The Department of Surgery of the University of Massachusetts Medical School is an academic surgical program located in Worcester, Massachusetts. Clinical care encompasses the three main campuses of UMass Memorial Medical Center (University, Memorial, and Hahnemann), as well as affiliated hospitals. The department is committed to providing state-of-the-art surgical care to patients from throughout the New England region. In addition, this busy and growing department is actively involved with advancing the art of surgery, through research focused on new approaches to patient care, as well as surgical training and education of the next generation of surgeons. This collection showcases journal articles and other publications and presentations written by faculty and researchers of the Department of Surgery.

Follow


Publications from 2000

Link

Guidewire entrapment during deployment of the over-the-guidewire stainless steel Greenfield filter: a device design-related complication, Harry Schanzer and Andres Schanzer

Link

The hemodynamic and adrenergic effects of perioperative dexmedetomidine infusion after vascular surgery, Pekka Talke, Richard Chen, Brian Thomas, Anil Aggarwall, Alexandru Gottlieb, Per Thorborg, Stephen O. Heard, Albert Cheung, Stanley Lee Son, and Antero Kallio

Link

Experience with endoluminal colonic wall stents for the management of large bowel obstruction for benign and malignant disease, Wael Z. Tamim, Ali Ghallai, Timothy C. Counihan, Richard S. Swanson, Jay M. Colby, and W. Brian Sweeney

Link

Virus infection abrogates cd8(+) t cell deletion induced by donor-specific transfusion and anti-cd154 monoclonal antibody, Nicole A. Turgeon

Link

Viral infection abrogates CD8(+) T-cell deletion induced by costimulation blockade, Nicole A. Turgeon, Neal N. Iwakoshi, Nancy E. Phillips, William C. Meyers, Raymond M. Welsh, Dale L. Greiner, John P. Mordes, and Aldo A. Rossini

Link

The role of cell cycle regulatory protein, cyclin D1, in the progression of thyroid cancer, Songtao Wang, Ricardo V. Lloyd, Michael J. Hutzler, Marjorie Safran, Nilima A. Patwardhan, and Ashraf Khan

Publications from 1999

Link

Liposomal prostaglandin E1 (TLC C-53) in acute respiratory distress syndrome: a controlled, randomized, double-blind, multicenter clinical trial. TLC C-53 ARDS Study Group, Edward Abraham, Robert Baughman, Eugene Fletcher, Stephen O. Heard, James Lamberti, Howard Levy, Loren Nelson, Mark Rumbak, Jay Steingrub, James Taylor, Youn C. Park, Jeri Matera Hynds, and Jeffrey Freitag

Link

Oestrogen receptor (ER)-alpha and ER-beta isoforms in normal endometrial and endometriosis-derived stromal cells, Alfred W. Brandenberger, Dan I. Lebovic, Meng Kian Tee, Isabelle P. Ryan, Jennifer F. Tseng, Robert B. Jaffe, and Robert N. Taylor

Link

Bone SPECT of the spine: a comparison of attenuation correction techniques, James A. Case, Robert Licho, Michael A. King, and John P. Weaver

Link

A comparison of two antimicrobial-impregnated central venous catheters. Catheter Study Group, Rabih O. Darouiche, Issam I. Raad, Stephen O. Heard, John I. Thornby, Olivier C. Wenker, Andrea Gabrielli, Johannes Berg, Nancy Khardori, Hend Hanna, Ray Hachem, Richard L. Harris, and Glen Mayhall

Link

The influence of liposome-encapsulated prostaglandin E1 on hydrogen peroxide concentrations in the exhaled breath of patients with the acute respiratory distress syndrome, Stephen O. Heard, Karen J. Longtine, Ildiko Toth, Juan Carlos Puyana, Bruce Potenza, and Nicholas A. Smyrnios

Link

Expression of human estrogen receptor-alpha and -beta, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells, Kin-Mang Lau, Samuel C. Mok, and Shuk-Mei Ho

Link

Effects of cadmium on metallothionein-I and metallothionein-II mRNA expression in rat ventral, lateral, and dorsal prostatic lobes: quantification by competitive RT-PCR, Kai-Fai Lee, Kin-Mang Lau, and Shuk-Mei Ho

Link

The effects of aspirin and hypothermia on platelet function in vivo, Alan D. Michelson, Marc R. Barnard, Shukri F. Khuri, Michael J. Rohrer, Hollace Macgregor, and C. Robert Valeri

