Title

Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample

UMMS Affiliation

Division of Epidemiology, Department of Population and Quantitative Health Sciences; Clinical and Population Health Research Program, Graduate School of Biomedical Sciences; Division of Biostatistics and Health Services Research, Department of Population and Quantitative Health Sciences; Division of Rheumatology, Department of Medicine

Publication Date

2021-01-15

Document Type

Article

Disciplines

Epidemiology | Gender and Sexuality | Health Services Research | Mental and Social Health | Musculoskeletal Diseases | Rheumatology

Abstract

Objectives: We described the burden of illness and health-related quality of life (HRQoL) in adults with spondyloarthritis (SpA) using a nationally representative sample.

Materials and Methods: We identified participants with SpA using the Amor classification criteria (probable: score 5 or definite: > /=6) and complete data on HRQoL from the 2009 to 2010 National Health and Nutrition Examination Survey (n = 231). HRQoL was measured using the Healthy Days Measures including self-rated health status (excellent/very good, good, fair/poor), number of activity-restricted days, and number of unhealthy mental and physical health days in the past month (range: 0-30). Other domains including clinical assessments, comorbidities, physical functioning, and medication use were also explored.

Results: Only 39% of the sample met the Amor criteria for definite SpA. Although 58% of those with definite SpA had seen a doctor > 3 times in the past year, 2.5% women and 4.1% men had ever been told by a physician that they have ankylosing spondylitis. Among those with definite SpA, racial/ethnic diversity was observed in women (13.6% non-Hispanic Black, 23.2% Hispanic) and men (11.6% non-Hispanic Black, 11.2% Hispanic). Overall, 41.6% women and 49.7% men rated their health as fair/poor. For other HRQoL measures, 25.4% women and 20.4% men reported > /=15 activity-restricted days and 39.7% women and 41.4% men reported > /=15 physically unhealthy days.

Conclusion: Both men and women rank health as poor with indications that it affects QoL. Although our small sample size limits definitive statements, we observed trends that warrant further confirmation in larger population-based samples.

Keywords

health-related quality of life, population-based study, sex, spondyloarthritis

DOI of Published Version

10.1089/jwh.2020.8763

Source

Shridharmurthy D, Zhao D, Lapane KL, Baek J, Kay J, Liu SH. Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample. J Womens Health (Larchmt). 2021 Jan 15. doi: 10.1089/jwh.2020.8763. Epub ahead of print. PMID: 33450162. Link to article on publisher's site

Journal/Book/Conference Title

Journal of women's health (2002)

PubMed ID

33450162

Related Resources

Link to Article in PubMed

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