The Department of Medicine's Division of Rheumatology at the University of Massachusetts Medical School provides comprehensive care for patients with rheumatic diseases and is heavily involved in medical education and clinical research.This collection showcases journal articles and other publications and presentations written by faculty and researchers of the Division of Rheumatology.

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Publications from 2021

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Personal Experiences with Diagnostic Delay Among Axial Spondyloarthritis Patients: A Qualitative Study, Catherine E. Dube, Kate L. Lapane, Katarina A. Ferrucci, Ariel L. Beccia, Sara K. Khan, Esther Yi, Jonathan Kay, Kristine A. Kuhn, Alexis Ogdie, and Shao-Hsien Liu

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Association Between Baseline Anti-cyclic Citrullinated Peptide Antibodies and 6-Month Clinical Response Following Abatacept or TNF Inhibitor Treatment: A Real-World Analysis of Biologic-Experienced Patients with RA, Leslie R. Harrold, Joshua Bryson, Thomas Lehman, Joe Zhuo, Sheng Gao, Xue Han, Amy Schrader, Sabrina Rebello, Dimitrios A. Pappas, Tanya Sommers, and Joel M. Kremer

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Efficacy and safety of biosimilar CT-P17 versus reference adalimumab in subjects with rheumatoid arthritis: 24-week results from a randomized study, Jonathan Kay and Edward Keystone

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Primary care physician perspectives on screening for axial spondyloarthritis: A qualitative study, Kate L. Lapane, Divya Shridharmurthy, Sara Khan, Daniel Lindstrom, Ariel Beccia, Esther Yi, Jonathan Kay, Catherine E. Dube, and Shao-Hsien Liu

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cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE, Mona Motwani, Jason D. McGowan, Jennifer Antonovitch, Kevin MingJie Gao, Zhaozhao Jiang, Shrutie Sharma, Gretchen A. Baltus, Kevin M. Nickerson, Ann Marshak-Rothstein, and Katherine A. Fitzgerald

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Trabecular bone organoid model for studying the regulation of localized bone remodeling, Yongkuk Park, Eugene Cheong, Jun-Goo Kwak, Ryan Carpenter, Jae-Hyuck Shim, and Jungwoo Lee

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Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample, Divya Shridharmurthy, Danni Zhao, Kate L. Lapane, Jonggyu Baek, Jonathan Kay, and Shao-Hsien Liu

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Unmet Medical Needs in the Treatment and Management of Generalized Pustular Psoriasis Flares: Evidence from a Survey of Corrona Registry Dermatologists, Bruce Strober, Nirali Kotowsky, Rose Medeiros, Rachel H. Mackey, Leslie R. Harrold, Wendell C. Valdecantos, Mary Flack, Amanda K. Golembesky, and Mark Lebwohl

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Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial, Rene Westhovens and Jonathan Kay

Publications from 2020

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Interchangeability of Biosimilars: What Level of Clinical Evidence is Needed to Support the Interchangeability Designation in the United States, Daniel F. Alvarez, Gertjan Wolbink, Carol Cronenberger, John Orazem, and Jonathan Kay

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Body mass index and treatment survival in patients with RA starting treatment with TNFalpha-inhibitors: long-term follow-up in the real-life METEOR registry, Sytske Anne Bergstra, Cornelia F. Allaart, David Vega-Morales, Marieke De Buck, Elizabeth Murphy, Karen I. Salomon-Escoto, and Tom W. J. Huizinga

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MEKK2 mediates aberrant ERK activation in neurofibromatosis type I, Seoyeon Bok, Dong Yeon Shin, Alisha R. Yallowitz, Mark Eiseman, Michelle Cung, Ren Xu, Na Li, Jun Sun, Alfred L. Williams, John E. Scott, Bing Su, Jae-Hyuck Shim, and Matthew B. Greenblatt

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Disease activity and patient-reported outcomes in patients with rheumatoid arthritis and Sjogren's syndrome enrolled in a large observational US registry, Leslie R. Harrold, Ying Shan, Sabrina Rebello, Neil Kramer, Sean E. Connolly, Evo Alemao, Sheila Kelly, Joel M. Kremer, and Elliot D. Rosenstein

