Methodological Issues in Designing a Randomized Controlled Trial for Psychotic Depression: The STOP-PD Study
Department of Psychiatry
Depressive Disorder, Major; Affective Disorders, Psychotic
The safety and efficacy of electroconvulsive therapy (ECT) has been documented for more than half a century, including among patients with major depressive disorder with psychotic features (MD-Psy) who have failed intensive antidepressant treatment. More recent studies from academic centers that use contemporary ECT standards have demonstrated response and remission rates exceeding 90% among patients with MD-Psy.
Meyers BS, Peasley-Miklus C, Flint AJ, Mulsant BH, Rothschild AJ: Methodological Issues In Designing A Randomized Controlled Trial For Psychotic Depression: The STOP-PD Study. Psych Annals, 2006; 36:57-64.
Meyers, Barnett S.; Peasley-Miklus, Catherine; Flint, Alastair J.; Mulsant, Benoit H.; and Rothschild, Anthony J., "Methodological Issues in Designing a Randomized Controlled Trial for Psychotic Depression: The STOP-PD Study" (2006). Psychiatry Publications and Presentations. 97.