Department of Pediatrics, Division of Pediatric Neonatalogy; Department of Radiology
Maternal and Child Health | Pediatrics | Radiology
Very preterm infants are at risk for germinal matrix hemorrhage- intraventricular hemorrhage (GH-IVH). Severe GH-IVH may cause death or severe neurodevelopmental disability while mild GH-IVH is considered a static, non-progressive disease. This retrospective study aimed to determine if infants with no GH-IVH or mild GH-IVH on initial screening head ultrasound (HUS) advanced to severe GH-IVH. A total of 353 eligible infants with birth gestational age < /=32 0/7 weeks who received a HUS during hospitalization were identified. Of the 343 (97%) infants who had mild GH-IVH (grade II or less) on initial screening, only 4 (1.2%) progressed to severe (grade III or IV). Each of these infants required mechanical ventilation for at least 40 days. Therefore, premature infants who have no GH-IVH or mild GH-IVH on initial routine screening HUS without other risk factors may not require follow-up HUSs. Infants with prolonged mechanical ventilation may require further screening despite reassuring initial HUS findings.
head ultrasound, intraventricular hemorrhage, preterm birth
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DOI of Published Version
Daigneault J, White H, Dube A, Shi Q, Gauguet JM, Rhein L. Lack of Progression of Intraventricular Hemorrhage in Premature Infants: Implications for Head Ultrasound Screening. Glob Pediatr Health. 2021 May 19;8:2333794X211010729. doi: 10.1177/2333794X211010729. PMID: 34046517; PMCID: PMC8138291. Link to article on publisher's site
Global pediatric health
Daigneault J, White H, Dube A, Shi Q, Gauguet J, Rhein LM. (2021). Lack of Progression of Intraventricular Hemorrhage in Premature Infants: Implications for Head Ultrasound Screening. Radiology Publications. https://doi.org/10.1177/2333794X211010729. Retrieved from https://escholarship.umassmed.edu/radiology_pubs/621
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This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License