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Prevalence of Sjogren's syndrome associated with rheumatoid arthritis in the USA: an observational study from the Corrona registry, Leslie R. Harrold, Ying Shan, Sabrina Rebello, Neil Kramer, Sean E. Connolly, Evo Alemao, Sheila Kelly, Joel M. Kremer, and Elliot D. Rosenstein

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Examining Treatment Decision-Making Among Patients With Axial Spondyloarthritis: Insights From a Conjoint Analysis Survey, Woojin Joo, Christopher V. Almario, Mariko Ishimori, Yujin Park, Alma Jusufagic, Benjamin Noah, Lianne S. Gensler, R. Swamy Venuturupalli, Jonathan Kay, Michael H. Weisman, and Brennan M. R. Spiegel

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Changes in selected haematological parameters associated with JAK1/JAK2 inhibition observed in patients with rheumatoid arthritis treated with baricitinib, Jonathan Kay, Masayoshi Harigai, Josh Rancourt, Christina Dickson, Thomas Melby, Maher Issa, Inmaculada de la Torre, Yoshitaka Isaka, Anabela Cardoso, Chadi Saifan, Edward C. Keystone, Ronald F. van Vollenhoven, Jon T. Giles, Tom Wj. Huizinga, and Joel M. Kremer

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Osteoblast-Osteoclast Communication and Bone Homeostasis, Jung-Min Kim, Chujiao Lin, Zheni Stavre, Matthew B. Greenblatt, and Jae-Hyuck Shim

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Hydroxychloroquine and the risk of respiratory infections among RA patients, Joel M. Kremer, George W. Reed, Dimitrios A. Pappas, Leslie R. Harrold, Kevin J. Kane, Jeffrey Greenberg, and Kevin Winthrop

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Primary care physician perspectives on barriers to diagnosing axial Spondyloarthritis: a qualitative study, Kate L. Lapane, Sara Khan, Divya Shridharmurthy, Ariel Beccia, Catherine E. Dube, Esther Yi, Jonathan Kay, and Shao-Hsien Liu

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Physical activity and attitudes towards exercise in people with axial and peripheral spondyloarthritis, Shao-Hsien Liu, Divya Shridharmurthy, Kate L. Lapane, Catherine E. Dube, Ellen M. Gravallese, and Jonathan Kay

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Descriptive Comparisons of the Impact of Apremilast and Methotrexate Monotherapy in Oligoarticular Psoriatic Arthritis: the Corrona Psoriatic Arthritis/Spondyloarthritis Registry Results, Alexis Ogdie, Mei Liu, Meghan Glynn, Kelechi Emeanuru, Leslie R. Harrold, Sven Richter, Benoit Guerette, and Philip J. Mease

Publications from 2019

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Still Disease, Juhi Bhargava and Sreelakshmi Panginikkod

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Will savings from biosimilars offset increased costs related to dose escalation? A comparison of infliximab and golimumab for rheumatoid arthritis, Jeffrey R. Curtis, Fenglong Xie, Jonathan Kay, and Joel D. Kallich

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A Fifty-Two-Week, Randomized, Placebo-Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis, Atul Deodhar, Lianne S. Gensler, Jonathan Kay, Walter P. Maksymowych, Nigil Haroon, Robert Landewe, Martin Rudwaleit, Stephen Hall, Lars Bauer, Bengt Hoepken, Natasha de Peyrecave, Brian Kilgallen, and Desiree van der Heijde

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Long-term, Real-world Safety of Adalimumab in Rheumatoid Arthritis: Analysis of a Prospective US-Based Registry, Leslie R. Harrold, Jenny Griffith, Patrick Zueger, Heather J. Litman, Bernice Gershenson, Syed S. Islam, Christine J. Barr, Dianlin Guo, Jonathan Fay, and Jeffrey D. Greenberg

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The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis, Jung-Min Kim, Yeon-Suk Yang, Kwang Hwan Park, Hwanhee Oh, Matthew B. Greenblatt, and Jae-Hyuck Shim

