Development and testing of a single frequency terahertz imaging system for breast cancer detection
Authors
St Peter, BenjaminYngvesson, Sigfrid
Siqueira, Paul
Kelly, Patrick
Khan, Ashraf
Glick, Stephen J.
Karellas, Andrew
UMass Chan Affiliations
Department of RadiologyDocument Type
Journal ArticlePublication Date
2013-07-01Keywords
Bioimaging and Biomedical OpticsBiological and Chemical Physics
Diagnosis
Investigative Techniques
Medical Biophysics
Neoplasms
Radiology
Metadata
Show full item recordAbstract
The ability to discern malignant from benign tissue in excised human breast specimens in Breast Conservation Surgery (BCS) was evaluated using single frequency terahertz radiation. Terahertz (THz) images of the specimens in reflection mode were obtained by employing a gas laser source and mechanical scanning. The images were correlated with optical histological micrographs of the same specimens, and a mean discrimination of 73% was found for five out of six samples using Receiver Operating Characteristic (ROC) analysis. The system design and characterization is discussed in detail. The initial results are encouraging but further development of the technology and clinical evaluation is needed to evaluate its feasibility in the clinical environment.Source
IEEE J Biomed Health Inform. 2013 Jul;17(4):785-97. doi: 10.1109/JBHI.2013.2267351. Link to article on publisher's siteDOI
10.1109/JBHI.2013.2267351Permanent Link to this Item
http://hdl.handle.net/20.500.14038/48586PubMed ID
25055306Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1109/JBHI.2013.2267351