Authors
Dekker, JobUMass Chan Affiliations
Department of Biochemistry and Molecular PharmacologyProgram in Systems Biology
Document Type
Response or CommentPublication Date
2016-11-21Keywords
Chromosome conformation capture-based methodsMicroscopy
Nuclear organization
Biochemistry, Biophysics, and Structural Biology
Cell Biology
Genetics and Genomics
Systems Biology
Metadata
Show full item recordAbstract
The spatial organization of genomes is studied using microscopy- and chromosome conformation capture (3C)-based methods. The two types of methods produce data that are often consistent, but there are cases where they appear discordant. These cases provide opportunities to derive better models of chromatin folding, which can reconcile the datasets.Source
Nat Rev Mol Cell Biol. 2016 Nov 21;17(12):741-742. doi: 10.1038/nrm.2016.151. Link to article on publisher's siteDOI
10.1038/nrm.2016.151Permanent Link to this Item
http://hdl.handle.net/20.500.14038/49974PubMed ID
27869158Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1038/nrm.2016.151