Brain mechanisms of Change in Addictions Treatment: Models, Methods, and Emerging Findings
Department of Medicine; Department of Psychiatry
Behavior and Behavior Mechanisms | Cognitive Behavioral Therapy | Mental and Social Health | Mental Disorders | Neuroscience and Neurobiology | Psychiatry | Psychiatry and Psychology | Substance Abuse and Addiction
Increased understanding of "how" and "for whom" treatment works at the level of the brain has potential to transform addictions treatment through the development of innovative neuroscience-informed interventions. The 2015 Science of Change meeting bridged the fields of neuroscience and psychotherapy research to identify brain mechanisms of behavior change that are "common" across therapies, and "specific" to distinct behavioral interventions. Conceptual models of brain mechanisms underlying effects of Cognitive Behavioral Therapy, mindfulness interventions, and Motivational Interviewing were discussed. Presentations covered methods for integrating neuroimaging into psychotherapy research, and novel analytic approaches. Effects of heavy substance use on the brain, and recovery of brain functioning with sustained abstinence, which may be facilitated by cognitive training, were reviewed. Neuroimaging provides powerful tools for determining brain mechanisms underlying psychotherapy and medication effects, predicting and monitoring outcomes, developing novel interventions that target specific brain circuits, and identifying for whom an intervention will be effective.
addictive behaviors, alcohol, neuroimaging psychotherapy, substance use disorder, translational
DOI of Published Version
Curr Addict Rep. 2016 Sep;3(3):332-342. Epub 2016 Jul 9. Link to article on publisher's site
Current addiction reports
Chung, Tammy; Brewer, Judson A.; and Feldstein Ewing, Sarah W., "Brain mechanisms of Change in Addictions Treatment: Models, Methods, and Emerging Findings" (2016). Psychiatry Publications and Presentations. 821.