Timing of video capsule endoscopy relative to overt obscure GI bleeding: implications from a retrospective study

UMMS Affiliation

Department of Quantitative Health Sciences; Department of Medicine, Division of Gastroenterology; Graduate Medical Education

Publication Date


Document Type



Digestive System Diseases | Epidemiology | Gastroenterology | Health Services Research


BACKGROUND: Diagnostic yield of video capsule endoscopy (VCE) may be higher if it is performed closer to the time of overt obscure GI bleeding (OOGIB).

OBJECTIVE: To evaluate the diagnostic yield of VCE and rate of therapeutic intervention for OOGIB for inpatients and outpatients with respect to timing of the intervention.

DESIGN: Retrospective cohort study.

SETTING: Tertiary academic center.

PATIENTS: Patients who had VCE for OOGIB between August 2008 and August 2010.

INTERVENTIONS: VCE for inpatients versus outpatients.

MAIN OUTCOME MEASURES: Diagnostic yield and rate of therapeutic intervention for inpatients versus outpatients.

RESULTS: One hundred forty-four inpatients (65 women) and 116 outpatients (49 women) were included. Diagnostic yield was 65.9% for inpatients versus 53.4% for outpatients (P = .054). Inpatients were divided into those who had VCE within 3 days (days; n = 90) of admission versus after 3 days (>3 days; n = 54). Active bleeding and/or an angioectasia was found in 44.4% of the 3-day group (P = .046) versus 25.8% of the outpatients. Therapeutic intervention was performed in 18.9% of the 3-day group (P = .046) versus 10.3% of outpatients. Diagnostic yield and therapeutic intervention rate between the >3-day group and outpatients were not significantly different. Length of stay (days) was less in the 3-day cohort (P < .0001).

LIMITATIONS: Long-term outcomes were not studied. This was a retrospective study.

CONCLUSIONS: Early deployment of VCE within 3 days of admission results in a higher diagnostic yield and therapeutic intervention rate and an associated reduction of length of stay. Mosby, Inc. All rights reserved.


UMCCTS funding

DOI of Published Version



Gastrointest Endosc. 2013 May;77(5):761-6. doi: 10.1016/j.gie.2012.11.041. Epub 2013 Feb 1. Link to article on publisher's site

Journal/Book/Conference Title

Gastrointestinal endoscopy

PubMed ID


Related Resources

Link to Article in PubMed