Randomized trial to improve fracture prevention in nursing home residents

UMMS Affiliation

Department of Quantitative Health Sciences

Publication Date


Document Type



Aged; Aged, 80 and over; Arizona; Female; Fractures, Bone; Fractures, Spontaneous; *Homes for the Aged; Humans; Male; Middle Aged; Multivariate Analysis; North Carolina; *Nursing Homes; Odds Ratio; Osteoporosis; Outcome and Process Assessment (Health Care); Quality Assurance, Health Care; Single-Blind Method


Bioinformatics | Biostatistics | Epidemiology | Health Services Research


BACKGROUND: Interventions to improve the fracture prevention in nursing homes are needed.

METHODS: Cluster-randomized, single-blind, controlled trial of a multi-modal quality improvement intervention. Nursing homes (n=67) with > or =10 residents with a diagnosis of osteoporosis or recent hip fracture (n=606) were randomized to receive an early or delayed intervention consisting of audit and feedback, educational modules, teleconferences, and academic detailing. Medical record abstraction and the Minimum Data Set were used to measure the prescription of osteoporosis therapies before and after the intervention period. Analysis was at the facility-level and Generalized Estimating Equation modeling was used to account for clustering.

RESULTS: No significant improvements were observed in any of the quality indicators. The use of osteoporosis pharmacotherapy or hip protectors improved by 8.0% in the intervention group and 0.6% in the control group, but the difference was not statistically significant (P=.72). Participation in the intervention activities was low, but completion of the educational module (odds ratio [OR] 4.8, 95% confidence interval [CI], 1.9-12.0) and direct physician contact by an academic detailer (OR 4.5, 95% CI, 1.1-18.2) were significantly associated with prescription of osteoporosis pharmacotherapy or hip protectors in multivariable models.

CONCLUSIONS: Audit-feedback and education interventions were ineffective in improving fracture prevention in the nursing home setting, although results may have been tempered by low participation in the intervention activities.

DOI of Published Version



Am J Med. 2007 Oct;120(10):886-92. Link to article on publisher's site

Journal/Book/Conference Title

The American journal of medicine

PubMed ID


Related Resources

Link to Article in PubMed