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UMass Chan Affiliations
Department of RadiologyDocument Type
Journal ArticlePublication Date
2021-06-12Keywords
angiographycerebrovascular disease
intracranial aneurysm
intracranial atherosclerosis
optical coherence tomography
Cardiovascular Diseases
Nervous System Diseases
Radiology
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Show full item recordAbstract
Diagnosis of cerebrovascular disease includes vascular neuroimaging techniques such as computed tomography (CT) angiography, magnetic resonance (MR) angiography (with or without use of contrast agents) and catheter digital subtraction angiography (DSA). These techniques provide mostly information about the vessel lumen. Vessel wall imaging with MR seeks to characterize cerebrovascular pathology, but with resolution that is often insufficient for small lesions. Intravascular imaging techniques such as ultrasound and optical coherence tomography (OCT), used for over a decade in the peripheral circulation, is not amendable to routine deployment in the intracranial circulation due to vessel caliber and tortuosity. However, advances in OCT technology including the probe profile, stiffness and unique distal rotation solution, holds the promise for eventual translation of OCT into the clinical arena. As such, it is apropos to review this technology and present the rationale for utilization of OCT in the cerebrovasculature.Source
Anagnostakou V, Ughi GJ, Puri AS, Gounis MJ. Optical Coherence Tomography for Neurovascular Disorders. Neuroscience. 2021 Jun 12:S0306-4522(21)00300-6. doi: 10.1016/j.neuroscience.2021.06.008. Epub ahead of print. PMID: 34126186. Link to article on publisher's site
DOI
10.1016/j.neuroscience.2021.06.008Permanent Link to this Item
http://hdl.handle.net/20.500.14038/48545PubMed ID
34126186Related Resources
ae974a485f413a2113503eed53cd6c53
10.1016/j.neuroscience.2021.06.008