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A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma, Anitha Krishnan, Andrew J. Kocab, David N. Zacks, Ann Marshak-Rothstein, and Meredith Gregory-Ksander

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Immunosuppressive treatment and the risk of diabetes in rheumatoid arthritis, Siri Lillegraven, Jeffrey D. Greenberg, George W. Reed, Katherine Saunders, Jeffrey R. Curtis, Leslie R. Harrold, Marc C. Hochberg, Dimitrios A. Pappas, Joel M. Kremer, and Daniel H. Solomon

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Physical activity and attitudes and perceptions towards physical activity in patients with spondyloarthritis: A systematic review, Shao-Hsien Liu, Stephen A. Morais, Kate L. Lapane, and Jonathan Kay

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Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models, Mona Motwani, Sudesh Pawaria, Jennifer Bernier, Stephanie Moses, Kate Henry, Terry Fang, Linda Burkly, Ann Marshak-Rothstein, and Katherine A. Fitzgerald

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Inclusion Body Myositis, Sreelakshmi Panginikkod and Rina Musa

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Uhthoff Phenomenon, Sreelakshmi Panginikkod and Lokesh A.. Rukmangadachar

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Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis, Yeon-Suk Yang, Jun Xie, Dan Wang, Jung-Min Kim, Phillip W. L. Tai, Ellen M. Gravallese, Guangping Gao, and Jae-Hyuck Shim

Publications from 2018

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Wrist Arthritis, Hossein Akhondi and Sreelakshmi Panginikkod

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Do Poor Prognostic Factors in Rheumatoid Arthritis Affect Treatment Choices and Outcomes? Analysis of a US Rheumatoid Arthritis Registry, Evo Alemao, Heather J. Litman, Sean E. Connolly, Sheila Kelly, Winnie Hua, Lisa Rosenblatt, Sabrina Rebello, Joel M. Kremer, and Leslie R. Harrold

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Safety and efficacy of subcutaneous tanezumab in patients with knee or hip osteoarthritis, Charles Birbara, Eugene J. Dabezies Jr, Aimee M. Burr, Robert J. Fountaine, Michael D. Smith, Mark T. Brown, Christine R. West, Rosalin H. Arends, and Kenneth M. Verburg

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Dermatomyositis And Polymyositis, Apoorva Cheeti and Sreelakshmi Panginikkod

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Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue, Laura T. Donlin, Ellen M. Gravallese, and Jennifer H. Anolik

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Therapeutic benefit of apremilast on enthesitis and dactylitis in patients with psoriatic arthritis: a pooled analysis of the PALACE 1-3 studies, Dafna D. Gladman, Arthur Kavanaugh, Juan J. Gomez-Reino, Jurgen Wollenhaupt, Maurizio Cutolo, Georg Schett, Eric Lespessailles, Benoit Guerette, Nikolay Delev, Lichen Teng, Christopher J. Edwards, Charles Birbara, and Philip J. Mease

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Breathing New Life into Interstitial Lung Disease in Rheumatoid Arthritis, Peter K. Gregersen and Ellen M. Gravallese

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The conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation, Shahrad Hakimian, Yevgeniy Popov, Abbas Rupawala, Karen I. Salomon-Escoto, Steven Hatch, and Randall Pellish

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Towards an arthritis flare-responsive drug delivery system, Nitin Joshi, Ellen M. Gravallese, Joerg Ermann, and Jeffrey M. Karp

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Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation, Purvi Mande, Bahar Zirak, Wei-Che Ko, Keyon Taravati, Karen L. Bride, Tia Bumpus Brodeur, April C. Deng, Karen A. Dresser, Zhaozhao Jiang, Rachel Ettinger, Katherine A. Fitzgerald, Michael D. Rosenblum, John E. Harris, and Ann Marshak-Rothstein

Publications from 2017

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STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice, Rebecca Baum, Shrutie Sharma, Jason M. Organ, Christopher Jakobs, Veit Hornung, David B. Burr, Ann Marshak-Rothstein, Katherine A. Fitzgerald, and Ellen M. Gravallese

