Competitive endogenous RNAs cannot alter microRNA function in vivo
RNA Therapeutics Institute; Department of Biochemistry and Molecular Pharmacology
Biochemistry, Biophysics, and Structural Biology | Cell and Developmental Biology | Genetics and Genomics | Therapeutics
In this issue of Molecular Cell, Denzler et al. (2014) report a quantitative study of microRNA function in adult mouse liver, suggesting that the natural abundance of miRNAs and their binding sites generally excludes the previously proposed regulation of miRNAs by competitive endogenous RNAs (ceRNAs).
DOI of Published Version
Mol Cell. 2014 Jun 5;54(5):711-3. doi: 10.1016/j.molcel.2014.05.023. Link to article on publisher's site
Broderick, Jennifer A. and Zamore, Phillip D., "Competitive endogenous RNAs cannot alter microRNA function in vivo" (2014). RNA Therapeutics Institute Publications. 30.