Title

Echocardiographic assessment of right ventricular systolic function in Boxers with arrhythmogenic right ventricular cardiomyopathy

UMMS Affiliation

Department of Quantitative Health Sciences

Publication Date

2018-10-01

Document Type

Article

Disciplines

Veterinary Medicine

Abstract

OBJECTIVES: To determine whether there are differences in measures of longitudinal right ventricular (RV) systolic function among Boxers with arrhythmogenic right ventricular cardiomyopathy (ARVC) compared with healthy control Boxer dogs. To explore relationships between markers of RV systolic function and age, body weight, gender, arrhythmia frequency, and markers of left ventricular (LV) systolic function in Boxer dogs.

ANIMALS: The study included 50 client-owned Boxer dogs.

METHODS: This is a retrospective echocardiographic study. Tricuspid annular plane systolic excursion (TAPSE) and pulsed wave tissue Doppler imaging-derived systolic myocardial velocity of the lateral tricuspid annulus (S') were measured in healthy control Boxers (n = 18), Boxers with ARVC and normal LV systolic function (n = 19), and Boxers with ARVC and reduced LV systolic function (n = 13).

RESULTS: Tricuspid annular plane systolic excursion (p=0.002) and S' (p=0.001) were significantly different between affected and control groups. Significant correlations were found between measures of left heart size and function and both TAPSE and S'. No correlations were found between RV function parameters and age, gender, or body weight in this fairly homogeneous, single-breed population. Receiver operating characteristic curve analysis revealed that both TAPSE and S' had an area under the curve of 0.77 in distinguishing healthy Boxers from those with ARVC.

CONCLUSIONS: Tricuspid annular plane systolic excursion and S' are reduced in Boxers with ARVC. In contrast to prior studies evaluating these parameters in dogs of different breeds and body types, no correlation was found between markers of RV function and body weight in this population of Boxer dogs.

Keywords

Arrhythmia, Canine, Cardiac, Right ventricle

DOI of Published Version

10.1016/j.jvc.2018.07.005

Source

J Vet Cardiol. 2018 Oct;20(5):343-353. doi: 10.1016/j.jvc.2018.07.005. Epub 2018 Aug 20. Link to article on publisher's site

Journal/Book/Conference Title

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology

PubMed ID

30139648

Related Resources

Link to Article in PubMed

Share

COinS