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Tocilizumab combination therapy or monotherapy or methotrexate monotherapy in methotrexate-naive patients with early rheumatoid arthritis: 2-year clinical and radiographic results from the randomised, placebo-controlled FUNCTION trial, Gerd R. Burmester, William F. Rigby, Ronald F. van Vollenhoven, Jonathan Kay, Andrea Rubbert-Roth, Ricardo Blanco, Alysha Kadva, and Sophie Dimonaco

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Biosimilars: implications for rheumatoid arthritis therapy, Stanley Cohen and Jonathan Kay

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Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation, Josephine R. Giles, Adriana Turqueti Neves, Ann Marshak-Rothstein, and Mark J. Shlomchik

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Clinical trials of biosimilars should become more similar, Jonathan Kay and John D. Isaacs

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Synovium-Derived MicroRNAs Regulate Bone Pathways in Rheumatoid Arthritis, Yukiko Maeda, Nicholas H. Farina, Melissa M. Matzelle, Paul J. Fanning, Jane B. Lian, and Ellen M. Gravallese

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Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent, Sudesh Pawaria, Shrutie Sharma, Rebecca Baum, Kerstin Nundel, Patricia Busto, Ellen M. Gravallese, Katherine A. Fitzgerald, and Ann Marshak-Rothstein

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What Outcomes are Important for Gout Patients? In-Depth Qualitative Research into the Gout Patient Experience to Determine Optimal Endpoints for Evaluating Therapeutic Interventions, Sophi Tatlock, Katja Rudell, Charlotte Panter, Rob Arbuckle, Leslie R. Harrold, William J. Taylor, and Tara Symonds

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c-Jun N-terminal kinases (JNKs) are critical mediators of osteoblast activity in vivo, Ren Xu, Chao Zhang, Dong Yeon Shin, Jung-Min Kim, Sarfaraz Lalani, Na Li, Yeon-Suk Yang, Yifang Liu, Mark Eiseman, Roger J. Davis, Jae-Hyuck Shim, and Matthew B. Greenblatt

Publications from 2016

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Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice, Rebecca Baum, Kerstin Nundel, Sudesh Pawaria, Shrutie Sharma, Patricia Busto, Katherine A. Fitzgerald, Ellen M. Gravallese, and Ann Marshak-Rothstein

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Agreement between Rheumatologist and Patient-reported Adherence to Methotrexate in a US Rheumatoid Arthritis Registry, Jeffrey R. Curtis, Aseem Bharat, Lang Chen, Jeffrey D. Greenberg, Leslie R. Harrold, Joel M. Kremer, Tanya Sommers, and Dimitrios Pappas

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The term 'non-radiographic axial spondyloarthritis' is much more important to classify than to diagnose patients with axial spondyloarthritis, Atul Deodhar, Vibeke Strand, Jonathan Kay, and Juergen Braun

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The changing landscape of biosimilars in rheumatology, Thomas Dorner, Vibeke Strand, Paul Cornes, Joao Goncalves, Laszlo Gulacsi, Jonathan Kay, Tore K. Kvien, Josef S. Smolen, Yoshiya Tanaka, and Gerd R. Burmester

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Brief Report: Development and Validation of a Semiautomated Method to Measure Erosion Volume in Inflammatory Arthritis by Computed Tomography Scanning, Jeffrey Duryea, Ruby Russell, Ellen M. Gravallese, Jonathan Kay, Roger Han, Bing Lu, and Daniel H. Solomon

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Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3), Christopher J. Edwards, Francisco J. Blanco, Jeffrey Crowley, Charles Birbara, Janusz Jaworski, Jacob Aelion, Randall M. Stevens, Adele Vessey, Xiaojiang Zhan, and Paul Bird

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Differential Expression of Hedgehog and Snail in Cutaneous Fibrosing Disorders: Implications for Targeted Inhibition, Amrita Goyal, Katy R. Linskey, Jonathan Kay, Lyn M. Duncan, and Rosalynn M. Nazarian

