UMMS Affiliation
Program in Molecular Medicine
Publication Date
2015-02-19
Document Type
Article
Disciplines
Infectious Disease | Maternal and Child Health | Therapeutics | Translational Medical Research | Virus Diseases | Viruses
Abstract
We previously reported the remission of human immunodeficiency virus type 1 (HIV-1) in a perinatally infected child — the “Mississippi Child.” After receiving antiretroviral therapy (ART) between 30 hours and 18 months of age, this child had persistently undetectable plasma HIV-1 viremia for 12 months in the absence of HIV-1–specific immune responses. At the time of the initial case report, it was uncertain whether HIV-1 reservoirs were established that could lead to rebound viremia.
Keywords
UMCCTS funding
Rights and Permissions
Publisher PDF posted after 6 months as allowed by publisher's Author Permissions policy at: https://www.nejm.org/author-center/permissions
DOI of Published Version
10.1056/NEJMc1413931
Source
N Engl J Med. 2015 Feb 19;372(8):786-8. doi: 10.1056/NEJMc1413931. Link to article on publisher's site
Journal/Book/Conference Title
The New England journal of medicine
Related Resources
PubMed ID
25693029
Repository Citation
Luzuriaga, Katherine; Gay, Hannah; Ziemniak, Carrie; Sanborn, Keri B.; Somasundaran, Mohan; Rainwater-Lovett, Kaitlin; Mellors, John W.; Rosenbloom, Daniel; and Persaud, Deborah, "Viremic relapse after HIV-1 remission in a perinatally infected child" (2015). UMass Center for Clinical and Translational Science Supported Publications. 183.
https://escholarship.umassmed.edu/umccts_pubs/183
Included in
Infectious Disease Commons, Maternal and Child Health Commons, Therapeutics Commons, Translational Medical Research Commons, Virus Diseases Commons, Viruses Commons