RNA Therapeutics Institute Publications

Title

Competitive endogenous RNAs cannot alter microRNA function in vivo

UMMS Affiliation

RNA Therapeutics Institute; Department of Biochemistry and Molecular Pharmacology

Publication Date

6-5-2014

Document Type

Article

Disciplines

Biochemistry, Biophysics, and Structural Biology | Cell and Developmental Biology | Genetics and Genomics | Therapeutics

Abstract

In this issue of Molecular Cell, Denzler et al. (2014) report a quantitative study of microRNA function in adult mouse liver, suggesting that the natural abundance of miRNAs and their binding sites generally excludes the previously proposed regulation of miRNAs by competitive endogenous RNAs (ceRNAs).

DOI of Published Version

10.1016/j.molcel.2014.05.023

Source

Mol Cell. 2014 Jun 5;54(5):711-3. doi: 10.1016/j.molcel.2014.05.023. Link to article on publisher's site

Journal/Book/Conference Title

Molecular cell

Related Resources

Link to Article in PubMed

PubMed ID

24905003

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