Link

Chronic venous insufficiency is associated with increased platelet and monocyte activation and aggregation, Craig C. Powell, Michael J. Rohrer, Marc R. Barnard, Brian D. Peyton, Mark I. Furman, and Alan D. Michelson

Link

Bronchopulmonary segmental lavage with Surfaxin (KL(4)-surfactant) for acute respiratory distress syndrome, Thomas E. Wiswell, Robert M. Smith, Laurence B. Katz, Lisa Mastroianni, Davies Y. Wong, David Willms, Stephen O. Heard, Mark M. Wilson, R. Duncan Hite, Antonio Anzueto, Susan D. Revak, and Charles G. Cochrane

Publications from 1998

Link

Estrogen receptor-alpha is developmentally regulated during osteoblast differentiation and contributes to selective responsiveness of gene expression, Peter V. N. Bodine, Ruth A. Henderson, Jack Green, Michael A. Aronow, Thomas A. Owen, Gary S. Stein, Jane B. Lian, and Barry S. Komm

Link

Partial liquid ventilation with perfluorocarbon in the treatment of rats with lethal pneumococcal pneumonia, Eric W. Dickson, Stephen O. Heard, Benson Chu, Armando E. Fraire, Angela B. Brueggemann, and Gary V. Doern

Link

Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease, Mark I. Furman, Stephen E. Benoit, Marc R. Barnard, C. Robert Valeri, Marie L. Borbone, Richard C. Becker, Herbert B. Hechtman, and Alan D. Michelson

Link

Effect of prophylactic administration of recombinant human granulocyte colony-stimulating factor (filgrastim) on the frequency of nosocomial infections in patients with acute traumatic brain injury or cerebral hemorrhage. The Filgrastim Study Group, Stephen O. Heard, Mitchell P. Fink, Richard L. Gamelli, Joseph S. Solomkin, Manjari Joshi, Arthur L. Trask, Timothy C. Fabian, Leonard D. Hudson, Kevin B. Gerold, and Eileen D. Logan

Link

Influence of triple-lumen central venous catheters coated with chlorhexidine and silver sulfadiazine on the incidence of catheter-related bacteremia, Stephen O. Heard, Manisha Wagle, Elamana Vijayakumar, Susan McLean, Angela Brueggemann, Lena M. Napolitano, L. Paul Edwards, Frank M. O'Connell, Juan Carlos Puyana, and Gary V. Doern

Link

Rat estrogen receptor-alpha and -beta, and progesterone receptor mRNA expression in various prostatic lobes and microdissected normal and dysplastic epithelial tissues of the Noble rats, Kin-Mang Lau, Irwin Leav, and Shuk-Mei Ho

Link

Adenosine A2a receptors increase arterial endothelial cell nitric oxide, Jian-ming Li, Richard A. Fenton, H. Brownell Wheeler, Craig C. Powell, Brian D. Peyton, Bruce S. Cutler, and James G. Dobson Jr.

Link

Patients with venous stasis ulceration have increased monocyte-platelet aggregation, Brian D. Peyton, Michael J. Rohrer, Mark I. Furman, Marc R. Barnard, Louis J. Rodino, Stephen E. Benoit, Herbert B. Hechtman, C. Robert Valeri, and Alan D. Michelson

Link

Stereotactic core needle biopsy of nonpalpable breast lesions: initial experience with a promising technique, Hani M. Seoudi, Johannes Mortier, Richard M. Basile, and Eugene L. Curletti

Link

Neoadjuvant chemoradiotherapy for esophageal cancer: is it worthwhile, Wael Z. Tamim, Robert S. Davidson, Robert M. Quinlan, Michael A. O'Shea, Richard K. Orr, and Richard S. Swanson

Link

Laparoscopic surgery and the systemic immune response, Frank J. Vittimberga Jr., David P. Foley, William C. Meyers, and Mark P. Callery

Publications from 1997

PDF

TrkA expression decreases the in vivo aggressiveness of C6 glioma cells, Mahesh B. Lachyankar, Alonzo H. Ross, N. Scott Litofsky, Peter J. Condon, Peter J. Quesenberry, and Lawrence D. Recht

Link

A comparison of GABAC and rho subunit receptors from the white perch retina, H. Qian, G. Hyatt, Andres Schanzer, R. Hazra, A. S. Hackam, G. R. Cutting, and John E. Dowling

