Endemic Burkitt's lymphoma: a polymicrobial disease
Department of Quantitative Health Sciences; Department of Pediatrics
Animals; B-Lymphocytes; Burkitt Lymphoma; Dendritic Cells; *Endemic Diseases; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Malaria, Falciparum; Plasmodium falciparum
Biostatistics | Epidemiology | Health Services Research | Immunology and Infectious Disease | Pediatrics
Endemic Burkitt's lymphoma is the most common childhood cancer in equatorial Africa. Two ubiquitous human pathogens are thought to be responsible for the aetiology of this disease: Epstein-Barr virus and Plasmodium falciparum malaria. New data suggest how these two pathogens might interact to result in disease and provide insights into the emerging concepts of polymicrobial disease pathogenesis.
DOI of Published Version
Nat Rev Microbiol. 2005 Feb;3(2):182-7. Link to article on publisher's site
Nature reviews. Microbiology
Rochford, Rosemary A.; Cannon, Martin J.; and Moormann, Ann M., "Endemic Burkitt's lymphoma: a polymicrobial disease" (2005). Quantitative Health Sciences Publications and Presentations. 412.