Exposure to anesthetic gases and reproductive outcome. A review of the epidemiologic literature
Department of Medicine, Division of Cardiovascular Medicine
Abnormalities, Drug-Induced; Abortion, Spontaneous; *Anesthesiology; Anesthetics; Data Collection; Epidemiologic Methods; Female; Great Britain; Humans; Male; Occupational Diseases; Pregnancy; Reproduction; Risk; United States
Biostatistics | Epidemiology | Health Services Research
A variety of evidence suggests that chronic exposure to low doses of anesthetic gases, as occurs in the occupational setting, is a risk factor for spontaneous abortion and congenital defects. The major epidemiologic studies are reviewed, and it is suggested that, due to significant flaws in the design and conduct of these observational studies, there is inadequate evidence to conclude that occupational exposure to anesthetic agents causes increased rates of spontaneous abortion or congenital anomalies.
J Occup Med. 1985 Sep;27(9):659-68.
Journal of occupational medicine. : official publication of the Industrial Medical Association
Tannenbaum, T. N. and Goldberg, Robert J., "Exposure to anesthetic gases and reproductive outcome. A review of the epidemiologic literature" (1985). Quantitative Health Sciences Publications and Presentations. 200.