Link

Angiogenesis and macrophage activation in endometriosis, Robert N. Taylor, Isabella P. Ryan, Ellen S. Moore, Daniella Hornung, Jan L. Shifren, and Jennifer F. Tseng

Link

Surgical management of primary cutaneous melanomas of the hands and feet, Jennifer F. Tseng, Kenneth K. Tanabe, Michelle A. Gadd, A. Benedict Cosimi, Ronald A. Malt, Frank G. Halulska, Martin C. Mihm Jr., Arthur J. Sober, and Wiley W. Souba

Link

The 1996 Bigelow Award of the Boston Surgical Society: Henry Jacob Bigelow and David C. Sabiston, Jr, H. Brownell Wheeler

Publications from 1996

Link

In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function, Alan D. Michelson, Marc R. Barnard, Herbert B. Hechtman, Hollace Macgregor, Raymond J. Connolly, Joseph Loscalzo, and C. Robert Valeri

Link

Blunt traumatic injury of the thoracic aorta following commercial airline crashes, A. Thomas Pezzella

Link

Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosis, Jan L. Shifren, Jennifer F. Tseng, Charles J. Zaloudek, Isabelle P. Ryan, Y. Gloria Meng, Napoleone Ferrara, Robert B. Jaffe, and Robert N. Taylor

Link

Interleukin-6 secretion in vitro is up-regulated in ectopic and eutopic endometrial stromal cells from women with endometriosis, Jennifer F. Tseng, Isabella P. Ryan, T. D. Milam, J. T. Murai, E. D. Schriock, D. V. Landers, and Robert N. Taylor

Link

Middle fossa cyst presenting as a delayed complication of temporal lobectomy: case report, John P. Weaver, Catherine Phillips, Sandra L. Horowitz, and Sheldon Benjamin

Publications from 1995

Link

Adenosine enhances nitric oxide production by vascular endothelial cells, Jian-ming Li, Richard A. Fenton, Bruce S. Cutler, and James G. Dobson Jr.

Link

Should we treat localized prostate cancer? An opinion, Mani Menon, B. G. Parulkar, and Stephen P. Baker

Link

Introduction to the reports from Vietnam, A. Thomas Pezzella

Link

Inhibition of superantigen-induced T cell proliferation and monocyte IL-1 beta, TNF-alpha, and IL-6 production by acute ethanol treatment, Gyongyi Szabo, Pranoti Mandrekar, and Donna Catalano

Publications from 1994

Link

Differential effects of warfarin on mRNA levels of developmentally regulated vitamin K dependent proteins, osteocalcin, and matrix GLA protein in vitro, Leesa M. Barone, Michael A. Aronow, Melissa S. Tassinari, Donna Conlon, Ernesto Canalis, Gary S. Stein, and Jane B. Lian

Link

TGF beta 1 prevents the down-regulation of type I procollagen, fibronectin, and TGF beta 1 gene expression associated with 3T3-L1 pre-adipocyte differentiation, Rita Bortell, Thomas A. Owen, Ronald A. Ignotz, Gary S. Stein, and Janet L. Stein

Link

TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype, Ellen C. Breen, Ronald A. Ignotz, Laura R. McCabe, Janet L. Stein, Gary S. Stein, and Jane B. Lian

PDF

Treatment of severe pneumonia in hospitalized patients: results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin. The Severe Pneumonia Study Group, Mitchell P. Fink, David R. Snydman, Michael S. Niederman, Kenneth V. Leeper Jr., Royce H. Johnson, Stephen O. Heard, Richard G. Wunderink, John W. Caldwell, Jerome J. Schentag, and Ghodrat A. Siami

Link

The role of protein kinase C in lipopolysaccharide-induced myocardial depression in guinea pigs, Stephen O. Heard, Ildiko E. Toth, Michael W. Perkins, and Jack L. Leonard

PDF

Neutrophil cathepsin G modulates the platelet surface expression of the glycoprotein (GP) Ib-IX complex by proteolysis of the von Willebrand factor binding site on GPIb alpha and by a cytoskeletal-mediated redistribution of the remainder of the complex, Charles A. LaRosa, Michael J. Rohrer, Stephen E. Benoit, Marc R. Barnard, and Alan D. Michelson

PDF

The activation-induced decrease in the platelet surface expression of the glycoprotein Ib-IX complex is reversible, Alan D. Michelson, Stephen E. Benoit, Michael H. Kroll, Jian-ming Li, Michael J. Rohrer, Anita S. Kestin, and Marc R. Barnard

