Empirical evidence for psychopharmacologic treatment in early-onset psychosis and schizophrenia

UMMS Affiliation

Department of Psychiatry



Document Type


Medical Subject Headings

Antipsychotic Agents; Psychotic Disorders; Schizophrenia


Medical Pharmacology | Mental and Social Health | Psychiatry | Psychiatry and Psychology


Psychotic symptoms presenting in youth can be clinically complex and require that a child and adolescent psychiatrist use significant skill in making a diagnosis and initiating treatment. There are a number of illnesses to rule out before making a diagnosis of early-onset schizophrenia in particular. Psychosis in youth has significant associated morbidity and places high demands not only on families but also on the medical and educational systems. More effective pharmacologic and nonpharmacologic treatments for psychosis are needed. Nonpharmacologic therapies targeting relatively treatment-resistant domains of dysfunction such as neurocognition are also necessary as adjunctive treatments to our extant pharmacologic agents.


Citation: Child Adolesc Psychiatr Clin N Am. 2012 Oct;21(4):885-909. doi: 10.1016/j.chc.2012.07.011. Link to article on publisher's site

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