UMMS Affiliation
School of Medicine; Department of Medicine, Division of Cardiovascular Medicine
Publication Date
2017-6
Document Type
Article
Disciplines
Cardiology | Cardiovascular Diseases | Mental and Social Health | Psychiatry and Psychology | Translational Medical Research
Abstract
BACKGROUND: Impairments in psychosocial status and cognition relate to poor clinical outcomes in patients with atrial fibrillation (AF). However, how often these conditions co-occur and associations between burden of psychosocial and cognitive impairment and quality of life (QoL) have not been systematically examined in patients with AF.
METHODS: A total of 218 patients with symptomatic AF were enrolled in a prospective study of AF and psychosocial factors between May 2013 and October 2014 at the University of Massachusetts Medical Center. Cognitive function, depression, and anxiety were assessed at baseline and AF-specific QoL was assessed 6 months after enrollment using validated instruments. Demographic and clinical information were obtained from a structured interview and medical record review.
RESULTS: The mean age of the study participants was 63.5 +/- 10.2 years, 35% were male, and 81% had paroxysmal AF. Prevalences of impairment in 1, 2, and 3 psychosocial/cognitive domains (eg, depression, anxiety, or cognition) were 75 (34.4%), 51 (23.4%), and 16 (7.3%), respectively. Patients with co-occurring psychosocial/cognitive impairments (eg, > 1 domain) were older, more likely to smoke, had less education, and were more likely to have heart failure (all P < 0.05). Compared with participants with no psychosocial/cognitive impairments, AF-specific QoL at 6 months was significantly poorer among participants with baseline impairment in 2 (B = -13.6, 95% CI: -21.7 to -5.4) or 3 (B = -15.1, 95% CI: -28.0 to -2.2) psychosocial/cognitive domains.
CONCLUSION: Depression, anxiety, and impaired cognition were common in our cohort of patients with symptomatic AF and often co-occurred. Higher burden of psychosocial/cognitive impairment was associated with poorer AF-specific QoL.
Keywords
UMCCTS funding
DOI of Published Version
10.1097/HPC.0000000000000101
Source
Crit Pathw Cardiol. 2017 Jun;16(2):71-75. doi: 10.1097/HPC.0000000000000101. Link to article on publisher's site
Journal/Book/Conference Title
Critical pathways in cardiology
Related Resources
PubMed ID
28509707
Repository Citation
Bostrom, John A.; Saczynski, Jane S.; Hajduk, Alexandra M.; Donahue, Kevin; Rosenthal, Lawrence S.; Browning, Clifford; Ennis, Cynthia; Floyd, Kevin C.; Richardson, Heather; Esa, Nada; Ogarek, Jessica; and McManus, David D., "Burden of Psychosocial and Cognitive Impairment in Patients With Atrial Fibrillation" (2017). UMass Center for Clinical and Translational Science Supported Publications. 115.
https://escholarship.umassmed.edu/umccts_pubs/115
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Included in
Cardiology Commons, Cardiovascular Diseases Commons, Mental and Social Health Commons, Psychiatry and Psychology Commons, Translational Medical Research Commons
Comments
John Bostrom is a medical student at the University of Massachusetts Medical School.