The University of Massachusetts Center for Clinical and Translational Science (UMCCTS) was founded in 2006 to enhance clinical and translational research across the five University of Massachusetts campuses (Amherst, Boston, Dartmouth, Lowell, UMass Medical School) and our clinical partners, UMass Memorial Health Care and Baystate Medical Center. With the receipt of an NIH Clinical and Translational Science Award (CTSA) in 2010, and its successful renewal in 2015, the UMCCTS joined a network of 62 NIH-funded centers collaborating to transform the conduct of clinical and translational research across the U.S. Other key partners include our patients and communities, foundations, biotechnology and pharmaceutical companies, and members of the venture capital and philanthropic communities. Our goals are to accelerate basic discoveries and develop and support the next generation in clinical and translational research. This collection showcases publications that are the result of UMCCTS supported research.

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Publications from 2015

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Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome, Jeremy Shea, Ryan W. Serra, Benjamin R. Carone, Hennady P. Shulha, Alper Kucukural, Michael Ziller, Markus Vallaster, Hongcang Gu, Andrew R. Tapper, Paul D. Gardner, Alexander Meissner, Manuel Garber, and Oliver J. Rando

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Multiple Chronic Conditions and Psychosocial Limitations in Patients Hospitalized with an Acute Coronary Syndrome, Mayra Tisminetzky, Jerry H. Gurwitz, David D. McManus, Jane S. Saczynski, Nathaniel Erskine, Molly E. Waring, Milena D. Anatchkova, Hamza H. Awad, David C. Parish, Darleen M. Lessard, Catarina I. Kiefe, and Robert J. Goldberg

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DNA-binding-domain fusions enhance the targeting range and precision of Cas9, Mehmet Fatih Bolukbasi, Ankit Gupta, Sarah Oikemus, Alan G. Derr, Manuel Garber, Michael H. Brodsky, Lihua Julie Zhu, and Scot A. Wolfe

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iMStrong: Deployment of a Biosensor System to Detect Cocaine Use, Stephanie Carreiro, Hua (Julia) Fang, Jianying Zhang, Kelley Wittbold, Shicheng Weng, Rachel Mullins, David A. Smelson, and Edward W. Boyer

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MicroRNAs in platelet function and cardiovascular disease, David D. McManus and Jane Freedman

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Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila, Yingchao Nie, Qi Li, Alla Amcheslavsky, Juan Carlos Duhart, Alexey Veraksa, Hugo Stocker, Laurel A. Raftery, and Y. Tony Ip

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Measuring Diversity and Inclusion in Academic Medicine: The Diversity Engagement Survey, Sharina D. Person, C. Greer Jordan, Jeroan J. Allison, Lisa M. Fink Ogawa, Laura Castillo-Page, Sarah Conrad, Marc A. Nivet, and Deborah L. Plummer

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Trends in acute myocardial infarction hospitalizations: Are we seeing the whole picture, Naomi C. Sacks, Arlene S. Ash, Kaushik Ghosh, Amy K. Rosen, John B. Wong, and Allison B. Rosen

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Addition of B-Type Natriuretic Peptide to Existing Clinical Risk Scores Enhances Identification of Patients at Risk for Atrial Fibrillation Recurrence After Pulmonary Vein Isolation, Amir Y. Shaikh, Nada Esa, William Martin-Doyle, Menhel Kinno, Iryna Nieto, Kevin C. Floyd, Clifford Browning, Cynthia Ennis, J. Kevin Donahue, Lawrence S. Rosenthal, and David D. McManus

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Psychiatric gene discoveries shape evidence on ADHD's biology, Anita Thapar, J. Martin, Eric Mick, A. Arias Vasquez, Kate Langley, Stephen W. Scherer, Russell Schachar, Jennifer Crosbie, N. Williams, Barbara Franke, J. Elia, J. Glessner, H. Hakonarson, M. J. Owen, S. V. Faraone, Michael C. O'Donovan, and Peter Holmans

