The Program in Molecular Medicine at the University of Massachusetts Medical School was established in a new research building in 1989. Faculty include both clinical investigators and basic scientists, many of whom focus their research on human disease processes. The laboratory groups and core facilities that compose Molecular Medicine represent many disciplines in the bio-medical sciences: biochemistry and molecular biology, cell biology, medicine, immunology, molecular genetics and microbiology, pediatrics, pharmacology, physiology, genomics, bioinformatics and proteomics. This diverse scientific environment makes the Program an exceptional training ground for graduate students and postdoctoral fellows, who in turn contribute much to its vitality and excitement. This collection showcases publications and presentations written by faculty and researchers of the Program in Molecular Medicine.

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Publications from 2016

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A Role for the Lipid Droplet Protein HIG2 in Promoting Lipid Deposition in Liver and Adipose Tissue: A Dissertation, Marina T. DiStefano

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Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations, Maria J. Duenas-Decamp, Li Jiang, Daniel N. Bolon, and Paul R. Clapham

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Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice, Asma Ejaz, Jason K. Kim, Mary-Elizabeth Patti, and Carles Lerin

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Emerging evidence for beneficial macrophage functions in atherosclerosis and obesity-induced insulin resistance, Timothy P. Fitzgibbons and Michael P. Czech

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Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance, Randall H. Friedline, Hwi Jin Ko, Dae Young Jung, Yongjin Lee, Rita Bortell, Sezin Dagdeviren, Payal R. Patel, Xiaodi Hu, Kunikazu Inashima, Caitlyn C. Kearns, Nicholas Tsitsilianos, Umber Shafiq, Dale L. Greiner, and Jason K. Kim

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A gene-centered C. elegans protein-DNA interaction network provides a framework for functional predictions, Juan Fuxman Bass, Carles Pons, Lucie Kozlowski, John S. Reece-Hoyes, Shaleen Shrestha, Amy D. Holdorf, Akihiro Mori, Chad L. Myers, and Albertha J. M. Walhout

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Colony Lift Colorimetric Assay for beta-Galactosidase Activity, Juan Fuxman Bass, John S. Reece-Hoyes, and Albertha J. M. Walhout (Cold Spring Harbor protocols, 12-1-2016)

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Gene-Centered Yeast One-Hybrid Assays, Juan Fuxman Bass, John S. Reece-Hoyes, and Albertha J. M. Walhout (Cold Spring Harbor protocols, 12-1-2016)

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Generating Bait Strains for Yeast One-Hybrid Assays, Juan Fuxman Bass, John S. Reece-Hoyes, and Albertha J. M. Walhout (Cold Spring Harbor protocols, 12-1-2016)

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Performing Yeast One-Hybrid Library Screens, Juan Fuxman Bass, John S. Reece-Hoyes, and Albertha J. M. Walhout (Cold Spring Harbor protocols, 12-1-2016)

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Zymolyase-Treatment and Polymerase Chain Reaction Amplification from Genomic and Plasmid Templates from Yeast, Juan Fuxman Bass, John S. Reece-Hoyes, and Albertha J. M. Walhout (Cold Spring Harbor protocols, 12-1-2016)

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Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2), Simona S. Ghanem, Dae Young Jung, Yongjin Lee, Jason K. Kim, and Sonia M. Najjar

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TNFalpha-Mediated Cytotoxic Responses to IAP Inhibition Are Limited by the p38alpha MAPK Pathway, Nomeda Girnius and Roger J. Davis

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The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4, Megan M. Gnazzo, Eva-Maria E. Uhlemann, Alex R. Villarreal, Masaki Shirayama, Eddie G. Dominguez, and Ahna R. Skop

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P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer, Hira Lal Goel, Bryan M. Pursell, Leonard D. Shultz, Dale L. Greiner, Rolf A. Brekken, Craig W. Vander Kooi, and Arthur M. Mercurio

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Inflammation Mediated by JNK in Myeloid Cells Promotes the Development of Hepatitis and Hepatocellular Carcinoma, Myoung Souk Han, Tamera Barrett, Michael A. Brehm, and Roger J. Davis

