Title
Development of an updated phytoestrogen database for use with the SWAN food frequency questionnaire: intakes and food sources in a community-based, multiethnic cohort study
UMMS Affiliation
Department of Medicine, Division of Preventive and Behavioral Medicine
Publication Date
2012-01-02
Document Type
Article
Subjects
Adult; Cohort Studies; Coumestrol; *Databases, Factual; Diet; Female; *Food; Food Analysis; Humans; Isoflavones; Lignans; Longitudinal Studies; MEDLINE; Middle Aged; Phytoestrogens; *Questionnaires; Residence Characteristics; United States; Women's Health
Disciplines
Community Health and Preventive Medicine | Dietetics and Clinical Nutrition | Epidemiology | Preventive Medicine
Abstract
Phytoestrogens, heterocyclic phenols found in plants, may benefit several health outcomes. However, epidemiologic studies of the health effects of dietary phytoestrogens have yielded mixed results, in part due to challenges inherent in estimating dietary intakes. The goal of this study was to improve the estimates of dietary phytoestrogen consumption using a modified Block Food Frequency Questionnaire (FFQ), a 137-item FFQ created for the Study of Women's Health Across the Nation (SWAN) in 1994. To expand the database of sources from which phytonutrient intakes were computed, we conducted a comprehensive PubMed/Medline search covering January 1994 through September 2008. The expanded database included 4 isoflavones, coumestrol, and 4 lignans. The new database estimated isoflavone content of 105 food items (76.6%) vs. 14 (10.2%) in the 1994 version and computed coumestrol content of 52 food items (38.0%), compared to 1 (0.7%) in the original version. Newly added were lignans; values for 104 FFQ food items (75.9%) were calculated. In addition, we report here the phytonutrient intakes for each racial and language group in the SWAN sample and present major food sources from which the phytonutrients came. This enhanced ascertainment of phytoestrogens will permit improved studies of their health effects.
DOI of Published Version
10.1080/01635581.2012.638434
Source
Nutr Cancer. 2012;64(2):228-44. Epub 2012 Jan 2. Link to article on publisher's site
Journal/Book/Conference Title
Nutrition and cancer
Related Resources
PubMed ID
22211850
Repository Citation
Huang, Mei-Hua; Norris, Jean; han, Weijun; Block, Torin; Gold, Ellen B.; Crawford, Sybil L.; and Greendale, Gail A., "Development of an updated phytoestrogen database for use with the SWAN food frequency questionnaire: intakes and food sources in a community-based, multiethnic cohort study" (2012). Preventive and Behavioral Medicine Publications. 242.
https://escholarship.umassmed.edu/prevbeh_pp/242