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Decade-Long Trends in 30-Day Rehospitalization Rates After Acute Myocardial Infarction, Han-Yang Chen, Mayra Tisminetzky, Kate L. Lapane, Jorge L. Yarzebski, Sharina D. Person, Catarina I. Kiefe, Joel Gore, and Robert J. Goldberg

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Evaluating the QUIT-PRIMO clinical practice ePortal to increase smoker engagement with online cessation interventions: a national hybrid type 2 implementation study, Thomas K. Houston, Rajani S. Sadasivam, Jeroan J. Allison, Arlene S. Ash, Midge N. Ray, Thomas M. English, Timothy P. Hogan, and Daniel E. Ford

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Enhancing Participation in Depression Care in Outpatient Perinatal Care Settings: A Systematic Review, Nancy Byatt, Len L. Levin, Douglas M. Ziedonis, Tiffany A. Moore Simas, and Jeroan J. Allison

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A Gene Expression Signature That Correlates with CD8+ T Cell Expansion in Acute EBV Infection, Thomas C. Greenough, Juerg R. Straubhaar, Larisa Kamga, Eric R. Weiss, Robin M. Brody, Margaret M. McManus, Linda K. Lambrecht, Mohan Somasundaran, and Katherine Ruiz De Luzuriaga

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Who Gets Early Tracheostomy?: Evidence of Unequal Treatment at 185 Academic Medical Centers, Joshua J. Shaw and Heena Santry

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Perceiving one's heart condition to be cured following hospitalization for acute coronary syndromes: Implications for patient-provider communication, Molly E. Waring, David D. McManus, Stephenie C. Lemon, Joel M. Gore, Milena D. Anatchkova, Richard H. McManus, Arlene S. Ash, Robert J. Goldberg, Catarina I. Kiefe, and Jane S. Saczynski

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Narratives to enhance smoking cessation interventions among African-American smokers, the ACCE project, Andrea Cherrington, Jessica H. Williams, Pamela Payne Foster, Heather L. Coley, Connie Kohler, Jeroan J. Allison, Catarina I. Kiefe, Julie E. Volkman, and Thomas K. Houston

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Safety of Striatal Infusion of siRNA in a Transgenic Huntington's Disease Mouse Model, Emily S. Johnson, Kathryn O. Chase, Sarah McGowan, Erica Mondo, Edith L. Pfister, Eric Mick, Randall H. Friedline, Jason K. Kim, Ellen Sapp, Marian DiFiglia, and Neil Aronin

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Risk Factors for Relapse and Higher Costs Among Medicaid Members with Opioid Dependence or Abuse: Opioid Agonists, Comorbidities, and Treatment History, Robin E. Clark, Jeffrey D. Baxter, Gideon Aweh, Elizabeth O'Connell, William H. Fisher, and Bruce A. Barton

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Evaluating Academic Scientists Collaborating in Team-Based Research: A Proposed Framework, Madhu Mazumdar; Shari Messinger; Dianne M. Finkelstein; Judith D. Goldberg; Christopher J. Lindsell; Sally C. Morton; Brad H. Pollock; Mohammad H. Rahbar; L. J. Welty; Robert A. Parker; and Biostatistics, Epidemiology, and Research Design (BERD) Key Function Committee of the Clinical and Translational Science Awards (CTSA) Consortium.

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Atrial Fibrillation and Hypertension: Mechanistic, Epidemiologic, and Treatment Parallels, Adedotun Ogunsua, Amir Y. Shaikh, Mohamed Ahmed, and David D. McManus

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A Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Metformin Therapy in Overweight/Obese Youth with Type 1 Diabetes, Benjamin U. Nwosu, Louise Maranda, Karen Cullen, Lisa Greenman, Jody Fleshman, Nancy McShea, Bruce A. Barton, and Mary M. Lee

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On the relative roles of background selection and genetic hitchhiking in shaping human cytomegalovirus genetic diversity, Nicholas Renzette, Timothy F. Kowalik, and Jeffrey D. Jensen

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Attitudes toward Substance Abuse Clients: An Empirical Study of Clinical Psychology Trainees, Chandra R. Mundon, Melissa L. Anderson, and Lisa M. Najavits

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Modeling Epidemics Spreading on Social Contact Networks, Zhaoyang Zhang, Honggang Wang, Chonggang Wang, and Hua (Julia) Fang

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Innovation or rebranding, acute care surgery diffusion will continue, Courtney E. Collins, Patricia L. Pringle, and Heena Santry

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Testing item response theory invariance of the standardized Quality-of-life Disease Impact Scale (QDIS) in acute coronary syndrome patients: differential functioning of items and test, Nina Deng, Milena D. Anatchkova, Molly E. Waring, Kyung T. Han, and John E. Ware Jr.