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High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources, Reka A. Haraszti, Marie-Cecile Didiot, Ellen Sapp, John D. Leszyk, Scott A. Shaffer, Hannah E. Rockwell, Fei Gao, Niven R. Narain, Marian DiFiglia, Michael A. Kiebish, Neil Aronin, and Anastasia Khvorova

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Cell Signaling and Stress Responses, Gokhan S. Hotamisligil and Roger J. Davis

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mTORC2 Promotes Lipid Storage and Suppresses Thermogenesis in Brown Adipose Tissue in Part Through AKT-Independent Regulation of FoxO1: A Dissertation, Chien-Min Hung

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Roles of the Mother Centriole Appendage Protein Cenexin in Microtubule Organization during Cell Migration and Cell Division: A Dissertation, Hui-Fang Hung

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The Mother Centriole Appendage Protein Cenexin Modulates Lumen Formation through Spindle Orientation, Hui-Fan Hung, Heidi Hehnly, and Stephen J. Doxsey

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Improved B cell development in humanized NOD-scid IL2Rgammanull mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3, Sonal Jangalwe, Leonard D. Shultz, Anuja Mathew, and Michael A. Brehm

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GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis, Guillaume Jannot, Pascale Michaud, Miguel Quevillon Huberdeau, Louis Morel-Berryman, James A. Brackbill, Sandra Piquet, Katherine McJunkin, Kotaro Nakanishi, and Martin J. Simard

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Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice, Adam Jara, Xingbo Liu, Don Sim, Chance M. Benner, Silvana Duran-Ortiz, Yanrong Qian, Edward O. List, Darlene E. Berryman, Jason K. Kim, and John J. Kopchick

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Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo, Hyein Jeon, Jae Hwan Kim, Eunjung Lee, Young Jin Jang, Joe Eun Son, Jung Yeon Kwon, Tae-Gyu Lim, Sunghoon Kim, Jung Han Yoon Park, Jong-Eun Kim, and Ki Won Lee

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Frontline Science: Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation, Siddharth Jhunjhunwala, David Alvarez, Stephanie Aresta-DaSilva, Katherine Tang, Benjamin C. Tang, Dale Greiner, Peter E. Newburger, Ulrich H. von Andrian, Robert Langer, and Daniel G. Anderson

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ChREBP Regulates Fructose-induced Glucose Production Independently of Insulin Signaling, Mi-Sung Kim, Sarah A. Krawczyk, Ludivine Doridot, Alan J. Fowler, Jennifer X. Wang, Sunia A. Trauger, Hye Lim Noh, Hee Joon Kang, John K. Meissen, Matthew Blatnik, Jason K. Kim, Michelle Lai, and Mark A. Herman

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition), Daniel J. Klionsky, Roger J. Davis, Fen-Biao Gao, and Panagiotis D. Velentzas

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Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease, Peter L. Lee, Yuefeng Tang, Huawei Li, and David A. Guertin

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Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress, Chen Lin, Xinyuan Zhao, Desen Sun, Lingda Zhang, Wenpan Fang, Tingjia Zhu, Qiang Wang, Botao Liu, Saisai Wei, Guangdi Chen, Zhengping Xu, and Xiangwei Gao

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Activation of mTORC1 is essential for beta-adrenergic stimulation of adipose browning, Dianxin Liu, Marica Bordicchia, Chaoying Zhang, Huafeng Fang, Wan Wei, Jian-Liang Li, Adilson L. Guilherme, Kalyani V. P. Guntur, Michael P. Czech, and Sheila Collins

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Tead and AP1 Coordinate Transcription and Motility, Xiangfan Liu, Huapeng Li, Mihir S. Rajurkar, Qi Li, Jennifer L. Cotton, Jianhong Ou, Lihua J. Zhu, Hira L. Goel, Arthur M. Mercurio, Joo-Seop Park, Roger J. Davis, and Junhao Mao

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DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia, You Li, Hisato Yagi, Gregory M. Hendricks, Gregory J. Pazour, and Cecilia W. Lo

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Closing the net on retroviruses, Jeremy Luban

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alphavbeta6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor, Huimin Lu, Tao Wang, Zhong Jiang, Roger J. Davis, Thomas J. Fitzgerald, and Lucia R. Languino

