Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series
Authors
Doyle, Robert L.Frazier, Jean A.
Spencer, Thomas J.
Geller, Daniel A.
Biederman, Joseph
Wilens, Timothy E.
UMass Chan Affiliations
Department of PsychiatryDocument Type
Journal ArticlePublication Date
2006-02-17Keywords
AdolescentAttention Deficit Disorder with Hyperactivity
Child
Child Development Disorders, Pervasive
Cholinesterase Inhibitors
Communication
Drug Administration Schedule
Female
Humans
Indans
Male
Piperidines
Social Behavior
Psychiatry
Metadata
Show full item recordAbstract
BACKGROUND: Recent studies reported ADHD-like symptoms and cognitive deficits in pervasive developmental disorder (PDD). Because work in dementia documents improvement in executive function deficits with the acetylcholinesterase inhibitor donepezil, the authors reason that similar benefits could be obtained in PDD. METHOD: The authors describe eight cases of PDD youth ages 10 to 17 treated with donepezil targeting ADHD-like symptoms associated with PDD. RESULTS: Most participants improve ADHD-like symptomatology. In addition, improvement in communication and socialization is noted. CONCLUSION: Donepezil may have a role in treating ADHD-like symptoms in children with PDD.Source
J Atten Disord. 2006 Feb;9(3):543-9. Link to article on publisher's siteDOI
10.1177/1087054705284091Permanent Link to this Item
http://hdl.handle.net/20.500.14038/45874PubMed ID
16481671Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1177/1087054705284091