Title

Childhood Trauma and Psychosis: An Updated Review

UMMS Affiliation

Department of Psychiatry

Publication Date

2020-01-01

Document Type

Article

Disciplines

Mental and Social Health | Pediatrics | Psychiatry | Psychiatry and Psychology

Abstract

There is growing evidence to support the link between childhood trauma and psychosis. Childhood trauma increases the risk for psychosis and affects severity and type of psychotic symptoms, and frequency of comorbid conditions, including depression and substance use. Childhood trauma is linked to more severe functional impairment in individuals with psychosis. There is evidence to support gender differences in the influence of childhood trauma on the course of psychotic illnesses, appearing to be more profound in girls and women. Other biological markers that may explain the link between childhood trauma and psychosis include brain-derived neurotrophic factor and other inflammatory markers.

Keywords

Childhood abuse, Childhood adversity, Childhood trauma, Psychosis

DOI of Published Version

10.1016/j.chc.2019.08.004

Source

Child Adolesc Psychiatr Clin N Am. 2020 Jan;29(1):115-129. doi: 10.1016/j.chc.2019.08.004. Epub 2019 Sep 23. Link to article on publisher's site

Journal/Book/Conference Title

Child and adolescent psychiatric clinics of North America

Related Resources

Link to Article in PubMed

PubMed ID

31708041

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