Title
Smooth pursuit eye movements in childhood-onset schizophrenia: comparison with attention-deficit hyperactivity disorder and normal controls
UMMS Affiliation
Department of Psychiatry
Publication Date
1996-12-01
Document Type
Article
Subjects
Adolescent; Attention Deficit Disorder with Hyperactivity; Brain; Cerebral Ventricles; Child; Cognition; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Psychiatric Status Rating Scales; Psychomotor Performance; Pursuit, Smooth; Schizophrenia, Childhood; Schizophrenic Psychology
Disciplines
Psychiatry
Abstract
Abnormalities of the smooth pursuit eye movements of adults with schizophrenia have been well described. We examined smooth pursuit eye movements in schizophrenic children, contrasting them with normal and attention-deficit hyperactivity disorder (ADHD) subjects, to determine whether there is continuity of eye movement dysfunction between childhood- and adult-onset forms of schizophrenia. Seventeen schizophrenic children with onset of illness by age 12, 18 ADHD children, and 22 normal children were studied while engaged in a smooth pursuit eye tracking task. Eye tracking variables were compared across the three groups. Schizophrenic children exhibited significantly greater smooth pursuit impairments than either normal or ADHD subjects. Within the schizophrenic group, there were no significant relationships between eye tracking variables and clinical variables, or ventricular/brain ratio. Childhood-onset schizophrenia is associated with a similar pattern of smooth pursuit abnormalities to that seen in later-onset schizophrenia.
DOI of Published Version
10.1016/S0006-3223(95)00630-3
Source
Biol Psychiatry. 1996 Dec 1;40(11):1144-54. Link to article on publisher's site
Journal/Book/Conference Title
Biological psychiatry
Related Resources
PubMed ID
8931918
Repository Citation
Jacobsen LK, Hong WL, Hommer DW, Hamburger SD, Castellanos F, Frazier JA, Giedd JN, Gordon CT, Karp BI, McKenna K, Rapoport JL. (1996). Smooth pursuit eye movements in childhood-onset schizophrenia: comparison with attention-deficit hyperactivity disorder and normal controls. Psychiatry Publications. https://doi.org/10.1016/S0006-3223(95)00630-3. Retrieved from https://escholarship.umassmed.edu/psych_pp/370