Pipeline Embolization Device for Pericallosal Artery Aneurysms: A Retrospective Single Center Safety and Efficacy Study
Department of Radiology, Division of Neuroimaging and Intervention; New England Center for Stroke Research
Neurology | Radiology
BACKGROUND: Pericallosal artery aneurysm treatment may be challenging using traditional endovascular techniques.
OBJECTIVE: To demonstrate the feasibility, efficacy, and safety of endovascular treatment of pericallosal artery aneurysm using flow diverters.
METHODS: We performed a retrospective review of our institutional database from July 2013 through July 2016 and identified 7 subjects with a pericallosal artery aneurysm treated with the Pipeline embolization device (ev3 Neurovascular, Medtronic, Dublin, Ireland) and at least 1 follow-up angiogram. Technical feasibility, procedural complication, angiographic results, and clinical outcome were evaluated.
RESULTS: Placement of the Pipeline embolization device was successful in all cases without evidence of procedural complication. Five out of 7 subjects showed a complete aneurysm occlusion at 6- to 12-mo follow-up angiogram. The 2 subjects with persistent aneurysm filling showed decreased aneurysm sac volume on follow-up angiograms (96% and 60%). There was no evidence of in-implant stenosis or intimal hyperplasia. No thromboembolic or hemorrhagic complications were seen during the follow-up period. Only 1 patient had a transient change in Modified Rankin scale score from baseline as a result of different unrelated procedure.
CONCLUSION: Our preliminary results demonstrate feasibility of the use of flow diverter stent for treatment of aneurysms of the pericallosal artery with rate of aneurysm occlusion comparable to literature and without evidence of increased procedural or short-term morbidity. A long-term and larger cohort study is needed to validate our findings.
aneurysm, artery, flow diverter, pericallosal
DOI of Published Version
Oper Neurosurg (Hagerstown). 2017 May 17. doi: 10.1093/ons/opx111. Link to article on publisher's site
Operative neurosurgery (Hagerstown, Md.)
Rodrigues KD, Kuhn AL, Tamura T, Dabus G, Kan P, Marosfoi MG, Lozano JD, Perras M, Brooks C, Howk M, Hou SY, Rex DE, Massari F, Gounis MJ, Wakhloo AK, Puri AS. (2017). Pipeline Embolization Device for Pericallosal Artery Aneurysms: A Retrospective Single Center Safety and Efficacy Study. Radiology Publications. https://doi.org/10.1093/ons/opx111. Retrieved from https://escholarship.umassmed.edu/radiology_pubs/319