Comparison of efficacy, safety, and cost of low-molecular-weight heparin with continuous-infusion unfractionated heparin for initiation of anticoagulation after mechanical prosthetic valve implantation
Department of Quantitative Health Sciences
Anticoagulants; Case-Control Studies; Female; *Heart Valve Prosthesis Implantation; Heparin; Heparin, Low-Molecular-Weight; Hospital Costs; Humans; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Safety; Warfarin
Biostatistics | Epidemiology | Health Services Research
We compared the efficacy, safety, and impact on postoperative hospital length of stay and inpatient hospital costs of low-molecular-weight heparin with that of unfractionated heparin as a "bridge" to achieving therapeutic levels of anticoagulation with warfarin in patients with newly implanted prosthetic heart valves. The patients who received low-molecular-weight heparin had a shorter length of stay and decreased postoperative costs compared with the control subjects receiving unfractionated heparin.
Am J Cardiol. 2004 Jan 15;93(2):247-50.
The American journal of cardiology
Fanikos J, Tsilimingras K, Kucher N, Rosen AB, Hieblinger MD, Goldhaber SZ. (2004). Comparison of efficacy, safety, and cost of low-molecular-weight heparin with continuous-infusion unfractionated heparin for initiation of anticoagulation after mechanical prosthetic valve implantation. Population and Quantitative Health Sciences Publications. Retrieved from https://escholarship.umassmed.edu/qhs_pp/889