Comorbid Pain and Opioid Addiction: Psychosocial and Pharmacological Treatments

UMMS Affiliation

Department of Psychiatry

Publication Date


Document Type



Chronic Disease; Complementary Therapies; Demography; Humans; Narcotic Antagonists; Opioid-Related Disorders; Pain; Psychotherapy; Validation Studies as Topic


Health Services Research | Mental and Social Health | Psychiatric and Mental Health | Psychiatry | Psychiatry and Psychology


Treating comorbid pain (nonmalignant) and opioid addiction is a complex endeavor that requires cooperation of multi-modal treatment teams incorporating pharmacological, psychological, and social components. There are multiple barriers for patients, mental health practitioners, and physical health practitioners to provide complete treatment for this difficult treatment population. In this article, we will review which treatments have been empirically validated in this treatment population, where further research is required, and considerations for potential "best approaches" to use for patient treatment while waiting for empirically validated treatment data. We will also discuss some complementary and alternative medicine approaches that have empirical validity in treating either pain or addiction individually, though empirical validity for the treatment of comorbid pain and addiction has not been established.

DOI of Published Version



Subst Use Misuse. 2011;46(12):1536-52. Epub 2011 Jul 14. Link to article on publisher's site

Journal/Book/Conference Title

Substance use and misuse

Related Resources

Link to Article in PubMed