A deeper look into translation initiation
RNA Therapeutics Institute; Department of Biochemistry and Molecular Pharmacology
Biochemistry, Biophysics, and Structural Biology | Cell and Developmental Biology | Genetics and Genomics | Therapeutics
Eukaryotic translation initiation requires coordinated assembly of a remarkable array of initiation factors onto the small ribosomal subunit to select an appropriate mRNA start codon. Studies from Erzberger et al. and Hussain et al. bring new insights into this mechanism by looking at early and late initiation intermediates.
DOI of Published Version
Cell. 2014 Oct 23;159(3):475-6. doi: 10.1016/j.cell.2014.10.005. Link to article on publisher's site
Korostelev AA. (2014). A deeper look into translation initiation. RNA Therapeutics Institute Publications. https://doi.org/10.1016/j.cell.2014.10.005. Retrieved from https://escholarship.umassmed.edu/rti_pubs/27