T.H. Chan School of Medicine Student Publications

Title

Topical 5% 5-fluorouracil versus procedural modalities for squamous cell carcinoma in situ and superficial basal cell carcinoma: A retrospective cohort analysis

Student Author(s)

Holly Neale

UMMS Affiliation

Department of Dermatology; Department of Population and Quantitative Health Sciences; School of Medicine

Publication Date

2021-08-31

Document Type

Article

Disciplines

Dermatology | Skin and Connective Tissue Diseases

Abstract

The topical chemotherapeutic agent 5-fluorouracil (5-FU) is commonly used to treat squamous cell carcinoma in situ (SCCIS) and superficial basal cell carcinoma (sBCC). Additional investigation is needed to understand whether topical 5-FU, under real-world conditions, has comparable treatment success to procedures for epidermally-limited keratinocyte carcinomas. Approval was obtained from the University of Massachusetts Medical School institutional review board to perform a retrospective chart review.

Keywords

carcinomas, 5-fluorouracil

DOI of Published Version

10.1016/j.jaad.2021.08.045

Source

Neale H, Michelon M, Jacob S, Pinkston M, Ukaegbu R, Zamor W, Morrison E, Deng A, Levin NA. Topical 5% 5-fluorouracil versus procedural modalities for squamous cell carcinoma in situ and superficial basal cell carcinoma: A retrospective cohort analysis. J Am Acad Dermatol. 2021 Aug 31:S0190-9622(21)02390-2. doi: 10.1016/j.jaad.2021.08.045. Epub ahead of print. PMID: 34478783.

Journal/Book/Conference Title

Journal of the American Academy of Dermatology

Related Resources

View article in PubMed

PubMed ID

34478783

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