Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample
Division of Epidemiology, Department of Population and Quantitative Health Sciences; Clinical and Population Health Research Program, Graduate School of Biomedical Sciences; Division of Biostatistics and Health Services Research, Department of Population and Quantitative Health Sciences; Division of Rheumatology, Department of Medicine
Epidemiology | Gender and Sexuality | Health Services Research | Mental and Social Health | Musculoskeletal Diseases | Rheumatology
Objectives: We described the burden of illness and health-related quality of life (HRQoL) in adults with spondyloarthritis (SpA) using a nationally representative sample.
Materials and Methods: We identified participants with SpA using the Amor classification criteria (probable: score 5 or definite: > /=6) and complete data on HRQoL from the 2009 to 2010 National Health and Nutrition Examination Survey (n = 231). HRQoL was measured using the Healthy Days Measures including self-rated health status (excellent/very good, good, fair/poor), number of activity-restricted days, and number of unhealthy mental and physical health days in the past month (range: 0-30). Other domains including clinical assessments, comorbidities, physical functioning, and medication use were also explored.
Results: Only 39% of the sample met the Amor criteria for definite SpA. Although 58% of those with definite SpA had seen a doctor > 3 times in the past year, 2.5% women and 4.1% men had ever been told by a physician that they have ankylosing spondylitis. Among those with definite SpA, racial/ethnic diversity was observed in women (13.6% non-Hispanic Black, 23.2% Hispanic) and men (11.6% non-Hispanic Black, 11.2% Hispanic). Overall, 41.6% women and 49.7% men rated their health as fair/poor. For other HRQoL measures, 25.4% women and 20.4% men reported > /=15 activity-restricted days and 39.7% women and 41.4% men reported > /=15 physically unhealthy days.
Conclusion: Both men and women rank health as poor with indications that it affects QoL. Although our small sample size limits definitive statements, we observed trends that warrant further confirmation in larger population-based samples.
health-related quality of life, population-based study, sex, spondyloarthritis
DOI of Published Version
Shridharmurthy D, Zhao D, Lapane KL, Baek J, Kay J, Liu SH. Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample. J Womens Health (Larchmt). 2021 Jan 15. doi: 10.1089/jwh.2020.8763. Epub ahead of print. PMID: 33450162. Link to article on publisher's site
Journal of women's health (2002)
Shridharmurthy D, Zhao D, Lapane KL, Baek J, Kay J, Liu S. (2021). Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample. Population and Quantitative Health Sciences Publications. https://doi.org/10.1089/jwh.2020.8763. Retrieved from https://escholarship.umassmed.edu/qhs_pp/1399