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Control of the innate immune response by the mevalonate pathway, Zhaozhao Jiang, Celia E. Foster, Annie S. Li, Xiaoman Zhang, Ruth M. Gavin, Sorcha D. Forde, Gail Germain, Susan B. Carpenter, Neal S. Silverman, Ellen M. Gravallese, Katherine A. Fitzgerald, Douglas T. Golenbock, and Donghai Wang

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Five-year Safety Data from 5 Clinical Trials of Subcutaneous Golimumab in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis, Jonathan Kay, Roy Fleischmann, Edward Keystone, Elizabeth C. Hsia, Benjamin Hsu, Yiying Zhou, Neil Goldstein, and Jurgen Braun

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Objectively Measured Physical Activity and Symptoms Change in Knee Osteoarthritis, Shao-Hsien Liu, Jeffrey B. Driban, Charles Eaton, Timothy McAlindon, Leslie R. Harrold, and Kate L. Lapane

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Inflammation in arthritis induces expression of BMP3, an inhibitor of bone formation, Melissa M. Matzelle, A. T. Shaw, Rebecca Baum, Yukiko Maeda Garrison, J. Li, S. Karmakar, Catherine A. Manning, N. C. Walsh, V. Rosen, and Ellen M. Gravallese

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RANK-Independent Osteoclast Formation and Bone Erosion in Inflammatory Arthritis, William O'Brien, Brian M. Fissel, Yukiko Maeda Garrison, Jing Yan, Xianpeng Ge, Ellen M. Gravallese, Antonios O. Aliprantis, and Julia F. Charles

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Endothelial-specific inhibition of NF-kappaB enhances functional haematopoiesis, Michael G. Poulos, Pradeep Ramalingam, Michael C. Gutkin, Maria Kleppe, Michael Ginsberg, Michael J. P. Crowley, Olivier Elemento, Ross L. Levine, Shahin Rafii, Jan Kitajewski, Matthew B. Greenblatt, Jae-Hyuck Shim, and Jason M. Butler

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Imaging for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome, Steven Schaub, Hartley M. Sirkis, and Jonathan Kay

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Mediators of inflammation and bone remodeling in rheumatic disease, Anita T. Shaw and Ellen M. Gravallese

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IL-17A deficiency promotes periosteal bone formation in a model of inflammatory arthritis, Anita T. Shaw, Yukiko Maeda, and Ellen M. Gravallese

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Differential Effects of Inflammation on Bone and Response to Biologics in Rheumatoid Arthritis and Spondyloarthritis, Zheni Stavre, Katherine S. Upchurch, Jonathan Kay, and Ellen M. Gravallese

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Gadolinium-Induced Fibrosis, Derrick J. Todd and Jonathan Kay

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The unmet need in rheumatology: reports from the Targeted Therapies meeting 2016, Kevin Winthrop and Jonathan Kay

Publications from 2015

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Bone as a Target Organ in Rheumatic Disease: Impact on Osteoclasts and Osteoblasts, Rebecca Baum and Ellen M. Gravallese

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Cutting Edge: AIM2 and Endosomal TLRs Differentially Regulate Arthritis and Autoantibody Production in DNase II-Deficient Mice, Rebecca Baum, Shrutie Sharma, Susan Carpenter, Quan-Zhen Li, Patricia Busto, Katherine A. Fitzgerald, Ann Marshak-Rothstein, and Ellen M. Gravallese

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Role of vascular channels as a novel mechanism for subchondral bone damage at cruciate ligament entheses in osteoarthritis and inflammatory arthritis, D. A. Binks, Ellen M. Gravallese, D. Bergin, R. J. Hodgson, A. L. Tan, Melissa M. Matzelle, D. McGonagle, and A. Radjenovic

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Detection of IgG4-Specific Autoantibodies in Rheumatoid Arthritis Serum Samples, Azra Borogovac, Youmna Lahoud, Janice Weaver, Sheldon M. Cooper, Mercedes Rincon, Jonathan Kay, and Ellen M. Gravallese