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Early Combination Antiretroviral Therapy Limits Exposure to HIV-1 Replication and Cell-Associated HIV-1 DNA Levels in Infants, Margaret M. McManus, Eric O. Mick, Richard W. Hudson Jr., Lynne M. Mofenson, John L. Sullivan, Mohan Somasundaran, Katherine Luzuriaga, and PACTG 356 Investigators

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The Origin of Human White, Brown, and Brite/Beige Adipocytes, So Yun Min

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Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice, So Yun Min, Jamie Kady, Minwoo Nam, Raziel Rojas-Rodriguez, Aaron Berkenwald, Jong Hun Kim, Hye Lim Noh, Jason K. Kim, Marcus P. Cooper, Timothy P. Fitzgibbons, Michael A. Brehm, and Silvia Corvera

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Cellular perception and misperception: Internal models for decision-making shaped by evolutionary experience, Amir Mitchell and Wendell Lim (BioEssays : news and reviews in molecular, cellular and developmental biology, 9-1-2016)

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Malaria - how this parasitic infection aids and abets EBV-associated Burkitt lymphomagenesis, Ann M. Moormann and Jeffrey A. Bailey

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Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury, Jill Moser, Joris van Ark, Marcory C. van Dijk, Dale L. Greiner, Leonard D. Shultz, Harry van Goor, and Jan-Luuk Hillebrands

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CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis, Kentaro Nagaoka, K. Fujii, H. Zhang, K. Usuda, G. Watanabe, Maria Ivshina, and Joel D. Richter

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A novel ICK mutation causes ciliary disruption and lethal endocrine-cerebro-osteodysplasia syndrome, Machteld M. Oud, Gregory J. Pazour, Bruno Reversade, and Heleen H. Arts

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Regulatory T Cells in Endemic Burkitt Lymphoma Patients Are Associated with Poor Outcomes: A Prospective, Longitudinal Study, Emily Parsons, Juliana A. Otieno, John Michael Ong'echa, Christina E. Nixon, John Vulule, Christian Munz, V. Ann Stewart, and Ann M. Moormann

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Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development, Kasmir Ramo, Koichi Sugamura, Siobhan M. Craige, John F. Keaney Jr., and Roger J. Davis

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Identification and Characterization of MicroRNA Modulators in Caenorhabditis Elegans: A Dissertation, Zhiji Ren

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Staufen Negatively Modulates microRNA Activity in Caenorhabditis elegans, Zhiji Ren, Isana Veksler-Lublinsky, David Morrissey, and Victor R. Ambros

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Impact of Plasmodium falciparum Coinfection on Longitudinal Epstein-Barr Virus Kinetics in Kenyan Children, Arnold Reynaldi, Timothy E. Schlub, Kiprotich Chelimo, Peter Odada Sumba, Erwan Piriou, Sidney Ogolla, Ann M. Moormann, Rosemary A. Rochford, and Miles P. Davenport

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Modeling of EBV Infection and Antibody Responses in Kenyan Infants With Different Levels of Malaria Exposure Shows Maternal Antibody Decay is a Major Determinant of Early EBV Infection, Arnold Reynaldi, Timothy E. Schlub, Erwan Piriou, Sidney Ogolla, Odada P. Sumba, Ann M. Moormann, Rosemary Rochford, and Miles P. Davenport

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Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia, Rachel J. Roth Flach, Laura V. Danai, Marina DiStefano, Mark Kelly, Lorena Garcia Menendez, Agata Jurczyk, Rohit B. Sharma, Dae Young Jung, Jong Hun Kim, Jason K. Kim, Rita Bortell, Laura C. Alonso, and Michael P. Czech

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Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function, Rachel J. Roth Flach, Chang-An Guo, Laura V. Danai, Joseph C. Yawe, Sharvari Gujja, Yvonne J.K. Edwards, and Michael P. Czech

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Genetic link between renal birth defects and congenital heart disease, Jovenal T. San Agustin, Nikolai Klena, Kristi Granath, Ashok Panigrahy, Eileen Stewart, William Devine, Lara Strittmatter, Julie A. Jonassen, Xiaoqin Liu, Cecilia W. Lo, and Gregory J. Pazour

