Department of Quantitative Health Sciences
Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Male; Middle Aged; Neoplasms; Risk Factors
Bioinformatics | Biostatistics | Epidemiology | Health Services Research
In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P<.0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P<.0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.
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© 2004 by the Infectious Diseases Society of America.
DOI of Published Version
Clin Infect Dis. 2004 Nov 1;39(9):1380-4. Epub 2004 Oct 11. Link to article on publisher's site
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 15937776
Bedimo R, Chen RY, Accortt NA, Raper JL, Linn C, Allison JJ, Dubay J, Saag MS, Hoesley CJ. (2004). Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002. Population and Quantitative Health Sciences Publications. https://doi.org/10.1086/424883. Retrieved from https://escholarship.umassmed.edu/qhs_pp/792