Flow Diverter Reconstruction of Internal Carotid Artery (Loop) Dissections with or without Associated Pseudoaneurysms
Division of Neurointerventional Radiology, Department of Radiology; New England Center for Stroke Research
Cardiovascular Diseases | Nervous System Diseases | Neurology | Neurosurgery | Radiology
OBJECTIVE: Endovascular treatment of cervical internal carotid artery (ICA) loop dissections in acute stroke interventions can be challenging. Flow diverters can effectively reconstruct vessel loops and treat the injured vessel and provide a safe conduit for intracranial catheterization.
METHODS: We retrospectively reviewed our neurointerventional database and identified all patients with ICA loop dissections treated with flow diverters in the acute setting between August 2016 and September 2020. Patient demographics, procedural data, imaging follow-up results, and clinical outcome information were collected.
RESULTS: Seven patients with a mean age of 62 years (range: 43-85 years) who underwent reconstruction of an ICA (loop) dissection with flow diverters were included. Four ICA dissections were treated with the Surpass Streamline flow diverter and 3 with the Pipeline embolization device. All cases were technically successful. All stroke cases achieved intracranial flow > /=thrombolysis in cerebral infarction 2B. Observed intracranial hemorrhages were all asymptomatic. All cases showed patent flow diverter(s) with or without (carotid) stent(s) on follow-up imaging. Semielectively treated patients did not show a change from baseline modified Rankin scale related to the procedure. Patients with acute stroke had a modified Rankin scale < /=2 in 4 of 5 cases (80%) at 3 months. Two patients died due to medical issues unrelated to the procedures. No patient showed new or recurrent symptoms.
CONCLUSION: Use of flow diverters, in some cases in conjunction with (carotid) stents, is an effective treatment option for cervical carotid artery (loop) dissections.
Carotid stent, Dissection, Flow diverter, Internal carotid artery, Pseudoaneurysm, Stroke
DOI of Published Version
Kühn AL, Singh J, Massari F, de Macedo Rodrigues K, Gounis MJ, Puri AS. Flow Diverter Reconstruction of Internal Carotid Artery (Loop) Dissections with or without Associated Pseudoaneurysms. World Neurosurg. 2022 Feb 22:S1878-8750(22)00220-0. doi: 10.1016/j.wneu.2022.02.073. Epub ahead of print. PMID: 35217230. Link to article on publisher's site
Kuhn AL, Singh J, Massari F, de Macedo Rodrigues K, Gounis MJ, Puri AS. (2022). Flow Diverter Reconstruction of Internal Carotid Artery (Loop) Dissections with or without Associated Pseudoaneurysms. Radiology Publications. https://doi.org/10.1016/j.wneu.2022.02.073. Retrieved from https://escholarship.umassmed.edu/radiology_pubs/699