Link

Dibutyryl-cAMP modulation of receptor expression and antigen presentation capacity in monocyte subpopulations, Gyongyi Szabo, Karen Kodys, and Carol L. Miller-Graziano

Link

Acute ethanol consumption synergizes with trauma to increase monocyte tumor necrosis factor alpha production late postinjury, Gyongyi Szabo, Pranoti Mandrekar, Bikash K. Verma, Ann Isaac, and Donna Catalano

Link

Regulatory potential of ethanol and retinoic acid on human monocyte functions, Gyongyi Szabo, Maria Puppolo, Bikash K. Verma, and Donna Catalano

Link

Subarachnoid hemorrhage: an update of pathogenesis, diagnosis and management, John P. Weaver and Marc Fisher

Publications from 1993

Link

Position and orientation-selective silencer in protein-coding sequences of the rat osteocalcin gene, Baruch Frenkel, Jolanda Mijnes, Michael A. Aronow, Gerard Zambetti, Chaitali Banerjee, Janet L. Stein, Jane B. Lian, and Gary S. Stein

Link

Selective inhibition of antigen-specific T lymphocyte proliferation by acute ethanol exposure: the role of impaired monocyte antigen presentation capacity and mediator production, Gyongyi Szabo, Bikash K. Verma, and Donna Catalano

Link

Down-regulation of tumor necrosis factor alpha activity by acute ethanol treatment in human peripheral blood monocytes, Bikash K. Verma, Miklos C. Fogarasi, and Gyongyi Szabo

Publications from 1992

Link

Intracranial metastatic adenoid cystic carcinoma: presumed hematogenous spread from a primary tumor in the parotid gland, Nicholas D. Gelber, Ronald L. Ragland, John R. Knorr, Thomas W. Smith, and Bernard B. Stone

Link

Analgesic effect of intraarticular bupivacaine or morphine after arthroscopic knee surgery: a randomized, prospective, double-blind study, Stephen O. Heard, W. Thomas Edwards, Dudley Ferrari, Deborah Hanna, Patricia D. Wong, Astrid Liland, and Marcelle M. Willock

Link

Clinical review 32: Calcium oxalate nephrolithiasis, Mani Menon and Hari Koul

PDF

Left ventricular systolic and diastolic dysfunction after infusion of tumor necrosis factor-alpha in conscious dogs, Francis D. Pagani, Lauren S. Baker, Charles Hsi, Mark A. Knox, Mitchell P. Fink, and Marc S. Visner

Link

Transatrial closure of postinfarction ventricular septal defect, A. Thomas Pezzella

Link

Sonography of hypertrophic pyloric stenosis: frequency and cause of nonuniform echogenicity of the thickened pyloric muscle, Melissa R. Spevak, Jonathan M. Ahmadjian, Paul K. Kleinman, Gisela Henriquez, Michael P. Hirsh, and Ian T. Cohen

Link

Induction of transforming growth factor-beta and prostaglandin E2 production by ethanol in human monocytes, Gyongyi Szabo, Bikash K. Verma, Miklos C. Fogarasi, and Donna Catalano

Publications from 1991

Link

Gastric tonometry in healthy volunteers: effect of ranitidine on calculated intramural pH, Stephen O. Heard, Cathleen M. Helsmoortel, Joel C. Kent, Albert Shahnarian, and Mitchell P. Fink

Link

Role of elevated monocyte transforming growth factor beta (TGF beta) production in posttrauma immunosuppression, Carol L. Miller-Graziano, Gyongyi Szabo, Katherine Griffey, Bela Mehta, Karen Kodys, and Donna Catalano

Link

Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: dependency upon basal levels of gene expression, duration of exposure, and bone matrix competency in normal rat osteoblast cultures, Thomas A. Owen, Michael A. Aronow, Leesa M. Barone, B. Bettencourt, Gary S. Stein, and Jane B. Lian

Link

Influence of dexamethasone on the vitamin D-mediated regulation of osteocalcin gene expression, Grace Schepmoes, Ellen C. Breen, Thomas A. Owen, Michael A. Aronow, Gary S. Stein, and Jane B. Lian

Link

Elevated monocyte interleukin-6 (IL-6) production in immunosppressed trauma patients. II. Downregulation by IL-4, Gyongyi Szabo, Karen Kodys, and Carol L. Miller-Graziano

