Histone proteins in HeLa S3 cells are synthesized in a cell cycle stage specific manner
Department of Cell Biology
*Cell Cycle; Cell Nucleus; Cytarabine; Cytoplasm; Female; Hela Cells; Histones; Humans; Protein Biosynthesis; Transcription, Genetic
The synthesis of histone proteins in G1 and S phase HeLa S3 cells was examined by two-dimensional electrophoretic fractionation of nuclear and total cellular proteins. Newly synthesized histones were detected only in S phase cells. Histone messenger RNA sequences, as detected by hybridization with cloned human histone genes, were present in the cytoplasm of S phase but not G1 cells.
Science. 1982 Feb 5;215(4533):683-5.
Science (New York, N.Y.)
Marashi F, Baumbach LL, Rickles R, Sierra F, Stein JL, Stein GS. (1982). Histone proteins in HeLa S3 cells are synthesized in a cell cycle stage specific manner. Stein, Stein, Lian, vanWijnen Lab Publications. Retrieved from https://escholarship.umassmed.edu/stein/161