What we have learned: the impact of quality from a clinical trials perspective
Department of Radiation Oncology; Quality Assurance Review Center
Cancer Care Facilities; Clinical Protocols; Clinical Trials as Topic; Credentialing; Hodgkin Disease; Humans; Medical Informatics; National Cancer Institute (U.S.); *Process Assessment (Health Care); *Quality Assurance, Health Care; Radiation Oncology; Research Design; United States
Neoplasms | Oncology
In this review article, we address the radiation oncology process improvements in clinical trials and review how these changes improve the quality for the next generation of trials. In recent years, we have progressed from a time of limited data acquisition to the present in which we have real-time influence of clinical trials quality. This enables immediate availability of the important elements, including staging, eligibility, response, and outcome for all trial investigators. Modern informatics platforms are well designed for future adaptive clinical trials. We review what will be needed in the informatics architecture of current and future clinical trials.
DOI of Published Version
Semin Radiat Oncol. 2012 Jan;22(1):18-28. doi: 10.1016/j.semradonc.2011.09.004. Link to article on publisher's site
Seminars in radiation oncology
Fitzgerald, Thomas J., "What we have learned: the impact of quality from a clinical trials perspective" (2012). Radiation Oncology Publications and Presentations. 40.