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Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial, Gerd R. Burmester, William F. Rigby, Ronald F. van Vollenhoven, Jonathan Kay, Andrea Rubbert-Roth, Ariella Kelman, Sophie Dimonaco, and Nina Mitchell

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Biosimilars in rheumatology: what the clinician should know, Gilberto Castaneda-Hernandez, Rodrigo Gonzalez-Ramirez, Jonathan Kay, and Morton A. Scheinberg

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Biosimilars in rheumatology: current perspectives and lessons learnt, Thomas Dorner and Jonathan Kay

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Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model, Pierre Duffau, Hanni Menn-Josephy, Carla M. Cuda, Salina Dominguez, Tamar R. Aprahamian, Amanda A. Watkins, Kei Yasuda, Paul Monach, Robert Lafyatis, Lisa M. Rice, G. Kenneth Haines 3rd., Ellen M. Gravallese, Rebecca Baum, Christophe Richez, Harris Perlman, Ramon G. Bonegio, and Ian R. Rifkin

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Effectiveness of Rituximab for the Treatment of Rheumatoid Arthritis in Patients with Prior Exposure to Anti-TNF: Results from the CORRONA Registry, Leslie R. Harrold, George W. Reed, Ashwini Shewade, Robert P. Magner, Katherine Saunders, Ani John, Joel M. Kremer, and Jeffrey D. Greenberg

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Golimumab 3-year safety update: an analysis of pooled data from the long-term extensions of randomised, double-blind, placebo-controlled trials conducted in patients with rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis, Jonathan Kay, Roy Fleischmann, Edward Keystone, Elizabeth C. Hsia, Benjamin Hsu, Michael Mack, Neil Goldstein, Jurgen Braun, and Arthur Kavanaugh

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Efficacy and safety results from a Phase 3, randomized, placebo-controlled trial of subcutaneous golimumab in Chinese patients with active rheumatoid arthritis despite methotrexate therapy, Zhanguo Li, Fengchun Zhang, Jonathan Kay, Kaiyin Fei, Chenglong Han, Yanli Zhuang, Zhong Wu, and Elizabeth C. Hsia

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Membrane-bound and soluble Fas ligands have opposite functions in photoreceptor cell death following separation from the retinal pigment epithelium, H. Matsumoto, Y. Murakami, K. Kataoka, S. Notomi, D. Mantopoulos, G. Trichonas, J. W. Miller, M. S. Gregory, B R. Ksander, Ann Marshak-Rothstein, and D. G. Vavvas

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Overcoming adherence issues and other barriers to optimal care in gout, Navine Nasser-Ghodsi and Leslie R. Harrold

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Quality indicators in rheumatoid arthritis: results from the METEOR database, Victoria Navarro-Compan, Josef S. Smolen, Tom Huizinga, Robert Landewe, Gianfranco Ferraccioli, Jose A.P. da Silva, Robert J. Moots, Jonathan Kay, and Desiree van der Heijde

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An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual, Sudesh Pawaria, Krishna L. Moody, Patricia Busto, Kerstin Nundel, Rebecca Baum, Shrutie Sharma, Ellen M. Gravallese, Katherine A. Fitzgerald, and Ann Marshak-Rothstein

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Suppression of systemic autoimmunity by the innate immune adaptor STING, Shrutie Sharma, Allison M. Campbell, Jennie Chan, Stefan A. Schattgen, Gregory M. Orlowski, Ribhu Nayar, Annie H. Huyler, Kerstin Nundel, Chandra Mohan, Leslie J. Berg, Mark J. Shlomchik, Ann Marshak-Rothstein, and Katherine A. Fitzgerald

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Golimumab in patients with active rheumatoid arthritis after treatment with tumor necrosis factor inverted question mark inhibitors: findings with up to five years of treatment in the multicenter, randomized, double-blind, placebo-controlled, phase 3 GO-AFTER study, Josef S. Smolen, Jonathan Kay, Mittie Doyle, Robert Landewe, Eric L. Matteson, Norman Gaylis, Jurgen Wollenhaupt, Frederick T. Murphy, Stephen Xu, Yiying Zhou, and Elizabeth C. Hsia

