Title

HiTC : Exploration of High-Throughput 'C' experiments

UMMS Affiliation

Program in Systems Biology

Publication Date

11-1-2012

Document Type

Article

Subjects

Chromosome Positioning; Chromosomes; DNA; Genomics; Nucleic Acid Conformation; Genetic Techniques

Disciplines

Bioinformatics | Genetics and Genomics | Systems Biology

Abstract

The R/Bioconductor package HiTC facilitates the exploration of high-throughtput 3C-based data. It allows users to import and export 'C' data, to transform, normalize, annotate and visualize interaction maps. The package operates within the Bioconductor framework, and thus offers new opportunities for future development in this field.Availability and Implementation: The R package HiTC is available from the Bioconductor web site. A detailed vignette provides additional documentation and help for using the package.

DOI of Published Version

10.1093/bioinformatics/bts521

Source

Bioinformatics. 2012 Nov 1;28(21):2843-4. doi: 10.1093/bioinformatics/bts521

Journal/Book/Conference Title

Bioinformatics (Oxford, England)

Related Resources

Link to article in PubMed

PubMed ID

22923296