Centriole biogenesis: a tale of two pathways
Department of Cell Biology
Animals; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Centrioles; Drosophila; Embryo, Nonmammalian; Female; Humans; Models, Biological; Ovum
Two recent studies in Drosophila demonstrate that overexpression of proteins required for centriole duplication can not only induce centriole over-duplication in cells containing centrioles, but can also drive de novo centriole assembly in unfertilized eggs that initially lack centrioles. These studies offer a new perspective on the mechanisms that control centriole duplication.
DOI of Published Version
Nat Cell Biol. 2007 Jul;9(7):736-8. Link to article on publisher's site
Nature cell biology
Loncarek J, Sluder G, Khodjakov A. (2007). Centriole biogenesis: a tale of two pathways. Sluder Lab Publications. https://doi.org/10.1038/ncb0707-736. Retrieved from https://escholarship.umassmed.edu/sluder/4