Introduction. Formation, growth, and rupture: the biology and physics of cerebral aneurysms
Department of Radiology, Division of Neuroimaging and Intervention; New England Center for Stroke Research
Cardiovascular Diseases | Nervous System Diseases | Neurology | Radiology | Surgery
his issue of Neurosurgical Focus addresses several of the important biological and genetic aspects of aneurysm formation. The reader will be exposed to the latest theories of aneurysm formation that invoke genetic predispositions and the role of inflammation and matrix metalloproteinases in the genesis of a cerebral aneurysm. Observational studies provide additional insight into the role of estrogen and other female sex steroids and tobacco use with respect to the evolution of multiple aneurysms.
DOI of Published Version
Neurosurg Focus. 2019 Jul 1;47(1):E1. doi: 10.3171/2019.4.FOCUS19333. Link to article on publisher's site
Prestigiacomo CJ, Gounis MJ, Gonzalez LF, Frosen J. (2019). Introduction. Formation, growth, and rupture: the biology and physics of cerebral aneurysms. Radiology Publications. https://doi.org/10.3171/2019.4.FOCUS19333. Retrieved from https://escholarship.umassmed.edu/radiology_pubs/490