Publications from 2014

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Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy, Herbert S. B. Baraf, Robert A. Yood, Faith D. Ottery, John S. Sundy, and Michael A. Becker

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Impact of inflammation on the osteoblast in rheumatic diseases, Rebecca Baum and Ellen M. Gravallese

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Nephrogenic systemic fibrosis is associated with hypophosphataemia: a case-control study, Elana J. Bernstein, Tamara Isakova, Mary E. Sullivan, Lori B. Chibnik, Myles Wolf, and Jonathan Kay

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Current status of nephrogenic systemic fibrosis, L. Daftari Besheli, S. Aran, K. Shaqdan, Jonathan Kay, and H. Abujudeh

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Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA), Maxime Dougados, Martin Soubrier, Anna Antunez, Peter Balint, Alejandro Balsa, Maya H. Buch, Gustavo Casado, Jacqueline Detert, Bassel El-Zorkany, Paul Emery, Najia Hajjaj-Hassouni, Masayoshi Harigai, Shue-Fen Luo, Reka Kurucz, Gabriel Maciel, Emilio Martin Mola, Carlo Maurizio Montecucco, Iain McInnes, Helga Radner, Josef S. Smolen, Yeong-Wook Song, Harald Erwin Vonkeman, Kevin Winthrop, and Jonathan Kay

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Induction of bone loss in DBA/1J mice immunized with citrullinated autologous mouse type II collagen in the absence of adjuvant, Anand Dusad, Michael J. Duryee, Anita T. Shaw, Lynell W. Klassen, Daniel R. Anderson, Dong Wang, Ke Ren, Ellen M. Gravallese, James R. O'Dell, Ted R. Mikuls, and Geoffrey M. Thiele

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Clinical disease activity and acute phase reactant levels are discordant among patients with active rheumatoid arthritis: acute phase reactant levels contribute separately to predicting outcome at one year, Jonathan Kay, Olga Morgacheva, Susan P. Messing, Joel M. Kremer, Jeffrey D. Greenberg, George W. Reed, Ellen M. Gravallese, and Daniel E. Furst

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Ligation of TLR5 promotes myeloid cell infiltration and differentiation into mature osteoclasts in rheumatoid arthritis and experimental arthritis, Seung-Jae Kim, Zhenlong Chen, Nathan D. Chamberlain, Abdul B. Essani, Michael V. Volin, M. Asif Amin, Suncica Volkov, Ellen M. Gravallese, Shiva Arami, William Swedler, Nancy E. Lane, Anjali Mehta, Nadera Sweiss, and Shiva Shahrara

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Treatment of rheumatoid arthritis with marine and botanical oils: an 18-month, randomized, and double-blind trial, George W. Reed, Katherine Leung, Ronald G. Rossetti, Susan Van Buskirk, John T. Sharp, and Robert B. Zurier

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Gadolinium-based compounds induce NLRP3-dependent IL-1beta production and peritoneal inflammation, Christian Schmidt-Lauber, Lukas Bossaller, Hani H. Abujudeh, Gregory I. Vladimer, Anette Christ, Katherine A. Fitzgerald, Eicke Latz, Ellen M. Gravallese, Ann Marshak-Rothstein, and Jonathan Kay

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Sarilumab for the treatment of ankylosing spondylitis: results of a Phase II, randomised, double-blind, placebo-controlled study (ALIGN), Joachim Sieper, Jurgen Braun, Jonathan Kay, Salvatore Badalamenti, Allen R. Radin, Lixia Jiao, Stefano Fiore, Tanya Momtahen, George D. Yancopoulos, Neil Stahl, and Robert D. Inman

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Insights into the efficacy of golimumab plus methotrexate in patients with active rheumatoid arthritis who discontinued prior anti-tumour necrosis factor therapy: post-hoc analyses from the GO-AFTER study, Josef S. Smolen, Jonathan Kay, Eric L. Matteson, Robert Landewe, Elizabeth C. Hsia, Stephen Xu, Yiying Zhou, and Mittie K. Doyle