Two-way traffic: centrosomes and the cell cycle
Department of Cell Biology
Animals; Cell Cycle; Centrosome; Microsurgery; Signal Transduction
The well recognized activities of the mammalian centrosome--microtubule nucleation, duplication, and organization of the primary cilium--are under the control of the cell cycle. However, the centrosome is more than just a follower of the cell cycle; it can also be essential for the cell to transit G1 and enter S phase. How the centrosome influences G1 progression is a mystery.
DOI of Published Version
Nat Rev Mol Cell Biol. 2005 Sep;6(9):743-8. Link to article on publisher's site
Nature reviews. Molecular cell biology
Sluder G. (2005). Two-way traffic: centrosomes and the cell cycle. Sluder Lab Publications. https://doi.org/10.1038/nrm1712. Retrieved from https://escholarship.umassmed.edu/sluder/8