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The impact of acute care surgery on appendicitis outcomes: Results from a national sample of university-affiliated hospitals, John C. Madore, Courtney E. Collins, M. Didem Ayturk, and Heena Santry

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Decision Aids and Shared Decision-Making in Neurocritical Care: An Unmet Need in Our NeuroICUs, Susanne Muehlschlegel, Lori Shutter, Nananda Col, and Robert J. Goldberg

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50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study, Renate B. Schnabel, Philimon Gona, and David D. McManus

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Data from: A Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Metformin Therapy in Overweight/Obese Youth with Type 1 Diabetes, Benjamin U. Nwosu, Louise Maranda, Karen Cullen, Lisa Greenman, Jody Fleshman, Nancy McShea, Bruce A. Barton, and Mary M. Lee

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Thirty day hospital re-admissions in patients with non ST-segment elevation acute myocardial infarction, Mayra Tisminetzky, David D. McManus, Nathaniel Erskine, Jane S. Saczynski, Jorge L. Yarzebski, Edgard A. Granillo, Joel Gore, and Robert J. Goldberg

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Smoking Topography in Korean American and White Men: Preliminary Findings, Sangkeun Chung, Sun S. Kim, Nisha Kini, Hua (Julia) Fang, David Kalman, and Douglas M. Ziedonis

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The Complex Relationship of Race to Outcomes in Heart Failure with Preserved Ejection Fraction, Jerry H. Gurwitz, David J. Magid, David H. Smith, Grace Hsu, Sue Hee Sung, Larry A. Allen, David D. McManus, Robert J. Goldberg, and Alan S. Go

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Recombinant adeno-associated virus-mediated inhibition of microRNA-21 protects mice against the lethal schistosome infection by repressing both IL-13 and transforming growth factor beta 1 pathways, Xing He, Jun Xie, Dongmei Zhang, Qin Su, Xue Sai, Ruipu Bai, Chao Chen, Xufeng Luo, Guangping Gao, and Weiqing Pan

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Quadrimodal distribution of death after trauma suggests that critical injury is a potentially terminal disease, Heena Santry, Charles M. Psoinos, Christopher J. Wilbert, Julie Flahive, Aimee Kroll, Timothy A. Emhoff, and Catarina I. Kiefe

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Pregnancy intention, receipt of pre-conception care, and pre-conception weight counseling reported by overweight and obese women in late pregnancy, Molly E. Waring, Tiffany A. Moore Simas, Milagros C. Rosal, and Sherry L. Pagoto

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Characteristics of Contemporary Patients Discharged From the Hospital After an Acute Coronary Syndrome, Robert J. Goldberg, Jane S. Saczynski, David D. McManus, Molly E. Waring, Richard H. McManus, Jeroan J. Allison, David C. Parish, Darleen M. Lessard, Sharina D. Person, Joel Gore, and Catarina I. Kiefe

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Working Therapeutically With Deaf People Recovering From Trauma and Addiction, Melissa L. Anderson, Neil S. Glickman, Lisa Mistler, and Marco Gonzalez

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DeTEXT: A Database for Evaluating Text Extraction from Biomedical Literature Figures, Xu-Cheng Yin, Chun Yang, Wei-Yi Pei, Haixia Man, Jun Zhang, Erik Learned-Miller, and Hong Yu

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Decisional Capacity in Pregnancy: A Complex Case of Pregnancy Termination, Isheeta Zalpuri, Nancy Byatt, Stacey B. Gramann, Nehama Dresner, and Rebecca Brendel