Link

Elevated monocyte interleukin-6 (IL-6) production in immunosuppressed trauma patients. I. Role of Fc gamma RI cross-linking stimulation, Gyongyi Szabo, Karen Kodys, and Carol L. Miller-Graziano

Publications from 1990

Link

Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells, Michael A. Aronow, Louis C. Gerstenfeld, Thomas A. Owen, Melissa S. Tassinari, Gary S. Stein, and Jane B. Lian

Link

The efficacy of an oscillating bed in the prevention of lower respiratory tract infection in critically ill victims of blunt trauma. A prospective study, Mitchell P. Fink, Cathleen M. Heismoortel, Keith L. Stein, Patrick C. Lee, and Stephen M. Cohn

Link

Aberrations in post-trauma monocyte (MO) subpopulation: role in septic shock syndrome, Carol L. Miller-Graziano, Gyongyi Szabo, Karen Kodys, and Katherine Griffey

Link

Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix, Thomas A. Owen, Michael A. Aronow, Victoria Shalhoub, Leesa M. Barone, Laurens G. Wilming, Melissa S. Tassinari, Mary Beth Kennedy, Shirwin M. Pockwinse, Jane B. Lian, and Gary S. Stein

Link

Induction and regulation of monocyte procoagulant activity, Gyongyi Szabo and Carol L. Miller-Graziano

Link

Antigen presentation by the CD4 positive monocyte subset, Gyongyi Szabo, Carol L. Miller-Graziano, and Karen Kodys

Link

Differential tumor necrosis factor production by human monocyte subsets, Gyongyi Szabo, Carol L. Miller-Graziano, Jia-Yan Wu, Thomas K. Takayama, and Karen Kodys

Link

Elevated tumor necrosis factor alpha production concomitant to elevated prostaglandin E2 production by trauma patients' monocytes, Thomas K. Takayama, Carol L. Miller-Graziano, and Gyongyi Szabo

Publications from 1989

Link

Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit, Jyrki Heino, Ronald A. Ignotz, Martin E. Hemler, Carol Crouse, and Joan Massague

Link

Regulation of cell adhesion receptors by transforming growth factor-beta. Regulation of vitronectin receptor and LFA-1, Ronald A. Ignotz, Jyrki Heino, and Joan Massague

Link

Osteocalcin: characterization and regulated expression of the rat gene, Jane B. Lian, Gary S. Stein, C. Stewart, E. Puchacz, S. Mackowiak, Michael A. Aronow, M. Von Deck, and Victoria Shalhoub

Link

The onset and progression of osteoblast differentiation is functionally related to cellular proliferation, Gary S. Stein, Jane B. Lian, Louis C. Gerstenfeld, Victoria Shalhoub, Michael A. Aronow, Thomas A. Owen, and Elizabeth R. Markose

Link

Erroneous measurement of intracranial pressure caused by simultaneous ventricular drainage: a hydrodynamic model study, H. A. Wilkinson, Jorge L. Yarzebski, E. C. Wilkinson, and Frederick A. Anderson Jr.

Publications from 1988

Link

Mechanisms of altered monocyte prostaglandin E2 production in severely injured patients, Carol L. Miller-Graziano, Mitchell P. Fink, Jia-Yan Wu, Gyongyi Szabo, and Karen Kodys

Publications from 1986

Link

In vivo survival of red blood cells processed by a bubble or membrane oxygenator during cardiopulmonary bypass surgery, Jack E. Ansell, Thomas J. Vandersalm, Wendy P. Stephenson, Irma O. Szymanski, and Lawrence Fournier

Link

Prediction of the development of sigmoid ischemia on the day of aortic operations. Indirect measurements of intramural pH in the colon, Richard G. Fiddian-Green, Patricia M. Amelin, John B. Herrmann, Elias J. Arous, Bruce S. Cutler, Michael Schiedler, H. Brownell Wheeler, and Stephen P. Baker

Publications from 1981

Link

Arteriovenous fistula masquerading as valvular heart disease, Nancy L. Cantelmo, Joseph S. Alpert, Bruce S. Cutler, Joel S. Neuschatz, Luis Romero, and Ira S. Ockene

Publications from 1980

Link

Origin of the left anterior descending coronary artery from the pulmonary artery: An unusual cause of angina in a middle-aged woman, Terence H. Pringle, Ira S. Ockene, John P. Howe, Bruce S. Cutler, and Thomas J. Vander Salm