Title

Association of Varus Knee Thrust During Walking With Worsening Western Ontario and McMaster Universities Osteoarthritis Index Knee Pain: A Prospective Cohort Study

UMMS Affiliation

Department of Radiology

Publication Date

2019-10-01

Document Type

Article

Disciplines

Musculoskeletal Diseases | Orthopedics | Radiology | Rheumatology

Abstract

OBJECTIVE: To investigate the 2-year association of varus knee thrust observed during walking to the odds of worsening Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) knee pain in older adults with or at risk of osteoarthritis (OA).

METHODS: Video recordings of self-paced walking trials of Multicenter Osteoarthritis Study participants were assessed for the presence of varus thrust at baseline. Knee pain was assessed using the WOMAC questionnaire at baseline and at 2 years. Logistic regression was used to estimate the odds of worsening knee pain (defined as either any increase in WOMAC score or as clinically important worsening), adjusting for age, sex, race, body mass index, clinic site, gait speed, and static knee alignment. Analyses were repeated, stratified by baseline radiographic OA status and among the subset of knees without baseline WOMAC pain.

RESULTS: A total of 1,623 participants contributed 3,204 knees. Varus thrust was observed in 31.5% of knees. Knees with varus thrust had 1.44 times (95% confidence interval [95% CI] 1.19-1.73) the odds of any worsening and 1.37 times (95% CI 1.11-1.69) the odds of clinically important worsening WOMAC pain compared to knees without thrust. Knees with thrust without baseline WOMAC pain had 2.01 times (95% CI 1.47-2.74) the odds of incident total pain.

CONCLUSION: Results indicate that varus thrust is a risk factor for worsening and incident knee pain. Targeting varus thrust through noninvasive therapies could prevent development or worsening of knee pain in older adults with or at risk for knee OA.

DOI of Published Version

10.1002/acr.23766

Source

Wink AE, Gross KD, Brown CA, Lewis CE, Torner J, Nevitt MC, Tolstykh I, Sharma L, Felson DT. Association of Varus Knee Thrust During Walking With Worsening Western Ontario and McMaster Universities Osteoarthritis Index Knee Pain: A Prospective Cohort Study. Arthritis Care Res (Hoboken). 2019 Oct;71(10):1353-1359. doi: 10.1002/acr.23766. Epub 2019 Aug 19. PMID: 30242985; PMCID: PMC6430708. Link to article on publisher's site

Journal/Book/Conference Title

Arthritis care and research

Related Resources

Link to Article in PubMed

PubMed ID

30242985

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