Hypothalamic lesions and intermittent explosive disorder
Department of Psychiatry
Adult; Aggression; Craniopharyngioma; Delirium, Dementia, Amnestic, Cognitive; Disorders; Female; Follow-Up Studies; Humans; Hypothalamo-Hypophyseal System; Magnetic Resonance Imaging; Male; Neurologic Examination; Neuropsychological Tests; Pituitary Neoplasms; *Violence
Health Services Research | Mental and Social Health | Psychiatric and Mental Health | Psychiatry | Psychiatry and Psychology
The authors present two cases of patients with craniopharyngiomas who meet the DSM-III-R criteria for intermittent explosive disorder. Episodes of rage developed before and/or after surgery for removal of the craniopharyngioma. Magnetic resonance imaging revealed hypothalamic-hypophyseal involvement. It is suggested that hypothalamic lesions played a major role in the development of aggressive behavior in both cases.
J Neuropsychiatry Clin Neurosci. 1992 Winter;4(1):45-50.
The Journal of neuropsychiatry and clinical neurosciences
Tonkonogy, Joseph M. and Geller, Jeffrey L., "Hypothalamic lesions and intermittent explosive disorder" (1992). Systems and Psychosocial Advances Research Center Publications and Presentations. 164.