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Emerging Complexities in Adipocyte Origins and Identity, Joan Sanchez-Gurmaches, Chien-Min Hung, and David A. Guertin

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Activation of WNT/beta-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61, Makoto Sano, David R. Driscoll, Wilfredo E. De Jesus-Monge, Brian J. Quattrochi, Victoria A. Appleman, Jianhong Ou, Lihua (Julie) Zhu, and Brian C. Lewis

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beta1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation, Aejaz Sayeed, Huimin Lu, Qin Liu, David Deming Ii, Alexander Duffy, Peter McCue, Adam P. Dicker, Roger J. Davis, Dmitry Gabrilovich, Ulrich Rodeck, Dario C. Altieri, and Lucia R. Languino

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A Role for TNMD in Adipocyte Differentiation and Adipose Tissue Function: A Dissertation, Ozlem Senol-Cosar

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Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion, Ozlem Senol-Cosar, Rachel J. Roth Flach, Marina DiStefano, Anil K. Chawla, Sarah M. Nicoloro, Juerg R. Straubhaar, Olga T. Hardy, Hye Lim Noh, Jason K. Kim, Martin Wabitsch, Philipp E. Scherer, and Michael P. Czech

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Association between First Trimester Pregnancy Associated Plasma Protein–A (PAPP-A) and Gestational Diabetes Mellitus Development, Aylin Sert, Katherine Leung, Molly E. Waring, Raziel Rojas-Rodriguez, Silvia Corvera, and Tiffany A. Moore Simas

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Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals, Upasna Sharma, Colin C. Conine, Jeremy Shea, Ana Boskovic, Alan G. Derr, Xin Y. Bing, Clemence Belleannee, Alper Kucukural, Ryan W. Serra, Fengyun Sun, Lina Song, Benjamin R. Carone, Emiliano P. Ricci, Xin Z. Li, Lucas Fauquier, Melissa J. Moore, Robert Sullivan, Craig C. Mello, Manuel Garber, and Oliver J. Rando

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Impaired neurodevelopment by the low complexity domain of CPEB4 reveals a convergent pathway with neurodegeneration, Jihae Shin, Johnny S. Salameh, and Joel D. Richter

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Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation, Lorissa J. Smulan, Wei Ding, Elizaveta Freinkman, Sharvari Gujja, Yvonne J. Edwards K, and Amy K. Walker

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Mechanism of early dissemination and metastasis in Her2+ mammary cancer, , Maria Soledad Sosa, Nomeda Girnius, Roger J. Davis, and Julio A. Aguirre-Ghiso

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Targeted Delivery of Glucan Particle Encapsulated Gallium Nanoparticles Inhibits HIV Growth in Human Macrophages, Ernesto R. Soto, Olivia O'Connell, Fusun Dikengil, Paul J. Peters, Paul R. Clapham, and Gary R. Ostroff

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The RNase PARN-1 Trims piRNA 3' Ends to Promote Transcriptome Surveillance in C. elegans, Wen Tang, Shikui Tu, Heng-Chi Lee, Zhiping Weng, and Craig C. Mello

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Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism, Yuefeng Tang, Martina Wallace, Joan Sanchez-Gurmaches, Wen-Yu Hsiao, Huawei Li, Peter L. Lee, Santiago Vernia, Christian M. Metallo, and David A. Guertin

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Comparison of RNA isolation and associated methods for extracellular RNA detection by high-throughput quantitative polymerase chain reaction, Kahraman Tanriverdi, Alper Kucukural, Ekaterina Mikhalev, Selim E. Tanriverdi, Rosalind Lee, Victor R. Ambros, and Jane Freedman

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Inactivation of nuclear GSK3beta by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response, Tina M. Thornton, Pilar Delgado, Liang Chen, Beatriz Salas, Dimitry Krementsov, Miriam Fernandez, Santiago Vernia, Roger J. Davis, Ruth Heimann, Cory Teuscher, Michael S. Krangel, Almudena R. Ramiro, and Mercedes Rincon