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Declining Long-term Risk of Adverse Events after First-time Community-presenting Venous Thromboembolism: The Population-based Worcester VTE Study (1999 to 2009), Wei Huang, Robert J. Goldberg, A. T. Cohen, Frederick A. Anderson Jr., Catarina I. Kiefe, Joel M. Gore, and Frederick A. Spencer

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Reduced frequencies of polyfunctional CMV-specific T cell responses in infants with congenital CMV infection, Laura L. Gibson, Constance Barysauskas, Margaret M. McManus, Sheryl Dooley, Daniele Lilleri, Donna Fisher, Tumul Srivastava, Don J. Diamond, and Katherine Ruiz De Luzuriaga

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Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses, Tianxiao Huan, Jian Rong, Kahraman Tanriverdi, Qingying Meng, Anindya Bhattacharya, David D. McManus, Roby Joehanes, Themistocles L. Assimes, Ruth McPherson, Nilesh J. Samani, Jeanette Erdmann, Heribert Schunkert, Paul Courchesne, Peter J. Munson, Andrew D. Johnson, Christopher J. O'Donnell, Bin Zhang, Martin G. Larson, Jane Freedman, Daniel Levy, and Xia Yang

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Tobacco counseling experience prior to starting medical school, tobacco treatment self-efficacy and knowledge among first-year medical students in the United States, Rui Sherry Xiao, Rashelle B. Hayes, Molly E. Waring, Alan C. Geller, Linda C. Churchill, Kolawole S. Okuyemi, Michael Adams, Kathryn N. Huggett, and Judith K. Ockene

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Characterization of functional antibody and memory B-cell responses to pH1N1 monovalent vaccine in HIV-infected children and youth, Donna J. Curtis, Petronella Muresan, Sharon Nachman, Terence Fenton, Kelly M. Richardson, Teresa Dominguez, Patricia M. Flynn, Stephen A. Spector, Coleen K. Cunningham, Anthony Bloom, and Adriana Weinberg

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Health information-seeking on behalf of others: characteristics of "surrogate seekers", Sarah L. Cutrona, Kathleen M. Mazor, Sana N. Vieux, Tana M. Luger, Julie E. Volkman, and Lila J. Finney Rutten

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Current status of gene therapy for alpha-1 antitrypsin deficiency, Heather S. Loring and Terence R. Flotte

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An online social network to increase walking in dog owners: a randomized trial, Kristin L. Schneider, Deirdra Murphy, Cynthia Ferrara, Jessica L. Oleski, Emily Panza, Clara Savage, Brianne Bozzella, Effie Olendzki, Daniel Kern, Stephenie C. Lemon, and Kimberly Gada

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Absence of Putative Artemisinin Resistance Mutations Among Plasmodium falciparum in Sub-Saharan Africa: A Molecular Epidemiologic Study, Steve M. Taylor, Derrick K. DeConti, Ann M. Moormann, Jeffrey A. Bailey, and Jonathan J. Juliano

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Cluster-based Epidemic Control Through Smartphone-based Body Area Networks, Zhaoyang Zhang, Honggang Wang, Chonggang Wang, and Hua (Julia) Fang

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A bridge too far? Findings of bridging anticoagulation use and outcomes in the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF), Amir Y. Shaikh and David D. McManus

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A television in the bedroom is associated with higher weekday screen time among youth with attention deficit hyperactivity disorder (ADD/ADHD), Charmaine B. Lo, Molly E. Waring, Sherry L. Pagoto, and Stephenie C. Lemon

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Exposure to selective serotonin reuptake inhibitors in late pregnancy increases the risk of persistent pulmonary hypertension of the newborn, but the absolute risk is low, Nancy Byatt and Marlene P. Freeman

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Predictors and outcomes of readmission for Clostridium difficile in a national sample of medicare beneficiaries, Courtney E. Collins, M. Didem Ayturk, Frederick A. Anderson Jr., and Heena Santry

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Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study), David D. McManus, Kahraman Tanriverdi, Honghuang Lin, Nada Esa, Menhel Kinno, Divakar Mandapati, Stanley Tam, Nsidinanya Okike, Patrick T. Ellinor, John F. Keaney, J. Kevin Donahue, Emelia J. Benjamin, and Jane E. Freedman

