Title

The dexamethasone suppression test: identification of subtypes of depression

UMMS Affiliation

Department of Psychiatry

Publication Date

1983-01-01

Document Type

Article

Subjects

Adolescent; Adult; Aged; Bipolar Disorder; Depressive Disorder; Dexamethasone; Diagnosis, Differential; Female; Humans; Hydrocortisone; Male; Middle Aged

Disciplines

Psychiatry

Abstract

In this study mean 4 p.m. cortisol levels were significantly higher in patients with major depression than in control subjects or in patients with bipolar depression or dysthymic-related disorders. Moreover, the distribution of values differed significantly among groups. Eighteen of 45 patients with major depression had cortisol levels of 10 micrograms/dl or more, compared with 2 of 20 bipolar depressed patients and 0 of 31 controls. Patients with very high cortisol levels (15 micrograms/dl or more) tended to fulfill criteria for major depression with mood-congruent psychosis. The distribution of values in the major depression group also suggested the existence of three major subgroups. The authors discuss the implications of these data.

Source

Am J Psychiatry. 1983 Jan;140(1):88-91.

Journal/Book/Conference Title

The American journal of psychiatry

Related Resources

Link to Article in PubMed

PubMed ID

6847992

Share

COinS