Schafer Lab Publications
This collection showcases the journal articles and other publications authored by researchers in the Schafer Lab. The Schafer Lab at the University of Massachusetts Medical School was established in 2015, in the Department of Neurobiology.
Publications from 2020
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations, Patrick P. Lowe, Caroline Morel, Aditya Ambade, Arvin Iracheta-Vellve, Erica Kwiatkowski, Abhishek Satishchandran, Istvan Furi, Yeonhee Cho, Benedek Gyongyosi, Donna Catalano, Eric Lefebvre, Laurent Fischer, Star Seyedkazemi, Dorothy P. Schafer, and Gyongyi Szabo
Investigating Microglia-Vascular Interactions in the Developing and Adult Central Nervous System, Erica Mondo
A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature, Erica Mondo, Shannon C. Becker, Amanda G. Kautzman, Martina Schifferer, Christina E. Baer, Jiapei Chen, Eric J. Huang, Mikael Simons, and Dorothy P. Schafer
A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature [preprint], Erica Mondo, Shannon C. Becker, Amanda G. Kautzman, Martina Schifferer, Christina E. Baer, Jiapei Chen, Eric J. Huang, Mikael Simons, and Dorothy P. Schafer
Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease, Sebastian Werneburg, Jonathan Jung, Rejani B. Kunjamma, Seung-Kwon Ha, Nicholas J. Luciano, Cory M. Willis, Guangping Gao, Natalia P. Biscola, Leif A. Havton, Stephen J. Crocker, Brian Popko, Daniel S. Reich, and Dorothy P. Schafer
Publications from 2019
Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia, Sarah R. Anderson, Jianmin Zhang, Michael R. Steele, Cesar O. Romero, Amanda G. Kautzman, Dorothy P. Schafer, and Monica L. Vetter
Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors, Roey Baror, Bjorn Neumann, Michael Segel, Kevin J. Chalut, Stephen P.J. Fancy J, Dorothy P. Schafer, and Robin J.M. Franklin
Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling, Georgia Gunner, Kasey M. Johnson, Erica Mondo, Liwang Liu, Andrew R. Tapper, and Dorothy P. Schafer
Neuronal vulnerability and multilineage diversity in multiple sclerosis, Lucas Schirmer, Sebastian Werneburg, Dorothy P. Schafer, Arnold R. Kriegstein, and David H. Rowitch
Publications from 2018
Roles of microglia in nervous system development, plasticity, and disease, Beth Stevens and Dorothy P. Schafer
Publications from 2017
A microglia-cytokine axis to modulate synaptic connectivity and function, Sebastian Werneburg, Philip A. Feinberg, Kasey M. Johnson, and Dorothy P. Schafer
Publications from 2016
Microglia: Architects of the Developing Nervous System, Jeffrey L. Frost and Dorothy P. Schafer
Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression, Dorothy P. Schafer, Christopher T. Heller, Georgia Gunner, Molly Heller, Christopher Gordon, Timothy Hammond, Yochai Wolf, Steffen Jung, and Beth Stevens
Publications from 2015
Shank1 regulates excitatory synaptic transmission in mouse hippocampal parvalbumin-expressing inhibitory interneurons, Wenjie Mao, Takuya Watanabe, Sukhee Cho, Jeffrey L. Frost, Tina Truong, Xiaohu Zhao, and Kensuke Futai
Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages, Dorothy P. Schafer and Beth Stevens
Microglia Function in Central Nervous System Development and Plasticity, Dorothy P. Schafer and Beth Stevens