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Heterogeneity of postpartum depression: a latent class analysis, Postpartum Depression: Action Towards Causes and Treatment (PACT) Consortium, Kristina M. Deligiannidis, and Samantha Meltzer-Brody

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Variations in the implementation of acute care surgery: results from a national survey of university-affiliated hospitals, Heena Santry, John C. Madore, Courtney E. Collins, M. Didem Ayturk, George C. Velmahos, L. D. Britt, and Catarina I. Kiefe

Publications from 2014

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Cognitive status in patients hospitalized with acute decompensated heart failure, Seth N. Levin, Alexandra M. Hajduk, David D. McManus, Chad E. Darling, Jerry H. Gurwitz, Frederick A. Spencer, Robert J. Goldberg, and Jane S. Saczynski

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Health literacy and pap testing in insured women, Kathleen M. Mazor, Andrew E. Williams, Douglas W. Roblin, Bridget Gaglio, Sarah L. Cutrona, Mary E. Costanza, Paul K. J. Han, Joann L. Wagner, Hassan Fouayzi, and Terry S. Field

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Pregnant women's interest in a website or mobile application for healthy gestational weight gain, Molly E. Waring, Tiffany A. Moore Simas, Rui Sherry Xiao, Lisa Lombardini, Jeroan J. Allison, Milagros C. Rosal, and Sherry L. Pagoto

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Academic medical product development: an emerging alliance of technology transfer organizations and the CTSA, Lynn M. Rose, Maaike Everts, Caren Heller, Christine Burke, Nathaniel Hafer, and Scott Steele

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HIV Stigma, Testing Attitudes and Health Care Access Among African-Born Men Living in the United States, Carol A. Bova, Chioma Nnaji, Augustus Woyah, and Akwasi Duah

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Depression and anxiety among high-risk obstetric inpatients, Nancy Byatt, Katherine Hicks-Courant, Autumn Davidson, Ruth Levesque, Eric O. Mick, Jeroan J. Allison, and Tiffany A. Moore Simas

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Planning and implementing a statewide soccer HIV awareness and health promotion intervention for African-born men living in the United States, Augustus Woyah, Chioma Nnaji, and Carol A. Bova

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The impact of sleep, stress, and depression on postpartum weight retention: A systematic review, Rui Sherry Xiao, Aimee R. Kroll-Desrosiers, Robert J. Goldberg, Sherry L. Pagoto, Sharina D. Person, and Molly E. Waring

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Healthy lifestyle and decreasing risk of heart failure in women: the Women's Health Initiative observational study, Golareh Agha, Eric B. Loucks, Lesley F. Tinker, Molly E. Waring, Dominique S. Michaud, Randi E. Foraker, Wenjun Li, Lisa W. Martin, Philip Greenland, JoAnn E. Manson, and Charles B. Eaton

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Effect of preinjury warfarin use on outcomes after head trauma in Medicare beneficiaries, Courtney E. Collins, Elan R. Witkowski, Julie Flahive, Frederick A. Anderson Jr., and Heena Santry

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Interleukin-6 and interleukin-10 gene promoter polymorphisms and risk of endemic burkitt lymphoma, Cliff I. Oduor, Kiprotich Chelimo, Collins Ouma, David H. Mulama, Joslyn Foley, John M. Vulule, Jeffrey A. Bailey, and Ann M. Moormann

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Long-term survival for patients with acute decompensated heart failure according to ejection fraction findings, Andrew H. Coles, Kimberly A. Fisher, Chad E. Darling, Jorge L. Yarzebski, David D. McManus, Joel M. Gore, Darleen M. Lessard, and Robert J. Goldberg

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What Happens to Mental Health Treatment During Pregnancy? Women's Experience with Prescribing Providers, Linda F. Weinreb, Nancy Byatt, Tiffany A. Moore Simas, Karen Tenner, and Judith A. Savageau