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Fibroblast Growth Factor 21 Mediates Glycemic Regulation by Hepatic JNK, Santiago Vernia, Julie Cavanagh-Kyros, Tamera Barrett, Cathy Tournier, and Roger J. Davis

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An alternative splicing program promotes adipose tissue thermogenesis, Santiago Vernia, Yvonne J. K. Edwards, Myoung Souk Han, Julie Cavanagh-Kyros, Tamera Barrett, Jason K. Kim, and Roger J. Davis

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Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress, Santiago Vernia, Caroline Morel, Joseph C. Madara, Julie Cavanagh-Kyros, Tamera Barrett, Kathryn O. Chase, Norman J. Kennedy, Dae Young Jung, Jason K. Kim, Neil Aronin, Richard A. Flavell, Bradford B. Lowell, and Roger J. Davis

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Human basal body basics, Anastassiia Vertii, Hui-Fang Hung, Heidi Hehnly, and Stephen J. Doxsey

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Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases, Joseph V. Virbasius and Michael P. Czech

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Platelet functional and transcriptional changes induced by intralipid infusion, , Olga Vitseva, Kahraman Tanriverdi, Alper Kucukural, Eric O. Mick, Naomi Hamburg, Joseph Vita, and Jane E. Freedman

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Metagenomic Sequencing with Strain-Level Resolution Implicates Uropathogenic E. coli in Necrotizing Enterocolitis and Mortality in Preterm Infants, Doyle V. Ward, Matthias Scholz, Moreno Zolfo, Diana H. Taft, Kurt R. Schibler, Adrian Tett, Nicola Segata, and Ardythe L. Morrow

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Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans, Emma Watson, Viridiana Olin-Sandoval, Michael J. Hoy, Chi-Hua Li, Timo Louisse, Victoria Yao, Akihiro Mori, Amy D. Holdorf, Olga G. Troyanskaya, Markus Ralser, and Albertha J. M. Walhout

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Multisite phosphorylation by MAPK, Alan J. Whitmarsh and Roger J. Davis

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Macrophages Are Regulators of Whole Body Metabolism: A Dissertation, Joseph C. Yawe

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A Caenorhabditis elegans Genome-Scale Metabolic Network Model, L. Safak Yilmaz and Albertha J. M. Walhout (Cell systems, 5-25-2016)

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RNA polymerase II depletion promotes transcription of alternative mRNA species, Lijian Yu, Mayuri Rege, Craig L. Peterson, and Michael R. Volkert

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The molecular basis of the genesis of basal tone in internal anal sphincter, Cheng-Hai Zhang, Donghai Lui, Ping Lu, Kaizhi Zheng, Siobhan M. Craige, Lawrence Lifshitz, John F. Keaney Jr., Kevin E. Fogarty, Ronghua Zhuge, and Min-Sheng Zhu

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Intraflagellar transport protein IFT20 is essential for male fertility and spermiogenesis in mice, Zhengang Zhang, Wei Li, Yong Zhang, Ling Zhang, Maria E. Teves, Hong Liu, Jerome F. Strauss 3rd, Gregory J. Pazour, James A. Foster, Rex A. Hess, and Zhibing Zhang

Publications from 2015

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The p53R172H Mutant Does Not Enhance Hepatocellular Carcinoma Development and Progression, Leanne G. Ahronian, David R. Driscoll, David S. Klimstra, and Brian C. Lewis

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Biodistribution and function of extracellular miRNA-155 in mice, Shashi Bala, Timea Csak, Fatemeh Momen-Heravi, Dora Lippai, Karen Kodys, Donna Catalano, Abhishek Satishchandran, Victor R. Ambros, and Gyongyi Szabo

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Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants, Ankita Bansal, Lihua Julie Zhu, Kelvin Yen, and Heidi A. Tissenbaum

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SWI/SNF recruitment to a DNA double-strand break by the NuA4 and Gcn5 histone acetyltransferases, Gwendolyn M. Bennett and Craig L. Peterson

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Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets, David M. Blodgett, Anetta Nowosielska, Shaked Afik, Susanne Pechhold, Anthony J. Cura, Norman J. Kennedy, Soyoung Kim, Alper Kucukural, Roger J. Davis, Sally C. Kent, Dale L. Greiner, Manuel Garber, David M. Harlan, and Philip J. diLorio Jr.

