Imaging manifestations of immune-related adverse effects in checkpoint inhibitor therapies: A primer for the radiologist
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UMass Chan Affiliations
Department of RadiologyDocument Type
Journal ArticlePublication Date
2020-07-01
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Immune checkpoint inhibitors are monoclonal antibodies directed against cellular pathways on T-cells to treat different types of malignancies. This new therapy can cause immune-related adverse events that can involve almost any organ system. This article will review clinical presentations, molecular mechanisms and imaging manifestations of adverse events caused by checkpoint inhibitors and also illustrate the pseudoprogression tumor response pattern.Source
Furtado VF, Melamud K, Hassan K, Rohatgi S, Buch K. Imaging manifestations of immune-related adverse effects in checkpoint inhibitor therapies: A primer for the radiologist. Clin Imaging. 2020 Jul;63:35-49. doi: 10.1016/j.clinimag.2020.02.006. Epub 2020 Feb 22. PMID: 32120311. Link to article on publisher's site
DOI
10.1016/j.clinimag.2020.02.006Permanent Link to this Item
http://hdl.handle.net/20.500.14038/48492PubMed ID
32120311Related Resources
ae974a485f413a2113503eed53cd6c53
10.1016/j.clinimag.2020.02.006