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A population-based dietary inflammatory index predicts levels of C-reactive protein in the Seasonal Variation of Blood Cholesterol Study (SEASONS), Nitin Shivappa, Susan E. Steck, Thomas G. Hurley, James R. Hussey, Yunsheng Ma, Ira S. Ockene, Fred Tabung, and James R. Hebert

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Trends in stroke rates, risk, and outcomes in the United States, 1988 to 2008, Margaret C. Fang, Marcelo Coca Perraillon, Kaushik Ghosh, David M. Cutler, and Allison B. Rosen

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Angiogenic biomarkers for prediction of early preeclampsia onset in high-risk women, Tiffany A. Moore Simas, Sybil L. Crawford, Susanne Bathgate, Jing Yan, Laura Robidoux, Melissa J. Moore, and Sharon E. Maynard

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Psychometric evaluation of the care transition measure in TRACE-CORE: do we need a better measure, Milena D. Anatchkova, Constance M. Barysauskas, Rebecca L. Kinney, Catarina I. Kiefe, Arlene S. Ash, Lisa Lombardini, and Jeroan J. Allison

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Epidemiology and outcomes of community-acquired Clostridium difficile infections in Medicare beneficiaries, Courtney E. Collins, M. Didem Ayturk, Julie Flahive, Timothy A. Emhoff, Frederick A. Anderson Jr., and Heena Santry

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Surgeon volume and elective resection for colon cancer: an analysis of outcomes and use of laparoscopy, Rachelle N. Damle, Christopher W. Macomber, Julie M. Flahive, Jennifer S. Davids, W. Brian Sweeney, Paul R. Sturrock, Justin A. Maykel, Heena P. Santry, and Karim Alavi

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Rates of insurance for injured patients before and after health care reform in Massachusetts: a possible case of double jeopardy, Heena Santry, Courtney E. Collins, Jason T. Wiseman, Charles M. Psoinos, Julie Flahive, and Catarina I. Kiefe

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Not just full of hot air: hyperbaric oxygen therapy increases survival in cases of necrotizing soft tissue infections., Joshua J. Shaw, Charles M. Psoinos, Timothy A. Emhoff, Shimul A. Shah, and Heena Santry

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Decade-long trends in the magnitude, treatment, and outcomes of patients aged 30 to 54 years hospitalized with ST-segment elevation and non-ST-segment elevation myocardial infarction, Mayra Tisminetzky, Jennifer A. Coukos, David D. McManus, Chad E. Darling, Samuel W. Joffe, Joel M. Gore, Darleen M. Lessard, and Robert J. Goldberg

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Weight-based discrimination and medication adherence among low-income African Americans with hypertension: how much of the association is mediated by self-efficacy?, Michael P. Richardson, Molly E. Waring, Monica L. Wang, Lisa Nobel, Yendelela L. Cuffee, Sharina D. Person, Sandral Hullett, Catarina I. Kiefe, and Jeroan J. Allison

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Whole blood gene expression and atrial fibrillation: the Framingham Heart Study, Honghuang Lin, Xiaoyan Yin, Kathryn L. Lunetta, Josee Dupuis, David D. McManus, Steven A. Lubitz, Jared W. Magnani, Roby Joehanes, Peter J. Munson, Martin G. Larson, Daniel Levy, Patrick T. Ellinor, and Emelia J. Benjamin

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Individual and composite study endpoints: separating the wheat from the chaff, Robert J. Goldberg, Joel M. Gore, Bruce A. Barton, and Jerry H. Gurwitz

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An electronic health record-based intervention to increase follow-up office visits and decrease rehospitalization in older adults, Jerry H. Gurwitz, Terry S. Field, Jessica Ogarek, Jennifer Tjia, Sarah L. Cutrona, Leslie R. Harrold, Shawn J. Gagne, Peggy Preusse, Jennifer L. Donovan, Abir O. Kanaan, George W. Reed, and Lawrence D. Garber

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Galectin 3 and incident atrial fibrillation in the community, Jennifer E. Ho, Xiaoyan Yin, Daniel Levy, Ramachandran S. Vasan, Jared W. Magnani, Patrick T. Ellinor, David D. McManus, Steven A. Lubitz, Martin G. Larson, and Emelia J. Benjamin

