UMMS Affiliation

Department of Quantitative Health Sciences

Publication Date


Document Type



Health Psychology | Health Services Research | Mental and Social Health | Psychiatry and Psychology | Psychological Phenomena and Processes | Race and Ethnicity


Biological age (BA) is a construct that captures accelerated biological aging attributable to "wear and tear" from various exposures; we measured BA and weathering, defined as the difference between BA and chronological age, and their associations with race and psychosocial factors in a middle-aged bi-racial cohort. We used data from the Coronary Artery Risk in Young Adults study (CARDIA), conducted in 4 U.S. cities from 1985-2016 to examine weathering for adults aged 48-60 years. We estimated BA via the Klemera and Doubal method using selected biomarkers. We assessed overall and race-specific associations between weathering and psychosocial measures. For the 2694 participants included, Blacks had a BA (SD) that was 2.6 (11.8) years older than their chronological age while the average BA among Whites was 3.5 (10.0) years younger than their chronological age (Blacks weathered 6.1 years faster than Whites). Belonging to more social groups was associated with less weathering in Blacks but not Whites, and after multivariable adjustment, lower SES and more depressive symptoms were associated with more weathering among Blacks than among Whites. We confirmed racial differences in weathering, and newly documented that similar psychosocial factors may take a greater toll on the biological health of Blacks than Whites.


Biological age, Psychosocial factors, racial disparity, Weathering

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© 2018 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (

DOI of Published Version



SSM Popul Health. 2018 Nov 6;7:003-3. doi: 10.1016/j.ssmph.2018.11.003. eCollection 2019 Apr. Link to article on publisher's site

Journal/Book/Conference Title

SSM - population health

PubMed ID


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Link to Article in PubMed

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.