crowdsourced peer- versus expert-written smoking-cessation messages, Heather L. Coley, Rajani S. Sadasivam, Jessica H. Williams, Julie E. Volkman, Yu-Mei Schoenberger, Connie L. Kohler, Heather J. Sobko, Midge N. Ray, Jeroan J. Allison, Daniel E. Ford, Gregg H. Gilbert, Thomas K. Houston, and National Dental PBRN and QUITPRIMO Collaborative Group

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Parent support improves weight loss in adolescents and young adults with Down syndrome, Carol Curtin, Linda G. Bandini, Aviva Must, James Gleason, Keith Lividini, Sarah Phillips, Misha Eliasziw, Melissa C. T. Maslin, and Richard K. Fleming

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Adverse drug events after hospital discharge in older adults: types, severity, and involvement of Beers Criteria Medications, Abir O. Kanaan, Jennifer L. Donovan, Nerissa P. Duchin, Terry S. Field, Jennifer Tjia, Sarah L. Cutrona, Shawn J. Gagne, Lawrence D. Garber, Peggy Preusse, Leslie R. Harrold, and Jerry H. Gurwitz

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Patients' and family members' views on patient-centered communication during cancer care, Kathleen M. Mazor, Renee L. Beard, Gwen L. Alexander, Neeraj K. Arora, Cassandra L. Firneno, Bridget Gaglio, Sarah M. Greene, Celeste A. Lemay, Brandi E. Robinson, Douglas W. Roblin, Kathleen E. Walsh, Richard L. Street Jr., and Thomas H. Gallagher

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Relationship among circulating inflammatory proteins, platelet gene expression, and cardiovascular risk, David D. McManus, Lea M. Beaulieu, Eric Mick, Kahraman Tanriverdi, Martin G. Larson, John F. Keaney Jr., Emelia J. Benjamin, and Jane E. Freedman

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Randomized controlled trial of behavioral treatment for comorbid obesity and depression in women: the Be Active Trial, Sherry L. Pagoto, Kristin L. Schneider, Matthew C. Whited, Jessica L. Oleski, Philip A. Merriam, Bradley M. Appelhans, Yunsheng Ma, Barbara C. Olendzki, Molly E. Waring, A. M. Busch, Stephenie C. Lemon, Ira S. Ockene, and Sybil L. Crawford

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Utilization of morning report by acute care surgery teams: results from a qualitative study, Patricia L. Pringle, Courtney E. Collins, and Heena Santry

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Variations in tobacco control in National Dental PBRN practices: the role of patient and practice factors, Midge N. Ray, Jeroan J. Allison, Heather L. Coley, Jessica H. Williams, Connie L. Kohler, Gregg H. Gilbert, Joshua S. Richman, Catarina I. Kiefe, Rajani S. Sadasivam, Thomas K. Houston, and National DPBRN Collaborative Group

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Commonly used data-collection approaches in clinical research, Jane S. Saczynski, David D. McManus, and Robert J. Goldberg

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Assessing depression in obese women: An examination of two commonly-used measures, Kristin L. Schneider, Andrew M. Busch, Matthew C. Whited, Bradley M. Appelhans, Molly E. Waring, and Sherry L. Pagoto

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Specialization and utilization after hepatectomy in academic medical centers, Joshua J. Shaw, Heena Santry, and Shimul A. Shah

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Bending the cost curve? Results from a comprehensive primary care payment pilot, Sonal Vats, Arlene S. Ash, and Randall P. Ellis

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Validation of anaphylaxis in the Food and Drug Administration's Mini-Sentinel, Kathleen E. Walsh, Sarah L. Cutrona, Sarah Foy, Meghan A. Baker, Susan Forrow, Azadeh Shoaibi, Pamala A. Pawloski, Michelle Conroy, Andrew M. Fine, Lise E. Nigrovic, Nandini Selvam, Mano S. Selvan, William O. Cooper, and Susan E. Andrade

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Cognitive impairment and self-care in heart failure, Alexandra M. Hajduk, Stephenie C. Lemon, David D. McManus, Darleen M. Lessard, Jerry H. Gurwitz, Frederick A. Spencer, Robert J. Goldberg, and Jane S. Saczynski

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Physical activity and screen time in metabolically healthy obese phenotypes in adolescents and adults, Sarah M. Camhi, Molly E. Waring, Susan B. Sisson, Laura L. Hayman, and Aviva Must