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A qualitative analysis of acute care surgery in the United States: it's more than just "a competent surgeon with a sharp knife and a willing attitude", Heena Santry, Patricia L. Pringle, Courtney E. Collins, and Catarina I. Kiefe

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Decade-long trends in the characteristics, management and hospital outcomes of diabetic patients with ST-segment elevation myocardial infarction, Mayra Tisminetzky, Samuel W. Joffe, David D. McManus, Chad E. Darling, Joel M. Gore, Jorge L. Yarzebski, Darleen M. Lessard, and Robert J. Goldberg

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Early-treatment weight loss predicts 6-month weight loss in women with obesity and depression: Implications for stepped care, Molly E. Waring, Kristin L. Schneider, Bradley M. Appelhans, Andrew M. Busch, Matthew C. Whited, Stephanie Rodrigues, Stephenie C. Lemon, and Sherry L. Pagoto

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Differing patterns of selection and geospatial genetic diversity within two leading Plasmodium vivax candidate vaccine antigens, Christian M. Parobek, Jeffrey A. Bailey, Nicholas J. Hathaway, Duong Socheat, William O. Rogers, and Jonathan J. Juliano

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Electronic medical record: research tool for pancreatic cancer, Edward J. Arous, Theodore P. McDade, Jillian K. Smith, Sing Chau Ng, Mary E. Sullivan, Ralph J. Zottola, Paul J. Ranauro, Shimul A. Shah, Giles F. Whalen, and Jennifer F. Tseng

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Pharmacotherapy for Mood Disorders in Pregnancy: A Review of Pharmacokinetic Changes and Clinical Recommendations for Therapeutic Drug Monitoring, Kristina M. Deligiannidis, Nancy Byatt, and Marlene P. Freeman

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Epstein-barr virus latent membrane protein 1 genetic variability in peripheral blood B cells and oropharyngeal fluids, Nicholas Renzette, Mohan Somasundaran, Frank E. Brewster, James Coderre, Eric R. Weiss, Margaret M. McManus, Thomas C. Greenough, Barbara Tabak, Manuel Garber, Timothy F. Kowalik, and Katherine Ruiz De Luzuriaga

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The CTSA Consortium's Catalog of Assets for Translational and Clinical Health Research (CATCHR), Jana Shirey-Rice, Brandy Mapes, and Nathaniel Hafer

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Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals, Stefan Washietl, Manolis Kellis, and Manuel Garber

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What is suppression of anti-adeno-associated virus capsid T-cells achieving, Terence R. Flotte and Christian Mueller

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Targeted sequencing in candidate genes for atrial fibrillation: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study, Honghuang Lin, Moritz F. Sinner, David D. McManus, Patrick T. Ellinor, Emelia J. Benjamin, and CHARGE Atrial Fibrillation Working Group

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National trends in pancreaticoduodenal trauma: interventions and outcomes, Elizaveta Ragulin-Coyne, Elan R. Witkowski, Zeling Chau, Daniel Wemple, Sing Chau Ng, Heena P. Santry, Shimul A. Shah, and Jennifer F. Tseng

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Urinary Isoflavone Concentrations Are Inversely Associated with Cardiometabolic Risk Markers in Pregnant U.S. Women, Ling Shi, Heather Harker Ryan, Emily Jones, Tiffany A. Moore Simas, Alice H. Lichtenstein, Qi Sun, and Laura L. Hayman

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The potential of adeno-associated viral vectors for gene delivery to muscle tissue, Dan Wang, Li Zhong, M. Abu Nahid, and Guangping Gao

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Mediterranean and Dietary Approaches to Stop Hypertension dietary patterns and risk of sudden cardiac death in postmenopausal women, Monica L. Bertoia, Elizabeth W. Triche, Dominique S. Michaud, Ana Baylin, Joseph W. Hogan, Marian L. Neuhouser, Lesley F. Tinker, Linda Van Horn, Molly E. Waring, Wenjun Li, James M. Shikany, and Charles B. Eaton