RNA Therapeutics Institute Publications

Title

A deeper look into translation initiation

UMMS Affiliation

RNA Therapeutics Institute; Department of Biochemistry and Molecular Pharmacology

Publication Date

10-23-2014

Document Type

Article

Disciplines

Biochemistry, Biophysics, and Structural Biology | Cell and Developmental Biology | Genetics and Genomics | Therapeutics

Abstract

Eukaryotic translation initiation requires coordinated assembly of a remarkable array of initiation factors onto the small ribosomal subunit to select an appropriate mRNA start codon. Studies from Erzberger et al. and Hussain et al. bring new insights into this mechanism by looking at early and late initiation intermediates.

DOI of Published Version

10.1016/j.cell.2014.10.005

Source

Cell. 2014 Oct 23;159(3):475-6. doi: 10.1016/j.cell.2014.10.005. Link to article on publisher's site

Journal/Book/Conference Title

Cell

Related Resources

Link to Article in PubMed

PubMed ID

25417100

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