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The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization, Markus-Frederik Bohn, Shivender Shandilya, Tania V. Silvas, Ellen A. Nalivaika, Takahide Kouno, Brian Kelch, Sean P. Ryder, Nese Kurt Yilmaz, Mohan Somasundaran, and Celia A. Schiffer

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DNA-binding-domain fusions enhance the targeting range and precision of Cas9, Mehmet Fatih Bolukbasi, Ankit Gupta, Sarah Oikemus, Alan G. Derr, Manuel Garber, Michael H. Brodsky, Lihua Julie Zhu, and Scot A. Wolfe

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MicroRNAs Protect the Robustness of Distal Tip Cell Migrations from Temperature Changes in Caenorhabditis elegans: A Dissertation, Samantha L. Burke

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Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans, Samantha L. Burke, Molly Hammell, and Victor R. Ambros

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A laminin 511 matrix is regulated by TAZ and functions as the ligand for the alpha6Bbeta1 integrin to sustain breast cancer stem cells, Cheng Chang, Hira Lal Goel, Huijie Gao, Bryan M. Pursell, Leonard D. Shultz, Dale L. Greiner, Sulev Ingerpuu, Manuel Patarroyo, Shiliang Cao, Elgene Lim, Junhao Mao, Karen Kulju. McKee, Peter D. Yurchenco, and Arthur M. Mercurio

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Alternatively Activated M2 Macrophages Improve Autologous Fat Graft Survival in a Mouse Model through Induction of Angiogenesis, Ava Chappell, Jorge Lujan-Hernandez, Dylan Perry, Silvia Corvera, and Janice F. Lalikos

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R loops regulate promoter-proximal chromatin architecture and cellular differentiation, Poshen B. Chen, Hsiuyi V. Chen, Diwash Acharya, Oliver J. Rando, and Thomas G. Fazzio

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RNA Interference in Caenorhabditis elegans, Darryl Conte Jr., Lesley T. MacNeil, Albertha J. M. Walhout, and Craig C. Mello (Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.], 1-5-2015)

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Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury, Francisco Javier Cubero, Gang Zhao, Yulia A. Nevzorova, Maximilian Hatting, Malika Al Masaoudi, Julien Verdier, Jin Peng, Frederik M. Schaefer, Nadine Hermanns, Mark V. Boekschoten, Christoph Grouls, Nikolaus Gassler, Fabian Kiessling, Michael Muller, Roger J. Davis, Christian Liedtke, and Christian Trautwein

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Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies, Rama Rao Damerla, Cheng Cui, George C. Gabriel, Xiaoqin Liu, Branch Craige, Brian C. Gibbs, Richard Francis, You Li, Bishwanath Chatterjee, Jovenal T. San Agustin, Thibaut Eguether, Ramiah Subramanian, George B. Witman, Jacques L. Michaud, Gregory J. Pazour, and Cecilia W. Lo (Human molecular genetics)

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Role of Protein Kinase Map4k4 in Energy Metabolism: A Dissertation, Laura V. Danai

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Inducible Deletion of Protein Kinase Map4k4 in Obese Mice Improves Insulin Sensitivity in Liver and Adipose Tissues, Laura V. Danai, Rachel J. Roth Flach, Joseph V Virbasius, Lorena Garcia Menendez, Dae Young Jung, Jong Hun Kim, Jason K. Kim, and Michael P. Czech

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Plasmodium falciparum Protein Microarray Antibody Profiles Correlate With Protection From Symptomatic Malaria in Kenya, Arlene E. Dent, Rie Nakajima, Li Liang, Elisabeth Baum, Ann M. Moormann, Peter Odada Sumba, John Vulule, Denise Babineau, Arlo Randall, D. Huw Davies, Philip L. Felgner, and James W. Kazura

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s-Adenosylmethionine Levels Govern Innate Immunity through Distinct Methylation-Dependent Pathways, Wei Ding, Lorissa J. Smulan, Nicole S. Hou, Stefan Taubert, Jennifer L. Watts, and Amy K. Walker