Assessment of liver fat in an obese patient population using noncontrast CT fat percent index
Department of Radiology
Investigative Techniques | Radiology
OBJECTIVE: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S).
METHODS: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI = [(65-patient HU)/65]x100, normal live r = 65 HU.
RESULTS: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r = -0.901), CTL-S (r = -0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P < .05).
CONCLUSION: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.
DOI of Published Version
Clin Imaging. 2014 May-Jun;38(3):259-64. doi: 10.1016/j.clinimag.2014.01.005. Epub 2014 Jan 17. Link to article on publisher's site
Jon, Ali F.; Cheema, Ahmad R.; Khan, Atif N.; Raptopoulos, Vassilios; Hauser, Thomas; Nasser, Imad; Welty, Francine K.; Karellas, Andrew; and Clouse, Melvin E., "Assessment of liver fat in an obese patient population using noncontrast CT fat percent index" (2014). Radiology Publications and Presentations. 77.